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The Potential Cardioprotective Mechanism of Sodium-Glucose Cotransporter 2 Inhibitors

Jeon JH

The potential mechanism by which sodium-glucose cotransporter 2 (SGLT2) inhibitors prevent cardiovascular disease (CVD) is being widely investigated. Improved insulin resistance, along with decreased body fat mass associated with SGLT2...
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Sleep Pattern and Factors Causing Sleep Disturbance in Adolescents with Cancer before and after Hospital Admission

Jung J, Lee EH, Yang YJ, Jang BY

PURPOSE: This is a descriptive study conducted in order to survey sleep patterns and factors responsible for sleep disturbance among adolescent cancer patients after hospital admission. METHODS: The study group included...
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Edematous Hyponatremia Treated with Tolvaptan in a Patient with Amyotrophic Lateral Sclerosis

Kim GH

Amyotrophic lateral sclerosis (ALS) patients rarely present with either syndrome of inappropriate antidiuretic hormone secretion or generalized edema. Tolvaptan is a selective vasopressin V2 receptor antagonist that produces effective aquaresis,...
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Consumption of an Excessive Amount of Ionic Beverage Can Trigger Adrenal Adenoma - Induced Severe Hypokalemic Rhabdomyolysis

Han JH, Choi YH, Jeong H, Yoon IC, Choi HJ, Choi HM, Oh DJ

Rhabdomyolysis results from acute damage to skeletal muscles caused by various conditions, of which hypokalemia is a recognized but rare example. Although primary aldosteronism may cause severe hypokalemia leading to...
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A Case of Isolated Glycosuria Mediated by an SLC5A2 Gene Mutation and Characterized by Postprandial Heavy Glycosuria Without Salt Wasting

Kim KM, Kwon SK, Kim HY

Familial renal glycosuria (FRG) is an inherited disorder characterized by persistent glycosuria in the absence of hyperglycemia. It is caused by mutations in the sodium-glucose co-transporter, leading to increase in...
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The Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME) Trial and Its Clinical Impact on Patterns of Prescription for Anti-Diabetes Medication

Kwon HS

Since 2008, the Food and Drug Administration has required cardiovascular (CV) safety trials for all anti-diabetic medications available in the USA. Thus, new agents like dipeptidyl peptidase 4 inhibitors and...
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Screening of functional components derived from fresh water laver, Prasiola japonica, and its pharmacological properties

Seo DW, Kim HJ, Jang SK, Jun M, Joo SS

  • KMID: 1498926
  • J Biomed Res.
  • 2013 Jun;14(2):83-90.
The aim of the current study was to analyze the active ingredients and to screen the pharmacological properties of freshwater laver, Prasiola japonica, the only species grown in Korea. According...
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Sudden syncopal attack after postobstructed diuresis under combined spinal epidural anesthesia

So JH, Shin WJ, Byun JW, Yeom JH

No abstract available.
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Intraoperative Fluid Management in Combined Liver-Kidney Transplantation

Kim JH, Lim BR, Jung JY

A review of the literature regarding combined liver-kidney transplantation (CLKT) does not provide adequate central venous pressure (CVP) values that would allow for unimpaired hepatic venous outflow and early renal...
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Acute Kidney Injury and Postobstructive Diuresis Caused by a 4 mm Urinary Calculus

Jung ES, Yang EM, Kim CJ

  • KMID: 2098919
  • J Korean Soc Pediatr Nephrol.
  • 2013 Oct;17(2):117-121.
Urinary obstructions from ureteral calculi are one of the causes of postrenal acute kidney injury (AKI). Here we present a case of AKI caused by a 4 mm ureteral calculus...
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Effect of a Diet with Unrestricted Sodium on Ascites in Patients with Hepatic Cirrhosis

Gu XB, Yang XJ, Zhu HY, Xu BY

  • KMID: 2053499
  • Gut Liver.
  • 2012 Jul;6(3):355-361.
BACKGROUND/AIMS: There has been debate on whether a sodium-restricted diet (SRD) should be used in cirrhotic patients with ascites in China in recent years. The purpose of this study was...
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Circadian Rhythm of ADH, Hypercalciuria, and Solute Diuresis as Pathogenesis of Enuresis

Kang HG

  • KMID: 2144665
  • J Korean Soc Pediatr Nephrol.
  • 2012 Apr;16(1):1-8.
Nocturnal polyuria is one of the main pathogenic mechanisms of enuresis. Disturbance of circadian rhythm of antidiuretic hormone (ADH or AVP), hypercalciuria, and/or solute diuresis are considered to cause nocturnal...
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A Case of Posterior Reversible Encephalopathy Syndrome in a Girl with Nephrotic Syndrome

Kim MJ, Hwang H, Jung YJ, Lee JH, Park JS, Jeong KS

  • KMID: 1993596
  • Kosin Med J.
  • 2011 Dec;26(2):167-172.
A 12-year-old girl with nephrotic syndrome was admitted to Kosin University Gospel Hospital because of progressive generalized edema and weight gain for the last one month. From the eighth day...
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Effects of Liriopis Tuber Water Extract on RANKL-induced Osteoclast Differentiation

Park KI, Oh J

  • KMID: 1449618
  • Korean J Phys Anthropol.
  • 2011 Dec;24(4):237-244.
Increased formation and activation of osteoclast lead to unwanted bone resorption. Several natural products which have inhibitory effects on osteoclast differentiation and function are under investigation to prevent and treat...
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Rhabdomyolysis and Acute Renal Failure Following an Intentional Overdose of Stacker 3 (A Caffeine-Containing Weight-Reduction Supplement)

Lee MJ

  • KMID: 2204101
  • J Korean Soc Clin Toxicol.
  • 2010 Jun;8(1):46-49.
"Stacker 3" is one of the most popular caffeine-containing weight-reduction supplements and it has ephedra-free properties as "Stacker 2 Ephedra-Free" in many countries, including Korea. We describe here a 26-year-old...
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Importance of Residual Water Permeability on the Excretion of Water during Water Diuresis in Rats

Cheema-Dhadli S, Chong CK, Kim N, Kamel KS, Halperin M

When the concentration of sodium (Na+) in arterial plasma (P(Na)) declines sufficiently to inhibit the release of vasopressin, water will be excreted promptly when the vast majority of aquaporin 2...
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Renal Pelvic Hematoma Induced by Delayed Re-bleeding After Renal Biopsy

Jeon DH, Seo JW, Kang Y, Lee DW, Lee HJ, Kim HJ, Chang SH, Park DJ

  • KMID: 2080116
  • Korean J Nephrol.
  • 2010 Nov;29(6):768-771.
Renal biopsy is a useful method for the diagnosis of kidney disease. Complications may occur and are usually associated with bleeding. However, delayed recurrent bleeding is so rare. We report...
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Central Diabetes Insipidus Surmised as from Post-obstructive Diuresis after Decompression Treatment for Neurogenic Bladder

Lee KW, Yang CW, Lim DJ, Kwon HS, Kang MJ, Kim ES, Yoon KH, Son HY, Cha BY

Post-obstructive diuresis after treatment for neurogenic bladder-induced obstructive kidney disease is a common symptom. As polyuria may develop in many other conditions as well, the present case is about a...
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Resistant hypertension: Causes and management

Park CH

  • KMID: 2305818
  • Korean J Med.
  • 2009 Apr;76(4):398-401.
Resistant hypertension is defined as when the blood pressure cannot be reduced to below 140/90 mmHg in patients who are adhering to an adequate and appropriate triple drug regimen that...
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Pathophysiological Implications of Sodium Transporters and Water Channels in the Kidney

Kim SW, Ma SK, Bae EH, Park JW, Lee JU

  • KMID: 2253199
  • Korean J Nephrol.
  • 2009 Jan;28(1):1-9.
Renal sodium and water reabsorption occurs through epithelial sodium transporters and aquaporin (AQP) water channels in various segments of tubules. We have demonstrated altered regulation of these transporters and channels...
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