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C3H/He Mice as an Incompatible Cholangiocarcinoma Model by Clonorchis sinensis, Dicyclanil and N-Nitrosodimethylamine

Uddin MH, Li S, Jin Y, Choi MH, Jang JJ, Hong ST

Clonorchis sinensis is a Group-I bio-carcinogen, associated with cholangiocarcinoma (CCA). The hamster is the only experimental model of C. sinensis-mediated CCA, but we oblige another animal model. The present study...
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Evaluation of Liver Function Using 99mTc-Lactosylated Serum Albumin Liver Scintigraphy in Rat with Acute Hepatic Injury Induced by Dimethylnitrosamine

Jeong SY, Lee J, Seo M, Yoo JA, Bae JH, Ahn BC, Hwang JS, Jeong JM, Ha JH, Lee KB

  • KMID: 1516877
  • Korean J Nucl Med.
  • 2003 Dec;37(6):418-427.
OBJECTS: 99mTc-lactosylated human serum albumin (LSA) is a newly synthesized radiopharmaceutical that binds to asialoglycoprotein receptors, which are specifically presented on the hepatocyte membrane. Hepatic uptake and blood clearance of...
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Lectin Histochemistry for Effects of N - Nitrosodimethylamine on Glycoconjugates in the Rat Lingual Salivary Glands

Jo UB, Choi YJ, Jo GJ, Park SM

  • KMID: 2283102
  • Korean J Phys Anthropol.
  • 1998 Dec;11(2):281-297.
The effect of NDMA after oral administration (17 mg/ml) on the glycoconjugates of lingual von Ebner's gland and mucous gland were investigated with lectin histochemical methods. For lectin histochemical studies,...
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Cellular Distribution of TGF-beta1 Peptide in Dimethylnitrosamine Induced Fibrosis of Rat Liver

Lee SN, Park DY, Lee SK

  • KMID: 2037292
  • Korean J Pathol.
  • 1997 Nov;31(11):1157-1165.
Recently attention has been focused on the biology of transforming growth factor-beta1 (TGF-beta1). TGF-beta1, a potent regulator of cell proliferation, stimulates the proliferation of many cell types of mesenchymal origin...
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Lack of multi-organ carcinogenesis in female N:GP(S) mice by benzo(a) pyrene, dimethylnitrosamine and dibutylnitrosamine

Lee YS, Cho KJ, Jang JJ

  • KMID: 1742249
  • J Korean Cancer Assoc.
  • 1993 Aug;25(4):572-577.
No abstract available.
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Morphologic Change of Rat Liver Induced by Repeated Administration of Carbon Tetrachloride and Dimethylnitrosamine

Lee TS

Carbon tetrachloride and dimethylnitrosamine, both potent hepatotoxic agents, affect the hepatic lobules with fatty changes and central necrosis, and hemorrhagic necrosis. To study the effects on morphologic changes of the...
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