- Decursinol Angelate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Modulating Type 17 Helper T Cell Responses
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Thapa B, Pak S, Kwon HJ, Lee K
- KMID: 2456221
- Biomol Ther.
- 2019 Sep;27(5):466-473.
- doi: 10.4062/biomolther.2019.004
Angelica gigas has been used as a Korean traditional medicine for pain relief and gynecological health. Although the extracts are reported to have an anti-inflammatory property, the bioactive compounds of... -
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- Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease
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Zhou L, Liu D, Xie Y, Yao X, Li Y
- KMID: 2458527
- Gut Liver.
- 2019 Jul;13(4):430-439.
- doi: 10.5009/gnl18316
BACKGROUND/AIMS: The current study aims to investigate the protective effects of Bifidobacterium infantis on the abnormal immune response to inflammatory bowel disease (IBD) in dextran sodium sulfate (DSS)-induced colitis. METHODS: Eight-week-old... -
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- Baicalein Inhibits Dextran Sulfate Sodium-induced Mouse Colitis
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Zhong X, Surh YJ, Do SG, Shin E, Shim KS, Lee CK, Na HK
- KMID: 2454672
- J Cancer Prev.
- 2019 Jun;24(2):129-138.
- doi: 10.15430/JCP.2019.24.2.129
BACKGROUND: Baicalein is a bioactive flavone that is originally extracted from the root of Scutellaria baicalensis Georgi. This plant has long served as Chinese herbal medicine in the management of... -
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- Colonic Transit Disorder Mediated by Downregulation of Interstitial Cells of Cajal/Anoctamin-1 in Dextran Sodium Sulfate-induced Colitis Mice
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Lu C, Lu H, Huang X, Liu S, Zang J, Li Y, Chen J, Xu W
- KMID: 2449103
- J Neurogastroenterol Motil.
- 2019 Apr;25(2):316-331.
- doi: 10.5056/jnm18173
BACKGROUND/AIMS: Interstitial cells of Cajal (ICC) and their special calcium-activated chloride channel, anoctamin-1 (ANO1) play pivotal roles in regulating colonic transit. This study is designed to investigate the role of... -
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- Anti-inflammatory effects of mulberry twig extracts on dextran sulfate sodium-induced colitis mouse model
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Cui X, Kim E
- KMID: 2444937
- J Nutr Health.
- 2019 Apr;52(2):139-148.
- doi: 10.4163/jnh.2019.52.2.139
PURPOSE: Ulcerative colitis is a common inflammatory bowel disease. Prolonged colitis can be a risk factor for the development of colorectal cancer. Mulberry twig (MT, Sangzhi), a dry branch of... -
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- Characterization of Tetrodes Coated with Au Nanoparticles (AuNPs) and PEDOT and Their Application to Thalamic Neural Signal Detection in vivo
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Lee D, Moon HC, Tran BT, Kwon DH, Kim YH, Jung SD, Joo JH, Park YS
- KMID: 2430114
- Exp Neurobiol.
- 2018 Dec;27(6):593-604.
- doi: 10.5607/en.2018.27.6.593
Tetrodes, consisting of four twisted micro-wires can simultaneously record the number of neurons in the brain. To improve the quality of neuronal activity detection, the tetrode tips should be modified... -
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- From Gut to Brain: Alteration in Inflammation Markers in the Brain of Dextran Sodium Sulfate-induced Colitis Model Mice
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Do J, Woo J
- KMID: 2428972
- Clin Psychopharmacol Neurosci.
- 2018 Nov;16(4):422-433.
- doi: 10.9758/cpn.2018.16.4.422
OBJECTIVE: Neuropsychiatric manifestations like depression and cognitive dysfunction commonly occur in inflammatory bowel disease (IBD). In the context of the brain-gut axis model, colitis can lead to alteration of brain... -
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- Regulatory Dendritic Cells Induced by Mesenchymal Stem Cells Ameliorate Dextran Sodium Sulfate-Induced Chronic Colitis in Mice
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Jo H, Eom YW, Kim HS, Park HJ, Kim HM, Cho MY
- KMID: 2427457
- Gut Liver.
- 2018 Nov;12(6):664-673.
- doi: 10.5009/gnl18072
BACKGROUND/AIMS: Regulatory dendritic cells (rDCs), which can be induced by mesenchymal stem cells (MSCs), play an important role in inducing and maintaining homeostasis of regulatory T cells and exhibit anti-inflammatory... -
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- T Cell-Specific Knockout of STAT3 Ameliorates Dextran Sulfate Sodium-Induced Colitis by Reducing the Inflammatory Response
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Kwon SH, Seo EB, Lee SH, Cho CH, Kim SJ, Kim SJ, Kim HR, Ye SK
- KMID: 2419775
- Immune Netw.
- 2018 Aug;18(4):e30.
- doi: 10.4110/in.2018.18.e30
Signal transducer and activator of transcription 3 (STAT3) has a crucial role in various autoimmune disorders including, inflammatory bowel disease (IBD). Our previous study demonstrated that STAT3 activation by IL-6... -
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- A Protruding Nodule after Filler Injection
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Seok J, Kwon HJ, Park KY, Li K, Shim JH, Seo SJ
- KMID: 2436749
- Korean J Dermatol.
- 2018 Jul;56(6):406-407.
No abstract available. -
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- Adenine attenuates lipopolysaccharide-induced inflammatory reactions
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Silwal P, Lim K, Heo JY, Park JI, Namgung U, Park SK
- KMID: 2414262
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):379-389.
- doi: 10.4196/kjpp.2018.22.4.379
A nucleobase adenine is a fundamental component of nucleic acids and adenine nucleotides. Various biological roles of adenine have been discovered. It is not produced from degradation of adenine nucleotides... -
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- New bulking agent for the treatment of vesicoureteral reflux: Polymethylmethacrylate/dextranomer
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Kim SW, Lee YS, Im YJ, Han SW
- KMID: 2410595
- Investig Clin Urol.
- 2018 May;59(3):206-212.
- doi: 10.4111/icu.2018.59.3.206
PURPOSE: The aim of this study was to report preliminary results of endoscopic treatment of vesicoureteral reflux in children with a single injection of a new bulking agent, cross-linked dextran... -
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- Comparative Effects of Curcumin and Tetrahydrocurcumin on Dextran Sulfate Sodium-induced Colitis and Inflammatory Signaling in Mice
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Yang JY, Zhong X, Kim SJ, Kim DH, Kim HS, Lee JS, Yum HW, Lee J, Na HK, Surh YJ
- KMID: 2416948
- J Cancer Prev.
- 2018 Mar;23(1):18-24.
- doi: 10.15430/JCP.2018.23.1.18
BACKGROUND: Curcumin, a yellow ingredient of turmeric (Curcuma longa Linn, Zingiberaceae), has long been used in traditional folk medicine in the management of inflammatory disorders. Although curcumin has been reported... -
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- Up-regulation of IGF Binding Protein-3 Inhibits Colonic Inflammatory Response
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Kim SC, Hwang PH
- KMID: 2409215
- J Korean Med Sci.
- 2018 Mar;33(13):e110.
- doi: 10.3346/jkms.2018.33.e110
BACKGROUND: The aggravating factors still remained unclear in inflammatory bowel disease (IBD). Despite many different therapeutic approaches, many patients do not respond to the therapy. The anti-inflammatory effect of insulin-like... -
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- Effects of luteolin on chemical induced colon carcinogenesis in high fat diet-fed obese mouse
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Park JE, Kim E
- KMID: 2410321
- J Nutr Health.
- 2018 Feb;51(1):14-22.
- doi: 10.4163/jnh.2018.51.1.14
PURPOSE: Colorectal cancer, which is one of the most commonly diagnosed cancers in developing and developed countries, is highly associated with obesity. The association is largely attributed to changes to... -
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- Substance-P Ameliorates Dextran Sodium Sulfate-Induced Intestinal Damage by Preserving Tissue Barrier Function
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Hwang DY, Kim S, Hong HS
- KMID: 2405968
- Tissue Eng Regen Med.
- 2018 Feb;15(1):63-73.
- doi: 10.1007/s13770-017-0085-7
Intestinal inflammation alters immune responses in the mucosa and destroys colon architecture, leading to serious diseases such as inflammatory bowel disease. Thus, the modulation of intestinal integrity and immune responses... -
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- Dual Effects of High Protein Diet on Mouse Skin and Colonic Inflammation
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Cui X, Kim E
- KMID: 2402343
- Clin Nutr Res.
- 2018 Jan;7(1):56-68.
- doi: 10.7762/cnr.2018.7.1.56
Chronic inflammation is a major etiology of cancer. Accumulating epidemiological and experimental evidences suggest that intake of high protein diet (HPD) is associated with colitis-associated colon cancer, however, most of... -
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- Effect of iron overload with ascorbic acid on experimental colon carcinogenesis in mice
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Ahn TH, Kim SJ, Jeong JH, Nam SY, Yun YW, Lee BJ
- KMID: 2405357
- J Biomed Transl Res.
- 2017 Dec;18(4):136-141.
- doi: 10.12729/jbtr.2017.18.4.136
Excessive iron can promote the production of free radicals, thereby leading to harmful effects on cancer and aging. Ascorbic acid is not only an antioxidant but also a co-factor of... -
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- Poloxamer 407 Hydrogels for Intravesical Instillation to Mouse Bladder: Gel-Forming Capacity and Retention Performance
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Kim SH, Kim SR, Yoon HY, Chang IH, Whang YM, Cho MJ, Kim MJ, Kim SY, Lee SJ, Choi YW
- KMID: 2402601
- Korean J Urol Oncol.
- 2017 Dec;15(3):178-186.
- doi: 10.22465/kjuo.2017.15.3.178
PURPOSE: Poloxamer 407 (P407) thermo-sensitive hydrogel formulations were developed to enhance the retention time in the urinary bladder after intravesical instillation. MATERIALS AND METHODS: P407 hydrogels (P407Gels) containing 0.2 w/w% fluorescein... -
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- The Therapeutic Efficacy of Tonsil-derived Mesenchymal Stem Cells in Dextran Sulfate Sodium-induced Acute Murine Colitis Model
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Song EM, Jung SA, Lee KE, Jang JY, Lee KH, Tae CH, Moon CM, Joo YH, Kim SE, Jung HK, Shim KN
- KMID: 2383421
- Korean J Gastroenterol.
- 2017 Feb;69(2):119-128.
- doi: 10.4166/kjg.2017.69.2.119
BACKGROUND/AIMS: Mesenchymal stem cells (MSCs) are multipotent progenitor cells currently under investigation for its efficacy as the treatment for inflammatory bowel disease. In this study, we evaluated the efficacy of... -
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