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Identification of Molecular Signatures in Mild Intrinsic Atopic Dermatitis by Bioinformatics Analysis

Yin H, Wang S, Gu C

BACKGROUND: Atopic dermatitis (AD) is recognized as a common inflammatory skin disease and frequently occurred in Asian and Black individuals. OBJECTIVE: Since the limitation of dataset associated with human severe AD,...
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Imbalance of Gut Streptococcus, Clostridium, and Akkermansia Determines the Natural Course of Atopic Dermatitis in Infant

Park YM, Lee SY, Kang MJ, Kim BS, Lee MJ, Jung SS, Yoon JS, Cho HJ, Lee E, Yang SI, Seo JH, Kim HB, Suh DI, Shin YH, Kim KW, Ahn K, Hong SJ

PURPOSE: The roles of gut microbiota on the natural course of atopic dermatitis (AD) are not yet fully understood. We investigated whether the composition and function of gut microbiota and...
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Increased Expression of Interleukin-12 in Lesional Skin of Atopic Dermatitis Patients with Psoriasiform Features on Histopathology: An Immunohistochemical Study

Lim HJ, Han MH, Lee EH, Eun DH, Kim JY, Lee WJ, Lee SJ, Kim DW, Park TI, Kim SH, Jang YH

BACKGROUND: Based on clinical and genetic differences, atopic dermatitis (AD) and psoriasis have been classified in two different diseases, but recently, some authors regarded them as in one spectrum. The...
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Phenotypes and endotypes of atopic dermatitis: Clinical implications

Kim M, Kim J

Atopic dermatitis (AD) is the most common chronic inflammatory skin disease, characterized by a complex pathophysiology and a variety of clinical phenotypes. However, heterogeneous clinical phenotypes are generally not considered...
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Antibiotics-Induced Dysbiosis of Intestinal Microbiota Aggravates Atopic Dermatitis in Mice by Altered Short-Chain Fatty Acids

Kim HJ, Lee SH, Hong SJ

PURPOSE: Alterations in the intestinal microbiota in early life affects the development of atopic dermatitis (AD) in humans. This study aimed to further investigate the effects of gut dysbiosis in...
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Urine Malondialdehyde and 8-hydroxydeoxyguanosine Levels as Indices of Oxidative Damage in Patients with Atopic Dermatitis

Choi MW, Kim YS, Lee JH, Han TY

  • KMID: 2465953
  • Korean J Dermatol.
  • 2019 Sep;57(8):457-463.
BACKGROUND: The involvement of oxidative stress in the pathogenesis of various skin diseases has been suggested. OBJECTIVE: Urinary malondialdehyde (MDA) and 8-hydroxydeoxyguanosine (8-OHdG) levels served as indices of oxidative stress. We...
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Profiling of remote skeletal muscle gene changes resulting from stimulation of atopic dermatitis disease in NC/Nga mouse model

Lee D, Seo Y, Kim YW, Kim S, Choi J, Moon SH, Bae H, Kim HS, Kim H, Kim JH, Kim TY, Kim E, Yim S, Lim I, Bang H, Kim JH, Ko JH

Although atopic dermatitis (AD) is known to be a representative skin disorder, it also affects the systemic immune response. In a recent study, myoblasts were shown to be involved in...
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Activated Leukocyte Cell Adhesion Molecule Modulates Th2 Immune Response in Atopic Dermatitis

Oh MS, Hong JY, Kim MN, Kwak EJ, Kim SY, Kim EG, Lee KE, Kim YS, Jee HM, Kim SH, Sol IS, Park CO, Kim KW, Sohn MH

PURPOSE: Activated leukocyte cell adhesion molecule (ALCAM), a member of the immunoglobulin superfamily, is highly expressed on dendritic cells. ALCAM and its receptor CD6 are co-stimulatory molecules in the immunological...
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Interactions Between Atopic Dermatitis and Staphylococcus aureus Infection: Clinical Implications

Kim J, Kim BE, Ahn K, Leung DY

Staphylococcus aureus commonly colonizes the skin of atopic dermatitis (AD) patients and contributes to the development and exacerbation of AD. Multiple factors are associated with colonization of AD skin by...
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Comparison of Clinical Features according to FLG Mutation in Korean Atopic Dermatitis Patients

Lee H, Wang HY, Lee H, Choi EH

  • KMID: 2457686
  • Korean J Dermatol.
  • 2019 Aug;57(7):363-370.
BACKGROUND: Mutation in the gene encoding filaggrin (FLG) is a major predisposing factor for atopic dermatitis (AD), in association with distinct features such as increased allergic sensitization, higher severity, and...
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The Expression of Epidermal Stem Cell Marker and SIRT1 in Atopic Dermatitis: A Discussion of Regenerative Potential

Shin JW, Choi HR, Nam KM, Yang SH, Kim SA, Joe HJ, Hwang YJ, Na JI, Huh CH, Park KC

No abstract available.
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Synergistic Effect of H1-Antihistamines on Topical Corticosteroids for Pruritus in Atopic Dermatitis: A Systematic Review and Meta-Analysis

Hur MS, Choe YB, Ahn KJ, Lee YW

BACKGROUND: Although oral antihistamines (H1-histamine receptor antagonists) are the main treatment option for pruritus in general skin dermatosis, their effect in treating pruritus of atopic dermatitis (AD) has not yet...
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Development of Aspergillus fumigatus-induced chronic atopic dermatitis mouse model

Park A, Park H, Yu J

PURPOSE: Atopic dermatitis (AD) is the most common chronic and relapsing inflammatory skin disease with skin barrier defects and altered immune responses. Chronic inflammation leads to irreversible fibrosis in the...
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Atopic dermatitis mouse models

Kim H

No abstract available.
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Effects of Outdoor Activities in Forests on Atopic Dermatitis

Kim WK, Kim W, Woo JM

BACKGROUND: The aim of this study was to determine the effects of out-door activities in the forest environment, the so-called "forest therapy program," among children with atopic dermatitis (AD). METHODS: A...
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Severe Eczema Herpeticum in an Adult Patient with Atopic Dermatitis Following Herbal Medicine and Acupuncture

Lee H, Lee J, Lim JS, Park HS, Yoon HS, Cho S

  • KMID: 2454376
  • Korean J Dermatol.
  • 2019 Jul;57(6):335-338.
Atopic dermatitis is a common chronic, relapsing skin disorder, and many patients with atopic dermatitis use complementary and alternative medicine instead of consulting a certified dermatologist. Herein, we report the...
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Efficacy and Utility of Wet Wrap Dressing for Patients with Pediatric Atopic Dermatitis

Choi JW, Loh SH, Lew BL, Sim WY

  • KMID: 2454369
  • Korean J Dermatol.
  • 2019 Jul;57(6):301-306.
BACKGROUND: Management of atopic dermatitis (AD) involves the regular use of emollients together with topical steroids or calcineurin inhibitors for acute flares. However, the long-term use of oral medications in...
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Current Status of Patient Education in the Management of Atopic Dermatitis in Korea

Lee MK, Seo JH, Chu H, Kim H, Jang YH, Jeong JW, Yum HY, Han MY, Yoon HJ, Cho SH, Rha YH, Kim JT, Park YL, Seo SJ, Lee KH, Park CO

Patient education is important for successful management of atopic dermatitis; however, due to limited time and resources, patient education remains insufficient. This study aimed to investigate the current state of...
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Combination Effect of Titrated Extract of Centella asiatica and Astaxanthin in a Mouse Model of Phthalic Anhydride-Induced Atopic Dermatitis

Park JH, Yeo IJ, Jang JS, Kim KC, Park MH, Lee HP, Han SB, Hong JT

PURPOSE: In our previous study, we demonstrated that both titrated extract of Centella asiatica (TECA) and astaxanthin (AST) have anti-inflammatory effects in a 5% phthalic anhydride (PA) mouse model of...
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Assessment of relationship between the use of household products and atopic dermatitis in Seoul: focused on products with associated risks

Choi J, Kim J, Kim K

The purpose of this study was to evaluate the relationship between the use of certain household products (HPs) at home and atopic dermatitis (AD) in adults. The study was conducted...
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