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Significance of Secreted Protein Acidic and Rich in Cysteine Expression in Colorectal Carcinoma

Kim YJ

No abstract available.
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Partial Purification and Characterization of a Cysteine Protease Inhibitor from the Plerocercoid of Spirometra erinacei

Chung YB, Yang HJ

Helminthic cysteine proteases are well known to play critical roles in tissue invasion, nutrient uptake, and immune evasion of the parasites. In the same manner, the sparganum, the plerocercoid of...
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N-acetyl-L-cysteine and cysteine increase intracellular calcium concentration in human neutrophils

Hasan MA, Ahn WG, Song DK

N-acetyl-L-cysteine (NAC) and cysteine have been implicated in a number of human neutrophils' functional responses. However, though Ca²⁺ signaling is one of the key signalings contributing to the functional responses...
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Potential role(s) of cysteine cathepsins in cancer progression and metastasis

Lee HR, Choi KC

  • KMID: 2055088
  • J Biomed Res.
  • 2013 Mar;14(1):1-7.
Cancer is the result of damage to the genetic system, i.e., dysfunction of the DNA repair system, resulting in dysregulated expression of various molecules, leading to cancer formation, migration, and...
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Characterization of a cysteine proteinase from adult worms of Paragonimus westermani

Song CY, Kim TS

Paragonimus westermani, the lung fluke, is known to migrate to the pulmonary tissue of mammalian hosts and causes pathological changes in the lungs. An acidic thiol-dependent proteinase with a molecular...
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Activities of different cysteine proteases of Paragonimus westermani in cleaving human IgG

Chung YB, Yang HJ, Kang SY, Kong Y, Cho SY

Cleaving host immunoglobulins is a well known mechanism of evading host immune reactions exploited by helminth parasites. Secreted cysteine proteases of helminth are a part of enzymes cleaving host IgG....
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Effect of Sulfhydryl Compounds on Melanosomal Morphology of Epidermal Melanocytes in UV - Irradiated Black Mice

Han KW, Myung KB, Hahm JH, Kook HI

  • KMID: 2231426
  • Korean J Dermatol.
  • 1987 Oct;25(5):553-561.
The present study was performed to evaluate the effect of sulfhydryl compounds, cysteine and glutathione, on the size of melanosomes and the ratio of melanosormai stages of epidermal melanocytes...
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Purification of a 68-kDa cysteine proteinase from crude extract of Pneumocystis carinii

Choi MH, Chung BS, Chung YB, Yu JR, Cho SR, Hong ST

The present study intended to verify activities of cysteine proteinase of Pneumocystis carinii from rats and to purify the enzyme. In order to exclude the contamination of host-derived enzymes, concentrates...
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Excretory bladder: the source of cysteine proteases in Paragonimus westermani metacercariae

Yang HJ, Chung YB, Kang SY, Kong Y, Cho SY

The cysteine proteases of Paragonimus westermani metacercariae are involved in metacercarial excystment, host immune modulation, and possibly in tissue penetration. In order to clarify the origin of the enzymes, 28...
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Partial characterization of a 17 kDa protein of Clonorchis sinensis

Chung YB, Chung BS, Choi MH, Chai JY, Hong ST

A 17 kDa protein from Clonorchis sinensis adults was purified by a procedure including Sephacryl S-200 HR gel filtration and Q-Sepharose anion exchange chromatography. The protein was proved to be...
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Isolation and characterization of a 40 kDa cysteine protease from Gymnophalloides seoi adult worms

Choi MH, Park WJ, Park YK, Chai JY, Lee SH

A 40 kDa cysteine protease was purified from the crude extract of adult worms of Gymnophalloides seoi by two consecutive steps: Sephacryl S-200 HR and DEAE-Sephacel chromatography. Enzyme activities were...
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Degradations of human immunoglobulins and hemoglobin by a 60 kDa cysteine proteinase of Trichomonas vaginalis

Min DY, Hyun KH, Ryu JS, Ahn MH, Cho MH

The present study was undertaken to investigate the role of cysteine proteinase of Trichomonas vaginalis in escaping from host defense mechanism. A cysteine proteinase of T. vaginalis was purified...
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Cysteine-Added Mutants of Turnip Yellow Mosaic Virus

Shin IS, Kim D, Cho TJ

Native turnip yellow mosaic virus (TYMV) is relatively unreactive to maleimide agents, indicating few reactive thiol groups on TYMV. In the present study, we aimed to construct TYMV mutants that...
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Isolation and partial characterization of cysteine proteinase from sparganum

Song CY, Choi DH, Kim TS, Lee SH

A proteolytic enzyme was purified from the tissue extract of spargana (plerocercoids of Spirometra erinacei) by DEAE-Trisacryl M ion exchange chromatography and thiopropyl-sepharose affinity chromatography resulted in a 21-fold purification....
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The Anticollagenase Effect of Serum in Alkali-burned Cornea in Rabbit

Park DH, Yoon BJ

  • KMID: 1949366
  • J Korean Ophthalmol Soc.
  • 1988 Aug;29(4):511-515.
The possible role of collagenase in the development of corneal ulcers has been intensively studied and collagenase inhibitors have been successfully used to control some corneal ulcers. They are cysteine,...
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Characterization of proteases isolated from Kudoa septempunctata

Shin SP, Zenke K, Yokoyama H

Proteases play important roles in parasite development and host parasite interactions. The protease of Kudoa spp. has been recognized as a key factor of severe proteolysis of fish muscle post-mortem;...
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Caspase-3/CPP32 Immunoreactivity and Its Correlation with Frequency of Apoptotic Bodies in Prostate Adenocarcinoma and Benign Prostatic Hyperplasia

Kang DG, Choi NG

  • KMID: 1884993
  • Korean J Urol.
  • 2001 Jul;42(7):707-712.
PURPOSE: Apoptosis is mediated by apoptosis-specific genes, certain oncogenes and tumor suppressor genes. Caspase-3, a group of cysteine proteases, ier in cases with intermediate (Gleason score 5-7) and high-grade (Gleason...
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Alkali Burns of the Cornea

Youn DH

  • KMID: 1948546
  • J Korean Ophthalmol Soc.
  • 1972 Jun;13(2):59-62.
1. Alkali burns of rabbit corneas were produced by 5.0 N NaOH swabbing the cornea and surrounding sclera. 2. Collagenolytic activity of alkali burned corneas, and the effectiveness of collagenase...
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Partial characterization of a 29 kDa cysteine protease purified from Taenia solium metacestodes

Kim JY, Yang HJ, Kim KS, Chung YB

A 29 kDa cysteine protease of Taenia solium metacestodes was purified by Mono Q anion-exchanger and Superose 6 HR gel filtration chromatography. The enzyme was effectively inhibited by cysteine protease...
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Partial Purification and Properties of a Cysteine Protease from Citrus Red Mite Panonychus citri

Hong SC, Her KH, Kim HU, Lee J, Lee SP, Chung YB

Several studies have reported that the citrus red mites Panonychus citri were an important allergen of citrus-cultivating farmers in Jeju Island. The aim of the present study was to purify...
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