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The Effect of Immobilization Stress and Corticosterone on Haloperidol-induced c-fos Expression in Rat Brain

Yoon JH, Kim KS, Lee KU, Lew TY

  • KMID: 2037062
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):269-275.
OBJECTIVE: Immediate early gene (IEG), c-fos is known to encode a 62 kDa nuclear protein (Fos) which has a critical role in the stimulus response process of many cells. c-fos...
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Hypericum Perforatum Decreased Hippocampus TNF-alpha and Corticosterone Levels with No Effect on Kynurenine/Tryptophan Ratio in Bilateral Ovariectomized Rats

El-Bakly W, Hasanin AH

The present study was designed to investigate the effect Hypericum Perforatum (HP), on behavioral changes, corticosterone, TNF-alpha levels and tryptophan metabolism and disposition in bilateral ovariectomized rats compared to 17alpha...
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Effects of Ginseng Saponin on the Stress-Induced Plasma Corticosterone Levels in Mice

Kim DH, Min SK, Son BK, Lee SK, Song DK

  • KMID: 2340669
  • J Korean Neuropsychiatr Assoc.
  • 2002 May;41(3):389-398.
OBJECTIVES: The present study was designed to investigate the effect of ginseng saponin and its major active metabolite on the HPA axis under acute stress-i.c.v. injection stress, and immobilization stress,...
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Intracerebroventricular Kainic Acid-Induced Damage Affects Blood Glucose Level in d-glucose-fed Mouse Model

Kim CH, Hong JS

We have previously reported that the intracerebroventricular (i.c.v.) administration of kainic acid (KA) results in significant neuronal damage on the hippocampal CA3 region. In this study, we examined possible changes...
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A Case of 17alpha-Hydroxylase Deficiency

Lee YK, Kang YJ, Pak CY, Choi SY, Park MS

  • KMID: 2104264
  • J Korean Pediatr Soc.
  • 1996 Apr;39(4):577-584.
A 12-year-old girl with hypertension, hypokalemia, cystic ovaries and absence of secondary sexual development is presented. Hormonal study revealed very low levels of cortisol, testosterone, estrogen, and high levels of...
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A Case of Primary Amenorrhea due to 17 -Hydroxylase Deficiency

Rim HS, Lee SH, Hong JM, Nam JH, Park HB, An CW, Ki DM, Lim SK, Song YD, Lee HC, Huh KB, Kang IS

  • KMID: 2331163
  • J Korean Soc Endocrinol.
  • 2001 Feb;16(1):130-133.
17 -Hydroxylase deficiency is a rare form of congenital adrenal hyperplasia that is characterized by primary amenorrhea, absence of secondary sex characteristics, hypertension, and a hypokalemic alkalosis that has resulted...
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The Effect of Long-term Immobilization Stress on Spermatogenesis and Testosterone Production

Joo JS, Park K, Ahn KY, Park YI

Purpose: The aim of this study was to investigate the effects of long-term immobilization stress on spermatogenesis and testosterone production in a rat model. Materials and Methods: Thirty randomly selected adult...
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Direct Corticosteroid Modulation of GABAergic Neurons in the Anterior Hypothalamic Area of GAD65-eGFP Mice

Shin SY, Han TH, Lee SY, Han SK, Park JB, Erdelyi F, Szabo G, Ryu PD

Corticosterone is known to modulate GABAergic synaptic transmission in the hypothalamic paraventricular nucleus. However, the underlying receptor mechanisms are largely unknown. In the anterior hypothalamic area (AHA), the sympathoinhibitory center...
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Effect of Sulfonylureas Administered Centrally on the Blood Glucose Level in Immobilization Stress Model

Sharma N, Sim YB, Park SH, Lim SM, Kim SS, Jung JS, Hong JS, Suh HW

Sulfonylureas are widely used as an antidiabetic drug. In the present study, the effects of sulfonylurea administered supraspinally on immobilization stress-induced blood glucose level were studied in ICR mice. Mice...
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Effect of ICV Corticosterone on hypothalamic NPY mRNA Expression in food-restricted, Adrenalectomized Rats

Kim YJ, Kim MR, Nam MS, Kim YS

  • KMID: 2142201
  • J Korean Soc Endocrinol.
  • 1998 Jun;13(2):150-155.
BACKGROUND: Adrenalectomy does impair the expression of hypothalamic NPY gene in the rat and replacement of glucocorticoid by intracerebroventricular(ICV) route resulted in a normalization of refeeding hyperphagia and weight gain...
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Effects of oropharyngeal taste stimuli in the restoration of the fasting-induced activation of the HPA axis in rats

Yoo SB, Lee JH, Ryu V, Jahng JW

INTRODUCTION: This study examined the regulatory mechanism underlying the meal-induced changes in the hypothalamic-pituitary-adrenal gland (HPA) axis activity. MATERIALS AND METHODS: Male Sprague-Dawley rats (250-300 g) were hired for two different...
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Alterations in Spontaneous Movement, Corticosterone, and Cytokines in Mice Exposed to 835 MHz Radiofrequency Radiation

Lee MS, Oh CS, Ryu JH, Lee JK, Kim MJ

Although commercialization of mobile phones has raised much concerns about the effects of radiofrequency radiation on the human body, few experimental studies have been conducted on the effects of radiofrequency...
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Effect of Sleep Deprivation on the Male Reproductive System in Rats

Choi JH, Lee SH, Bae JH, Shim JS, Park HS, Kim YS, Shin C

There has been no study reporting on the influence of sleep deprivation on the male reproductive system including sperm quality. In this study, we hypothesized that sleep deprivation could lead...
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Estrogen modulates transactivations of SXR-mediated liver X receptor response element and CAR-mediated phenobarbital response element in HepG2 cells

Min G

The nuclear receptors, steroid and xenobiotic receptor (SXR) and constitutive androstane receptor (CAR) play important functions in mediating lipid and drug metabolism in the liver. The present study demonstrates modulatory...
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Effect of Beta-Asarone on Impairment of Spatial Working Memory and Apoptosis in the Hippocampus of Rats Exposed to Chronic Corticosterone Administration

Lee B, Sur B, Cho SG, Yeom M, Shim I, Lee H, Hahm DH

beta-asarone (BAS) is an active component of Acori graminei rhizoma, a traditional medicine used clinically in treating dementia and chronic stress in Korea. However, the cognitive effects of BAS and...
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Effects of hypothyroidism on cell proliferation and neuroblasts in the hippocampal dentate gyrus in a rat model of type 2 diabetes

Yi SS, Hwang IK, Choi JW, Won MH, Seong JK, Yoon YS

We observed how the hypothyroid state affects diabetic states and modifies cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus (DG). For this, 0.03% methimazole, an anti-thyroid drug, was...
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Intranasal Administration of Oxytocin Attenuates Stress Responses Following Chronic Complicated Stress in Rats

Yang Y, Yu H, Babygirija R, Shi B, Sun W, Zheng X, Zheng J

  • KMID: 2460490
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):611-622.
  • doi: 10.5056/jnm19065
BACKGROUND/AIMS: Gastrointestinal (GI) symptoms may develop when we fail to adapt to various stressors of our daily life. Central oxytocin (OXT) can counteract the biological actions of corticotropin-releasing factor (CRF),...
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Chronic Early-life Stress in Rat Pups Alters Basal Corticosterone, Intestinal Permeability, and Fecal Microbiota at Weaning: Influence of Sex

Moussaoui , Jacobs JP, Larauche M, Biraud M, Million M, Mayer E, Taché Y

  • KMID: 2367465
  • J Neurogastroenterol Motil.
  • 2017 Jan;23(1):135-143.
  • doi: 10.5056/jnm16105
BACKGROUND/AIMS: Wistar rat dams exposed to limited nesting stress (LNS) from post-natal days (PND) 2 to 10 display erratic maternal behavior, and their pups show delayed maturation of the hypothalamic-pituitary-adrenal...
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Effects of Chronic Restraint Stress on Body Weight, Food Intake, and Hypothalamic Gene Expressions in Mice

Jeong JY, Lee DH, Kang SS

BACKGROUND: Stress affects body weight and food intake, but the underlying mechanisms are not well understood. METHODS: We evaluated the changes in body weight and food intake of ICR male mice...
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A case of male Pseudohermaphroditism due to 17alpha-Hydroxylase Deficiency

Kim JH, Choi SY, Kim JH, Kim JH, Rha JG, Kang CS

  • KMID: 2260800
  • Korean J Obstet Gynecol.
  • 1997 Apr;40(4):896-901.
A 21-year-old phenotypic female with 46,XY genotype presented with primary amenorrhea, headache, absence of secondary sex characteristics, and hypertension.Further evaluation confirmed male pseudohermaphroditism having no nterus and adnexase.After basic hormonal...
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