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Protective Role of Corticosterone against Hydrogen Peroxide-Induced Neuronal Cell Death in SH-SY5Y Cells

Lee C, Jang JH, Park GH

Stress breaks body balance, which can cause diverse physiological disorders and worsen preexisting diseases. However, recent studies have reported that controllable stress and overcoming from stress reinforce resilience to resist...
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Intranasal Administration of Oxytocin Attenuates Stress Responses Following Chronic Complicated Stress in Rats

Yang Y, Yu H, Babygirija R, Shi B, Sun W, Zheng X, Zheng J

  • KMID: 2460490
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):611-622.
  • doi: 10.5056/jnm19065
BACKGROUND/AIMS: Gastrointestinal (GI) symptoms may develop when we fail to adapt to various stressors of our daily life. Central oxytocin (OXT) can counteract the biological actions of corticotropin-releasing factor (CRF),...
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Alterations in Spontaneous Movement, Corticosterone, and Cytokines in Mice Exposed to 835 MHz Radiofrequency Radiation

Lee MS, Oh CS, Ryu JH, Lee JK, Kim MJ

Although commercialization of mobile phones has raised much concerns about the effects of radiofrequency radiation on the human body, few experimental studies have been conducted on the effects of radiofrequency...
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Protein Kinase C Mediates the Corticosterone-induced Sensitization of Dorsal Root Ganglion Neurons Innervating the Rat Stomach

Li M, Xue L, Zhu HY, Wang H, Xu X, Zhang PA, Wu G, Xu GY

  • KMID: 2387838
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):464-476.
  • doi: 10.5056/jnm16161
BACKGROUND/AIMS: Gastric hypersensitivity contributes to abdominal pain in patients with functional dyspepsia. Recent studies showed that hormones induced by stress are correlated with visceral hypersensitivity. However, the precise mechanisms underlying...
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Chronic Early-life Stress in Rat Pups Alters Basal Corticosterone, Intestinal Permeability, and Fecal Microbiota at Weaning: Influence of Sex

Moussaoui , Jacobs JP, Larauche M, Biraud M, Million M, Mayer E, Taché Y

  • KMID: 2367465
  • J Neurogastroenterol Motil.
  • 2017 Jan;23(1):135-143.
  • doi: 10.5056/jnm16105
BACKGROUND/AIMS: Wistar rat dams exposed to limited nesting stress (LNS) from post-natal days (PND) 2 to 10 display erratic maternal behavior, and their pups show delayed maturation of the hypothalamic-pituitary-adrenal...
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Effect of Sleep Deprivation on the Male Reproductive System in Rats

Choi JH, Lee SH, Bae JH, Shim JS, Park HS, Kim YS, Shin C

There has been no study reporting on the influence of sleep deprivation on the male reproductive system including sperm quality. In this study, we hypothesized that sleep deprivation could lead...
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Effect of Beta-Asarone on Impairment of Spatial Working Memory and Apoptosis in the Hippocampus of Rats Exposed to Chronic Corticosterone Administration

Lee B, Sur B, Cho SG, Yeom M, Shim I, Lee H, Hahm DH

beta-asarone (BAS) is an active component of Acori graminei rhizoma, a traditional medicine used clinically in treating dementia and chronic stress in Korea. However, the cognitive effects of BAS and...
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Effects of Electromagnetic Radiation Exposure on Stress-Related Behaviors and Stress Hormones in Male Wistar Rats

Mahdavi SM, Sahraei H, Yaghmaei P, Tavakoli H

Studies have demonstrated that electromagnetic waves, as the one of the most important physical factors, may alter cognitive and non-cognitive behaviors, depending on the frequency and energy. Moreover, non-ionizing radiation...
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Hypericum Perforatum Decreased Hippocampus TNF-alpha and Corticosterone Levels with No Effect on Kynurenine/Tryptophan Ratio in Bilateral Ovariectomized Rats

El-Bakly W, Hasanin AH

The present study was designed to investigate the effect Hypericum Perforatum (HP), on behavioral changes, corticosterone, TNF-alpha levels and tryptophan metabolism and disposition in bilateral ovariectomized rats compared to 17alpha...
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Alpha-Asarone, a Major Component of Acorus gramineus, Attenuates Corticosterone-Induced Anxiety-Like Behaviours via Modulating TrkB Signaling Process

Lee B, Sur B, Yeom M, Shim I, Lee H, Hahm DH

We investigated the anxiolytic-like activity of alpha-asarone (AAS) from Acorus gramineus in an experimental rat model of anxiety induced by repeated administration of the exogenous stress hormone corticosterone (CORT). The...
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Chronic Administration of Catechin Decreases Depression and Anxiety-Like Behaviors in a Rat Model Using Chronic Corticosterone Injections

Lee B, Sur B, Kwon S, Yeom M, Shim I, Lee H, Hahm DH

  • KMID: 2170678
  • Biomol Ther.
  • 2013 Jul;21(4):313-322.
Previous studies have demonstrated that repeated administration of the exogenous stress hormone corticosterone (CORT) induces dysregulation in the hypothalamic-pituitary-adrenal (HPA) axis and results in depression and anxiety. The current study...
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Acute Stress and Chronic Stress Change Brain-Derived Neurotrophic Factor (BDNF) and Tyrosine Kinase-Coupled Receptor (TrkB) Expression in Both Young and Aged Rat Hippocampus

Shi SS, Shao SH, Yuan BP, Pan F, Li ZL

PURPOSE: The purpose of this study is to explore the dynamic change of brain-derived neurotrophic factor (BDNF) mRNA, protein, and tyrosine kinase-coupled receptor (TrkB) mRNA of the rat hippocampus under...
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Chronic Administration of Monosodium Glutamate under Chronic Variable Stress Impaired Hypothalamic-Pituitary-Adrenal Axis Function in Rats

Seo HJ, Ham HD, Jin HY, Lee WH, Hwang HS, Park SA, Kim YS, Choi SC, Lee S, Oh KJ, Kim BS, Park BR, Lee MY

The hypothalamic-pituitary-adrenal (HPA) axis is the primary endocrine system to respond to stress. The HPA axis may be affected by increased level of corticotrophin-releasing factors under chronic stress and by...
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The Effect of Immobilization Stress and Corticosterone on Haloperidol-induced c-fos Expression in Rat Brain

Yoon JH, Kim KS, Lee KU, Lew TY

  • KMID: 2037062
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):269-275.
OBJECTIVE: Immediate early gene (IEG), c-fos is known to encode a 62 kDa nuclear protein (Fos) which has a critical role in the stimulus response process of many cells. c-fos...
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Effects of Ginseng Saponin on the Stress-Induced Plasma Corticosterone Levels in Mice

Kim DH, Min SK, Son BK, Lee SK, Song DK

  • KMID: 2340669
  • J Korean Neuropsychiatr Assoc.
  • 2002 May;41(3):389-398.
OBJECTIVES: The present study was designed to investigate the effect of ginseng saponin and its major active metabolite on the HPA axis under acute stress-i.c.v. injection stress, and immobilization stress,...
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