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Beneficial Effect of Cordyceps militaris on Exercise Performance via Promoting Cellular Energy Production

Choi E, Oh J, Sung GH

Cordyceps militaris has been reported to the diverse pharmaceutical effects including cancer, inflammatory diseases, and bacteria or virus infection. However, the effect of C. militaris on exercise performance has not...
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Antithrombotic and Antiplatelet Effects of Cordyceps militaris

Choi E, Oh J, Sung GH

Cordyceps is a genus of ascomycete fungi and is well known as one of the important medical fungi in Chinese, Korea, and other Asian countries, because of its various beneficial...
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Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro

He MT, Lee AY, Park CH, Cho EJ

BACKGROUND/OBJECTIVES: Excessive production of reactive oxygen species (ROS) such as hydroxyl (·OH), nitric oxide (NO), and hydrogen peroxide (H2O2) is reported to induce oxidative stress. ROS generated by oxidative stress...
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Effects of Cordyceps militaris supplementation on the immune response and upper respiratory infection in healthy adults: a randomized, double-blind, placebo-controlled study

Jung SJ, Hwang JH, Oh MR, Chae SW

PURPOSE: Upper respiratory tract infections are major causes of the common cold throughout the world. Cordyceps militaris (C. militaris) is a well-known functional food for its anti-fatigue and immunomodulating activities....
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Scratching Stimuli of Mycelia Influence Fruiting Body Production and ROS-Scavenging Gene Expression of Cordyceps militaris

Liu GQ, Qiu XH, Cao L, Han RC

The entomopathogenic fungus Cordyceps militaris is a valuable medicinal ascomycete, which degenerates frequently during subsequent culture. To avoid economic losses during industrialized production, scratching stimuli of mycelia was introduced to...
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Increased glucose metabolism and alpha-glucosidase inhibition in Cordyceps militaris water extract-treated HepG2 cells

Kim DJ, Kang YH, Kim KK, Kim TW, Park JB, Choe M

BACKGROUND/OBJECTIVES: Recent living condition improvements, changes in dietary habits, and reductions in physical activity are contributing to an increase in metabolic syndrome symptoms including diabetes and obesity. Through such societal...
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Development of High Cordycepin-Producing Cordyceps militaris Strains

Kang N, Lee HH, Park I, Seo YS

Cordyceps militaris, known as Dong-Chong-Xia-Cao, produces the most cordycepin among Cordyceps species and can be cultured artificially. For these reasons, C. militaris is widely used as herb or functional food...
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Identification of the Genes Involved in the Fruiting Body Production and Cordycepin Formation of Cordyceps militaris Fungus

Zheng ZL, Qiu XH, Han RC

A mutant library of Cordyceps militaris was constructed by improved Agrobacterium tumefaciens-mediated transformation and screened for degradation features. Six mutants with altered characters in in vitro and in vivo fruiting...
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Cordyceps militaris alleviates non-alcoholic fatty liver disease in ob/ob mice

Choi HN, Jang YH, Kim MJ, Seo MJ, Kang BW, Jeong YK, Kim JI

  • KMID: 2313726
  • Nutr Res Pract.
  • 2014 Apr;8(2):172-176.
BACKGROUND/OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is becoming an important public health problem as metabolic syndrome and type 2 diabetes have become epidemic. In this study we investigated the protective...
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Fruiting Body Formation of Cordyceps militaris from Multi-Ascospore Isolates and Their Single Ascospore Progeny Strains

Shrestha B, Han SK, Sung JM, Sung GH

Interest in commercial cultivation and product development of Cordyceps species has shown a recent increase. Due to its biochemical and pharmacological effects, Cordyceps militaris, commonly known as orange caterpillar fungus,...
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Cordyceps militaris Enhances MHC-restricted Antigen Presentation via the Induced Expression of MHC Molecules and Production of Cytokines

Shin S, Park Y, Kim S, Oh HE, Ko YW, Han S, Lee S, Lee CK, Cho K, Kim K

BACKGROUND: Cordyceps militarys water extract (CME) has been reported to exert antitumor and immunomodulatory activities in vivo and in vitro. However, the therapeutic mechanism has not yet been elucidated. In...
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Fruit Body Formation on Silkworm by Cordyceps militaris

Hong IP, Kang PD, Kim KY, Nam SH, Lee MY, Choi YS, Kim NS, Kim HK, Lee KG, Humber RA

  • KMID: 2312579
  • Mycobiology.
  • 2010 Jun;38(2):128-132.
Injection inoculation protocols for fruit body formation of Cordyceps militaris (C. militaris) were investigated to improve the incidence of infection in the silkworm species Bombyx mori (B. mori). Injection, with...
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Immunostimulatory Effects of Cordyceps militaris on Macrophages through the Enhanced Production of Cytokines via the Activation of NF-kappaB

Shin S, Kwon J, Lee S, Kong H, Lee S, Lee CK, Cho K, Ha NJ, Kim K

BACKGROUND: Cordyceps militaris has been used in traditional medicine to treat numerous diseases and has been reported to possess both antitumor and immunomodulatory activities in vitro and in vivo. However,...
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The Anti-inflammatory Effects of Water Extract from Cordyceps militaris in Murine Macrophage

Jo WS, Choi YJ, Kim HJ, Lee JY, Nam BH, Lee JD, Lee SW, Seo SY, Jeong MH

  • KMID: 2312563
  • Mycobiology.
  • 2010 Mar;38(1):46-51.
The aim of this study was to determine the in vitro anti-inflammatory effect of hot water extract from Cordyceps militaris fruiting bodies (CMWE) on lipopolysaccharide (LPS)-stimulated nitric oxide (NO) production,...
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Antifungal and Anticancer Activities of a Protein from the Mushroom Cordyceps militaris

Park BT, Na KH, Jung EC, Park JW, Kim HH

The mushroom Cordyceps militaris has been used for a long time in eastern Asia as a nutraceutical and in traditional Chinese medicine as a treatment for cancer patients. In the...
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Chemical Ingredients of Cordyceps militaris

Hur H

Medicinal mushrooms, including Cordyceps militaris, have received attention in Korea because of their biological activities. In the fruiting body and in corpus of C. militaris, the total free amino acid...
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Activation of Macrophages by the Components Produced from Cordyceps militaris

Kim H, Kim K, Han S, Lee S, Kwon J, Lee S, Kim K

BACKGROUND: Cordyceps militaris have been reported to modify the immune and inflammatory responses both in vivo and in vitro. Macrophages play important roles in the innate immunity through the phagocytosis...
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Effect of Preservation Periods and Subcultures on Fruiting Body Formation of Cordyceps militaris In Vitro

Sung JM, Park YJ, Lee JO, Han SK, Lee WH, Choi SK, Shrestha B

  • KMID: 2312495
  • Mycobiology.
  • 2006 Dec;34(4):196-199.
Effects of various preservation periods and subcultures on fruiting body formation of Cordyceps militaris were investigated using EFCC C-10995 single ascospore strains. Fruiting body formation by original strains was profuse...
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Selection of Superior Strains of Cordyceps militaris with Enhanced Fruiting Body Productivity

Sung JM, Park YJ, Lee JO, Han SK, Lee WH, Choi SK, Shrestha B

In vitro fruiting bodies were produced from ten different isolates of Cordyceps militaris EFCC C-5736, EFCC C-5941, EFCC C-5976, EFCC C-6040, EFCC C-6849, EFCC C-7268, EFCC C-7342, EFCC C-7992, EFCC...
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Observations on Some of the Mycelial Growth and Pigmentation Characteristics of Cordyceps militaris Isolates

Shrestha B, Lee WH, Han SK, Sung JM

  • KMID: 2312484
  • Mycobiology.
  • 2006 Jun;34(2):83-91.
Characteristic growth patterns of Cordyceps militaris isolates on various media, under varying light conditions and at varying incubation periods were examined. Light was found to be the most critical single...
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