- Comparison of long-term outcomes of colonic stenting as a “bridge to surgery” and emergency surgery in patients with left-sided malignant colonic obstruction
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Khomvilai S, Pattarajierapan S
- KMID: 2539711
- Ann Coloproctol.
- 2023 Feb;39(1):17-26.
- doi: 10.3393/ac.2021.00227.0032
Purpose: Long-term oncologic outcomes of colonic stenting as a “bridge to surgery” in patients with left-sided malignant colonic obstruction (LMCO) are unclear. This study was performed to compare long-term outcomes... -
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- Epigallocatechin-3-gallate suppresses hemin-aggravated colon carcinogenesis through Nrf2-inhibited mitochondrial reactive oxygen species accumulation
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Seok JH, Kim DH, Kim HJ, Jo HH, Kim EY, Jeong JH, Park YS, Lee SH, Kim DJ, Nam SY, Lee BJ, Lee HJ
- KMID: 2533378
- J Vet Sci.
- 2022 Sep;23(5):e74.
- doi: 10.4142/jvs.22097
Background: Previous studies have presented evidence to support the significant association between red meat intake and colon cancer, suggesting that heme iron plays a key role in colon carcinogenesis. Epigallocatechin-3-gallate... -
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- Comparative Study of Autophagy in Oxaliplatin-Sensitive and Resistant SNU-C5 Colon Cancer Cells
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Boo SJ, Piao MJ, Kang KA, Zhen AX, Fernando PDSM, Herath HMUL, Lee SJ, Song SE, Hyun JW
- KMID: 2532877
- Biomol Ther.
- 2022 Sep;30(5):447-454.
- doi: 10.4062/biomolther.2022.028
Few studies have evaluated the role of autophagy in the development of oxaliplatin (OXT) resistance in colon cancer cells. In this study, we compared the role of autophagy between SNU-C5... -
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- Characterization of KRC-108 as a TrkA Kinase Inhibitor with Anti-Tumor Effects
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Lee HJ, Moon Y, Choi J, Heo JD, Kim S, Nallapaneni HK, Chin YW, Lee J, Han SY
- KMID: 2531001
- Biomol Ther.
- 2022 Jul;30(4):360-367.
- doi: 10.4062/biomolther.2021.195
Tropomyosin receptor kinase A (TrkA) protein is a receptor tyrosine kinase encoded by the NTRK1 gene. TrkA signaling mediates the proliferation, differentiation, and survival of neurons and other cells following... -
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- Clinical implication of adjuvant chemotherapy according to mismatch repair status in patients with intermediate-risk stage II colon cancer: a retrospective study
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Kang BW, Baek DW, Chang E, Kim HJ, Park SY, Park JS, Choi GS, Baek JH, Kim JG
- KMID: 2529272
- J Yeungnam Med Sci.
- 2022 Apr;39(2):141-149.
- doi: 10.12701/yujm.2021.01571
Background: The present study evaluated the clinical implications of adjuvant chemotherapy according to the mismatch repair (MMR) status and clinicopathologic features of patients with intermediate- and high-risk stage II colon... -
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- Natural Compound Shikonin Induces Apoptosis and Attenuates Epithelial to Mesenchymal Transition in Radiation-Resistant Human Colon Cancer Cells
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Shilnikova K, Piao MJ, Kang KA, Madushan Fernando PDS, Lakmini Herath HMU, Cho SJ, Hyun JW
- KMID: 2526815
- Biomol Ther.
- 2022 Mar;30(2):137-144.
- doi: 10.4062/biomolther.2021.088
Radiation resistance represents an imperative obstacle in the treatment of patients with colorectal cancer, which remains difficult to overcome. Here, we explored the anti-proliferative and migration-inhibiting properties of the natural... -
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- Clinical relevance and prognostic role of preoperative cell-free single-stranded DNA concentrations in colorectal cancer patients
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Song HS, Kang DH, Kim H, Ahn TS, Kim TW, Baek MJ
- KMID: 2524518
- Korean J Clin Oncol.
- 2021 Dec;17(2):59-67.
- doi: 10.14216/kjco.21010
Purpose: Circulating cell-free single-stranded DNA (ccf-ssDNA) is extracellular DNA and it is a useful biomarker for the diagnosis of tumors and predicting the prognosis of tumors. However, the clinical usefulness... -
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- Postoperative Clinical Outcomes of Colonic Stent Placement as Bridge-to-surgery vs. Emergency Surgery in Left-sided Malignant Colonic Obstruction
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Choe EJ, Lee YK, Jeon HH, Choi JW, Park BK, Won SY, Seo JH, Lee CK, Cho YS
- KMID: 2522866
- J Dig Cancer Res.
- 2021 Dec;9(2):43-49.
- doi: 10.52927/jdcr.2021.9.2.43
Background/Aims: Colonic stenting as a bridge to elective surgery is an alternative for emergency surgery in patients with acute malignant colonic obstruction. However, since its benefits are uncertain, we aimed... -
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- Comparison of cisplatin-induced anti-tumor response in CT26 syngeneic tumors of three BALB/c substrains
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Gong JE, Jin YJ, Kim JE, Choi YJ, Lee SJ, Kim KS, Jung YS, Cho JY, Lim Y, Kang HG, Hwang DY
- KMID: 2523775
- Lab Anim Res.
- 2021 Dec;37(4):307-319.
- doi: 10.1186/s42826-021-00110-3
Background: To determine whether the background of BALB/c substrains affects the response to anti-tumor drugs, we measured for alterations in tumor growth, histopathological structure of the tumor, and expressions of... -
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- Short- and long-term outcomes of laparoscopic segmental left colectomy for splenic flexure colon cancer: comparison with propensity score matching
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Kim MJ, Kim JH, Lee YS, Kye BH, Cho HM, Kim HJ, Kang WK
- KMID: 2521849
- Ann Surg Treat Res.
- 2021 Nov;101(5):274-280.
- doi: 10.4174/astr.2021.101.5.274
Purpose: Splenic flexure colon cancer (SFCC) is a rare disease that accounts for 2%–8% of colorectal cancers, and the extent of surgery and resection is still debatable. There have also... -
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- Podophyllotoxin Induces ROS-Mediated Apoptosis and Cell Cycle Arrest in Human Colorectal Cancer Cells via p38 MAPK Signaling
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Lee SO, Joo SH, Kwak AW, Lee MH, Seo JH, Cho SS, Yoon G, Chae JI, Shim JH
- KMID: 2522254
- Biomol Ther.
- 2021 Nov;29(6):658-666.
- doi: 10.4062/biomolther.2021.143
Podophyllotoxin (PT), a lignan compound from the roots and rhizomes of Podophyllum peltatum, has diverse pharmacological activities including anticancer effect in several types of cancer. The molecular mechanism of the... -
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- The Prognosis and Recurrence Pattern of Right- and Left-Sided Colon Cancer in Stage II, Stage III, and Liver Metastasis After Curative Resection
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Nakamura Y, Hokuto D, Koyama F, Matsuo Y, Nomi T, Yoshikawa T, Kamitani N, Sadamitsu T, Takei T, Matsumoto Y, Iwasa Y, Fukuoka K, Obara S, Nakamoto T, Kuge H, Sho M
- KMID: 2521903
- Ann Coloproctol.
- 2021 Oct;37(5):326-336.
- doi: 10.3393/ac.2020.09.14
Purpose: Primary tumor location of colon cancer has been reported to affect the prognosis after curative resection. However, some reports suggested the impact was varied by tumor stage. This study... -
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- Current Status of Colorectal Cancer and Its Public Health Burden in Thailand
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Tiankanon K, Aniwan S, Rerknimitr R
- KMID: 2518852
- Clin Endosc.
- 2021 Jul;54(4):499-504.
- doi: 10.5946/ce.2020.245-IDEN
Colorectal cancer (CRC) accounts for approximately 10.3% of new cancer cases in Thailand and is currently the 3rd most prevalent cancer found among the Thai population. Starting in 2017, the... -
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- Vinpocetine inhibits the proliferation and induces apoptosis in human colon cancer cells
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Kim MK, Park HJ, Kim Y, Kim YI, Bae SK, Kim HJ, Bae MK
- KMID: 2514824
- Int J Oral Biol.
- 2021 Mar;46(1):7-14.
- doi: 10.11620/IJOB.2021.46.1.7
Vinpocetine induces anti-inflammatory effects in various inflammatory diseases via the inhibition of phosphodiesterase type-1-independent nuclear factor-κB signaling pathway and the release of inflammatory cytokines. In this study, we investigated the... -
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- Nuclear Factor Erythroid 2-related Factor 2 Knockout Suppresses the Development of Aggressive Colorectal Cancer Formation Induced by Azoxymethane/Dextran Sulfate Sodium-Treatment in Female Mice
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Song CH, Kim N, Nam RH, Choi SI, Kang C, Jang JY, Nho H, Shin E, Lee HN
- KMID: 2514694
- J Cancer Prev.
- 2021 Mar;26(1):41-53.
- doi: 10.15430/JCP.2021.26.1.41
Colon tumors develop more frequently in male than in female. Nuclear factor erythroid 2-related factor 2 (Nrf2) plays differential roles in the stage of tumorigenesis. The purpose of this study... -
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- Effect of ascorbic acid and hemin on experimental colon carcinogenesis in mice
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Jeong YS, Kim EY, Jeong JH, Nam SY, Lee BJ
- KMID: 2510283
- J Biomed Transl Res.
- 2020 Dec;21(4):177-183.
- doi: 10.12729/jbtr.2020.21.4.177
Colon cancer is known as the third most widespread cancer in the world. The interaction of heme-iron and ascorbic acid (AA) in colon carcinogenesis is not evident. Hemin (ferric chloride heme)... -
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- Laparoscopic Treatment of Colonic Intussusception Caused by Sigmoid Colon Cancer
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Kwak HY, Kim MS, Park JW, Kim DH, Lee JH, Chang YS
- KMID: 2506462
- J Minim Invasive Surg.
- 2020 Sep;23(3):149-151.
- doi: 10.7602/jmis.2020.23.3.149
Reports on the laparoscopic treatment for colonic intussusception are exceedingly rare. We report a case of colonic intussusception caused by sigmoid colon cancer which was treated with a laparoscopic approach.... -
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- Laparoscopic Repair for Enterocutaneous Fistula Caused by Laparoscopic Right Hemicolectomy for Pan-Peritonitis due to Cecal Cancer Perforation
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Lee MH, Kim MG
- KMID: 2506461
- J Minim Invasive Surg.
- 2020 Sep;23(3):144-148.
- doi: 10.7602/jmis.2020.23.3.144
Enterocutaneous fistula (ECF) can occur after any intra-abdominal procedure and is a concern for most surgeons. We report a case of laparoscopic treatment of an ECF in a 65-year-old male... -
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- Anti-Proliferative Activity of Nodosin, a Diterpenoid from Isodon serra, via Regulation of Wnt/β-Catenin Signaling Pathways in Human Colon Cancer Cells
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Bae ES, Kim YM, Kim DH, Byun WS, Park HJ, Chin YW, Lee SK
- KMID: 2505692
- Biomol Ther.
- 2020 Sep;28(5):465-472.
- doi: 10.4062/biomolther.2020.003
Colorectal cancer (CRC) is one of the most malignant type of cancers and its incidence is steadily increasing, due to life style factors that include western diet. Abnormal activation of... -
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- Bilateral Infectious Keratitis Caused by Pseudomonas aeruginosa in a Colon Cancer Patient
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Kim HY, Jang SG, Lee JS
- KMID: 2504324
- J Korean Ophthalmol Soc.
- 2020 Jul;61(7):819-822.
- doi: 10.3341/jkos.2020.61.7.819
Purpose: To report a case of successful treatment of bilateral infectious keratitis combined with endophthalmitis caused by Pseudomonas aeruginosa in an immunocompromised patient. Case summary: A 66-year-old male with colon cancer... -
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