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Diagnosis of hepatocellular carcinoma: Which MRI contrast agent? Which diagnostic criteria?

Kim SY

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Macro-aspartate aminotransferase in a healthy woman

Lorubbio M, Ognibene A, Salvadori B, Fanelli A, Laffi G

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Optimal sequence of systemic therapy after sorafenib failure in patients with hepatocellular carcinoma

Han S, Kim DY

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Is tenofovir and entecavir combination therapy still the optimal treatment for chronic hepatitis B patients with prior suboptimal response?

Jang BK

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How does low-level viremia affect the prognosis of patients with chronic hepatitis B?

Lee HW, Kim BK

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Is liver biopsy still useful in the era of non-invasive tests?

Lim TS, Kim JK

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Low-level viremia in patients undergoing antiviral therapy: Does it indicate time for a change?

Kim JH, Sinn DH

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Role of cytoglobin, a novel radical scavenger, in stellate cell activation and hepatic fibrosis

Thuy LTT, Hai H, Kawada N

Cytoglobin (Cygb), a stellate cell-specific globin, has recently drawn attention due to its association with liver fibrosis. In the livers of both humans and rodents, Cygb is expressed only in...
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Management of liver diseases during the pandemic of coronavirus disease-19

Cho JY, Kim SS, Lee YS, Song DS, Lee JH, Kim JH, Korean Association for the Study of the Liver

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Fecal microbiota transplantation in alcohol related liver diseases

Shasthry SM

The current standard of care for severe alcoholic hepatitis (SAH) has several limitations in that only up to one-third of patients are eligible for steroid therapy. Additionally, steroids have their...
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Novel biomarkers for the management of chronic hepatitis B

Inoue T, Tanaka Y

Hepatitis B virus (HBV) cannot be eliminated completely from infected hepatocytes because of the presence of intrahepatic covalently closed circular DNA (cccDNA). As chronic hepatitis B (CHB) can progress to...
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Clinical application of ultrasonography-guided percutaneous liver biopsy and its safety over 18 years

Chang Y, Kim JI, Lee B, Kim SG, Jung MJ, Kim YS, Jeong SW, Jang JY, Yoo JJ

Background/Aims: Liver biopsy (LB) remains the gold standard for the evaluation of liver disease. However, over the past two decades, many noninvasive tests have been developed and utilized in clinical...
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Unmet needs of chronic hepatitis C in the era of direct-acting antiviral therapy

Huang CF, Yu ML

The treatment of chronic hepatitis C (CHC) has been revolutionized in an era of all-oral direct-acting antivirals (DAAs) since 2014. Satisfactory treatment efficacy and tolerability can be provided by novel...
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Effectiveness of nivolumab versus regorafenib in hepatocellular carcinoma patients who failed sorafenib treatment

Lee CH, Lee YB, Kim MA, Jang H, Oh H, Kim SW, Cho EJ, Lee KH, Lee JH, Yu SJ, Yoon JH, Kim TY, Kim YJ

Background/Aims: Several treatment options are currently available for patients with hepatocellular carcinoma (HCC) failing previous sorafenib treatment. We aimed to compare the effectiveness of regorafenib and nivolumab in these patients. Methods:...
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Low-level viremia and cirrhotic complications in patients with chronic hepatitis B according to adherence to entecavir

Lee SB, Jeong J, Park JH, Jung SW, Jeong ID, Bang SJ, Shin JW, Park BR, Park EJ, Park NH

Background/Aims: Low-level viremia (LLV) after nucleos(t)ide analog treatment was presented as a possible cause of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). However, detailed information on patients’...
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Comparison of LI-RADS 2018 and KLCA-NCC 2018 for noninvasive diagnosis of hepatocellular carcinoma using magnetic resonance imaging

Lee S, Kim Ss, Chang Dr, Kim H, Kim MJ

Background/Aims: This study aimed to compare the diagnostic performances of Liver Imaging Reporting and Data System (LI-RADS) 2018 and Korean Liver Cancer Association-National Cancer Center (KLCA-NCC) 2018 criteria on magnetic...
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Entecavir+tenofovir vs. lamivudine/telbivudine+adefovir in chronic hepatitis B patients with prior suboptimal response

Woo HY, Park JY, Bae SH, Kim CW, Jang JY, Tak WY, Kim DJ, Kim IH, Heo J, Ahn SH

Background/Aims: Suboptimal responses to lamivudine or telbivudine plus adefovir (LAM/LdT+ADV) rescue therapy are common in patients with LAM-resistant hepatitis B virus (HBV) infections. We compared patients switched to entecavir plus...
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