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Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers

Kwon S, Lim HJ

The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it...
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Predictive value of sperm motility characteristics assessed by computer-assisted sperm analysis in intrauterine insemination with superovulation in couples with unexplained infertility

Youn JS, Cha SH, Park CW, Yang KM, Kim JY, Koong MK, Kang IS, Song IO, Han SC

OBJECTIVE: To determine whether characteristics of sperm motility obtained by computer-assisted sperm analysis (CASA) could predict pregnancy after intrauterine insemination (IUI) in couples with unexplained infertility. METHODS: Three hundred eighty-three cycles...
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Genetic association study of a single nucleotide polymorphism of kallikrein-related peptidase 2 with male infertility

Lee SH, Lee S

OBJECTIVE: To investigate a kallikrein-related peptidase 2 (KLK2) single nucleotide polymorphism (SNP) in relation to male infertility because of its role in semen processing. We investigated the genetic association of...
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Does blastomere biopsy in preimplantation genetic diagnosis affect early serum beta-hCG levels?

Cho YJ, Kim JY, Song IO, Lee HS, Lim CK, Koong MK, Kang IS

OBJECTIVE: To determine whether the serum beta-human chorionic gonadotropin (hCG) profile following preimplantation genetic diagnosis (PGD) is lower than that of intracytoplasmic sperm injection (ICSI) cycles. METHODS: A total of 129...
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Comparison of follitropin beta administered by a pen device with follitropin beta administered by a conventional syringe in patients undergoing IVF-ET

Kang HJ, Kim CH, Ahn JW, Lee HA, Kim SH, Chae HD, Kang BM

OBJECTIVE: To compare the effectiveness and convenience of a pen device for the self-administration of follitropin beta with a conventional syringe delivering follitropin beta solution in patients undergoing IVF-ET. METHODS: GnRH...
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Comparison of elective single cleavage-embryo transfer to elective single blastocyst-embryo transfer in human IVF-ET

Kang SM, Lee SW, Jeong HJ, Yoon SH, Lim JH, Lee SG

OBJECTIVE: This study was carried out to compare the clinical outcome of elective single cleavage-embryo transfer (eSCET) to that of elective single blastocyst-embryo transfer (eSBET) in human IVF-ET. METHODS: This study...
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Endometrial histology and predictable clinical factors for endometrial disease in women with polycystic ovary syndrome

Park JC, Lim SY, Jang TK, Bae JG, Kim JI, Rhee JH

OBJECTIVE: This study was aimed to investigate endometrial histology and to find predictable clinical factors for endometrial disease (hyperplasia or cancer) in women with polycystic ovary syndrome (PCOS). METHODS: We investigated...
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Effects of various combinations of cryoprotectants and cooling speed on the survival and further development of mouse oocytes after vitrification

Cha SK, Kim BY, Kim MK, Kim YS, Lee WS, Yoon TK, Lee DR

OBJECTIVE: The objectives of this study were to analyze efficacy of immature and mature mouse oocytes after vitrification and warming by applying various combinations of cryoprotectants (CPAs) and/or super-rapid cooling...
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Integrity of human sperm DNA assessed by the neutral comet assay and its relationship to semen parameters and clinical outcomes for the IVF-ET program

Chi HJ, Chung DY, Choi SY, Kim JH, Kim GY, Lee JS, Lee HS, Kim MH, Roh SI

OBJECTIVE: To explore potential relationships between sperm DNA integrity and both semen parameters and clinical outcomes. METHODS: Semen analysis of 498 samples was performed according to the 2010 criteria of the...
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Expression of peroxiredoxin I regulated by gonadotropins in the rat ovary

Lee YI, Kang WD, Kim MY, Cho MK, Chun SY

OBJECTIVE: Peroxiredoxins (Prxs) play an important role in regulating cellular differentiation and proliferation in several types of mammalian cells. This report examined the expression of Prx isotype I in the...
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