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What should be done for men with sperm DNA fragmentation?

Kim GY

In an age when a small quantity of sperm can lead to pregnancy through in vitro fertilization or intracytoplasmic sperm injection, selecting healthy sperm is important. Sperm DNA fragmentation (SDF)...
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Rapid freezing versus Cryotop vitrification of mouse two-cell embryos

Inna N, Sanmee U, Saeng-anan U, Piromlertamorn W, Vutyavanich T

OBJECTIVE: To compare our in-house method of embryo freezing with Cryotop vitrification in terms of immediate survival, subsequent cleavage and blastocyst formation, and cell numbers in blastocysts. METHODS: Two-cell mouse embryos...
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Thinning and drilling laser-assisted hatching in thawed embryo transfer: A randomized controlled trial

Le MT, Nguyen TT, Nguyen TT, Nguyen VT, Le DD, Nguyen VQ, Cao NT, Aints A, Salumets A

OBJECTIVE: In frozen and thawed embryos, the zona pellucida (ZP) can be damaged due to hardening. Laser-assisted hatching (LAH) of embryos can increase the pregnancy rate. This study compared thinning...
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Early gonadotropin-releasing hormone antagonist protocol in women with polycystic ovary syndrome: A preliminary randomized trial

Shin JJ, Park KE, Choi YM, Kim HO, Choi DH, Lee WS, Cho JH

OBJECTIVE: To prospectively evaluate the efficacy and safety of a fixed early gonadotropin-releasing hormone (GnRH) antagonist protocol compared to a conventional midfollicular GnRH antagonist protocol and a long GnRH agonist...
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Early fragment removal on in vitro fertilization day 2 significantly improves the subsequent development and clinical outcomes of fragmented human embryos

Kim SG, Kim YY, Park JY, Kwak SJ, Yoo CS, Park IH, Sun HG, Kim JW, Lee KH, Park HD, Chi HJ

OBJECTIVE: To determine whether fragment removal on in vitro fertilization (IVF) day 2 improved the subsequent development and pregnancy outcomes of fragmented embryos compared to similar-grade embryos without fragment removal. METHODS:...
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Associations of serum fetuin-A and oxidative stress parameters with polycystic ovary syndrome

Sak S, Uyanikoglu H, Incebiyik , Incebiyik , Hilali NG, Sabuncu T, Sak E

OBJECTIVE: The aim of this study was to compare serum fetuin-A levels and oxidative stress markers, as indicators of insulin resistance, in women with polycystic ovary syndrome (PCOS) and in...
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Angiopoietin-1 and -2 and vascular endothelial growth factor expression in ovarian grafts after cryopreservation using two methods

Cho IA, Lee YJ, Lee HJ, Choi IY, Shin JK, Lee SA, Lee JH, Choi WJ

OBJECTIVE: The favored method of preserving fertility in young female cancer survivors is cryopreservation and autotransplantation of ovarian tissue. Reducing hypoxia until angiogenesis takes place is essential for the survival...
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