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Potential Molecular and Cellular Mechanism of Psychotropic Drugs

Seo MS, Scarr E, Lai CY, Dean B

  • KMID: 2279941
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):94-110.
Psychiatric disorders are among the most debilitating of all medical illnesses. Whilst there are drugs that can be used to treat these disorders, they give sub-optimal recovery in many people...
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Combined Clozapine and Electroconvulsive Therapy in a Japanese Schizophrenia Patient: A Case Report

Yoshino Y, Ozaki Y, Kawasoe K, Ochi S, Niiya T, Sonobe N, Matsumoto , Ueno SI

  • KMID: 2279949
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):160-162.
Clozapine is well-known for successful use in schizophrenic patients treatment resistant to other antipsychotics. However, even with clozapine, 25% of schizophrenic patients are not in remission. Recently, as adjunctive treatment...
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Antidepressant Effects of Ketamine on Depression-like Behavior in Juvenile Mice after Neonatal Dexamethasone Exposure

Li SX, Zhang JC, Wu J, Hashimoto

  • KMID: 2279943
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):124-127.
OBJECTIVE: Pediatric depression is associated with significant functional impairment at school and at work. Recently, we reported on depression-like behavior in juvenile mice neonatally exposed to dexamethasone (DEX) as a...
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Therapeutic Modalities for Treatment Resistant Depression: Focus on Vagal Nerve Stimulation and Ketamine

Shah A, Carreno FR, Frazer A

  • KMID: 2279940
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):83-93.
Treatment resistant depression (TRD) is a global health concern affecting a large proportion of depressed patients who then require novel therapeutic options. One such treatment option that has received some...
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Acamprosate-induced Extrapyramidal Symptoms in an Elderly Patient with Alcohol Dependence

Woo J, Rim HD

  • KMID: 2279951
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):166-168.
Acamprosate reduces the craving for alcohol by decreasing glutamate activity and increasing gamma-aminobutyric acid (GABA) action in patients with alcohol dependence. Acamprosate has tolerable side effects that include diarrhea, headache,...
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Late-onset Quetiapine-related Tardive Dyskinesia Side Effects in a Patient with Psychotic Depression

Hou YC, Lai CH

  • KMID: 2279950
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):163-165.
The atypical antipsychotics were believed to induce less extrapyramidal syndrome, including tardive dyskinesia (TD). Since the introduction of the quetiapine, it is also reported with less TD side effects. It...
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Aripiprazole in the Treatment of Refractory Mood Disorders: A Case Series

Muneer A

  • KMID: 2279948
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):157-159.
Major depressive disorder and bipolar disorders are among the commonest neuropsychiatric conditions, affecting persons of both sexes which belong to all age groups. Comorbidity is the rule rather than the...
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Anti-dementia Activity of Nobiletin, a Citrus Flavonoid: A Review of Animal Studies

Nakajima A, Ohizumi Y, Yamada K

  • KMID: 2279939
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):75-82.
Alzheimer's disease (AD), the most common form of dementia among the elderly, is characterized by the progressive decline of cognitive function and has a detrimental impact worldwide. Despite intensive laboratory...
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Needs of Siblings of Persons with Psychosis: A Systematic Descriptive Review

Amaresha A, Venkatasubramanian G, Muralidhar D

  • KMID: 2279942
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):111-123.
Research on caregivers of psychosis has predominantly focused on parents and spouses. Issues related to siblings of persons with psychosis (SOPP) are yet to be evaluated comprehensively. Like parents and...
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Prescription Patterns for Patients with Schizophrenia in Korea: A Focus on Antipsychotic Polypharmacy

Kim HY, Lee HW, Jung SH, Kang MH, Bae JN, Lee JS, Kim CE

  • KMID: 2279944
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):128-136.
OBJECTIVE: This study investigated the prescription patterns for Korean patients with schizophrenia with a particular focus on antipsychotic polypharmacy. All data were gathered from patients presenting at 41 tertiary university...
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GABA Receptors Genes Polymorphisms and Alcohol Dependence: No Evidence of an Association in an Italian Male Population

Terranova , Tucci M, Di Pietra , Ferrara SD

  • KMID: 2279946
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):142-148.
OBJECTIVE: The genes encoding for gamma-aminobutyric acid (GABA) A and B receptors may be considered as candidates for alcoholism; genetic alterations at this level may produce structural and functional diversity...
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Validation of the Korean Version of the Children's Revised Impact of Event Scale

Oh EA, Park EJ, Lee SH, Bae SM

  • KMID: 2279947
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):149-156.
OBJECTIVE: This study examined the psychometric properties of the Korean version of the Children's Revised Impact of Event Scale (CRIES) and its validity as a screening instrument for the post-traumatic...
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The Amygdala's Neurochemical Ratios after 12 Weeks Administration of 20 mg Long-acting Methylphenidate in Children with Attention Deficit and Hyperactivity Disorder: A Pilot Study Using 1H Magnetic Resonance Spectroscopy

Wiguna T, Guerrero A, Wibisono S, Sastroasmoro S

  • KMID: 2279945
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):137-141.
OBJECTIVE: Recent pediatric studies have suggested a correlation between decreased amygdala volume and attention deficit and hyperactivity disorder (ADHD) symptoms, including the emotional dysregulation. To investigate the hypothesis that medication...
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