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22 results

Naltrexone-associated Visual Hallucinations: A Case Report

Lee DB, Woo YS, Bahk WM

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):329-331.
  • doi: 10.9758/cpn.2019.17.2.329
Naltrexone is a competitive antagonist of μ, δ, and κ opioid receptors. Naltrexone has been investigated for use an as anti-obesity agent in both the general population and in patients...
Musical Hallucination Caused by Ceftazidime in a Woman with a Hearing Impairment

Song CI, Jung YE

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):326-328.
  • doi: 10.9758/cpn.2019.17.2.326
Musical hallucinations remain a poorly understood clinical phenomenon, possibly because these types of hallucination have multiple causes and are rarely the focus of published reports. Here, the case of a...
Comorbid Zolpidem Dependence and Over-the-Counter Compound Analgesic Abuse

Kim H, Shin C, Ko YH, Han C

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):323-325.
  • doi: 10.9758/cpn.2019.17.2.323
Zolpidem is a commonly prescribed hypnotic used to treat insomnia. However, its potential for abuse and dependence has recently become controversial. Although over-the-counter (OTC) medications are widely used, their abuse...
Alexithymia, Suicide Ideation and Homocysteine Levels in Drug Naïve Patients with Major Depression: A Study in the “Real World” Clinical Practice

De Berardis D, Olivieri L, Rapini G, Di Natale , Serroni N, Fornaro M, Orsolini L, Valchera A, Carano A, Vellante F, Varasano P, Pressanti , Serafini G, Pompili M, Martinotti G, Di Giannantonio M

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):318-322.
  • doi: 10.9758/cpn.2019.17.2.318
OBJECTIVE: This study was performed to elucidate relationships between alexithymia, suicide ideation and homocysteine levels in drug-naïve outpatients with major depressive disorder (MDD). METHODS: Sixty seven outpatients with MDD with melancholic...
Adjunctive Lurasidone Suppresses Food Intake and Weight Gain Associated with Olanzapine Administration in Rats

Reynolds G, Dalton CF, Watrimez W, Jackson J, Harte MK

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):314-317.
  • doi: 10.9758/cpn.2019.17.2.314
OBJECTIVE: Lurasidone is an antipsychotic drug that shows a relative lack of weight gain common to many antipsychotics. Aripiprazole and ziprasidone also show little weight gain and can reduce olanzapine-induced...
Effect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blood

Sonmez EO, Uguz F, Sahingoz M, Sonmez G, Kaya N, Camkurt MA, Gokmen Z, Basaran M, Gezginc K, Erdem SS, Dulger HH, Tasyurek E

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):308-313.
  • doi: 10.9758/cpn.2019.17.2.308
OBJECTIVE: We aimed to assess the association between cord blood brain-derived neurotrophic factor (BDNF) concentration and maternal depression during pregnancy. METHODS: A total of 48 pregnant women, admitted for elective caesarean...
Protocol and Rationale: A 24-week Double-blind, Randomized, Placebo Controlled Trial of the Efficacy of Adjunctive Garcinia mangostana Linn. (Mangosteen) Pericarp for Schizophrenia

Turner A, McGrath JJ, Dean OM, Dodd S, Baker A, Cotton SM, Scott JG, Kavanagh B, Ashton MM, Walker AJ, Brown E, Berk M

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):297-307.
  • doi: 10.9758/cpn.2019.17.2.297
OBJECTIVE: Garcinia mangostana Linn., commonly known as mangosteen, is a tropical fruit with a thick pericarp rind containing bioactive compounds that may be beneficial as an adjunctive treatment for schizophrenia....
Medication Adherence Using Electronic Monitoring in Severe Psychiatric Illness: 4 and 24 Weeks after Discharge

Lee Y, Lee MS, Jeong HG, Youn HC, Kim SH

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):288-296.
  • doi: 10.9758/cpn.2019.17.2.288
OBJECTIVE: The purpose of this study was to examine post-hospitalization outpatient drug adherence in patients with severe psychiatric illness, including bipolar disorder and schizophrenia, and to investigate factors associated with...
Physical Health Literacy and Health-related Behaviors in Patients with Psychosis

Kim SW, Park WY, Jhon M, Kim M, Lee JY, Kim SY, Kim JM, Shin IS, Yoon JS

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):279-287.
  • doi: 10.9758/cpn.2019.17.2.279
OBJECTIVE: This study compared the levels of knowledge of physical illnesses and patterns of health behaviors between patients with psychosis and the general population. METHODS: A total of 712 participants were...
Association between Therapeutic Alliance and Adherence in Outpatient Schizophrenia Patients

Chang JG, Roh D, Kim CH

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):273-278.
  • doi: 10.9758/cpn.2019.17.2.273
OBJECTIVE: Although various clinical factors that affect medication adherence in schizophrenia have been studied, the role of the therapeutic alliance has not been studied in detail. Accordingly, we investigated the...
Antidepressant-like Effects Induced by Chronic Blockade of the Purinergic 2X7 Receptor through Inhibition of Non-like Receptor Protein 1 Inflammasome in Chronic Unpredictable Mild Stress Model of Depression in Rats

Aricioglu , Ozkartal C, Bastaskin , Tüzün E, Kandemir C, Sirvanci S, Kucukali C, Utkan T

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):261-272.
  • doi: 10.9758/cpn.2019.17.2.261
OBJECTIVE: Purinergic 2X7 receptor (P2X7R) activation is known to be involved in pathogenesis of depression. Our aims were to investigate P2X7R-activated inflammasome pathways in parallel with induction of depression and...
Effects of Amisulpride Adjunctive Therapy on Working Memory and Brain Metabolism in the Frontal Cortex of Patients with Schizophrenia: A Preliminary Positron Emission Tomography/Computerized Tomography Investigation

Park JH, Hong JS, Kim SM, Min KJ, Chung US, Han DH

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):250-260.
  • doi: 10.9758/cpn.2019.17.2.250
OBJECTIVE: Dopamine plays a significant role in working memory by acting as a key neuromodulator between brain networks. Additionally, treatment of patients with schizophrenia using amisulpride, a pure dopamine class...
Serum Levels of High Sensitivity C-reactive Protein in Drug-naïve First-episode Psychosis and Acute Exacerbation of Schizophrenia

Bolu A, Aydin MS, Akgün A, CoÅŸkun A, Garip B, Öznur T, Çelik C, Uzun Ã

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):244-249.
  • doi: 10.9758/cpn.2019.17.2.244
OBJECTIVE: Findings about inflammatory processes in schizophrenia are increasing day by day. Inflammatory processes in schizophrenia are associated with both its etiology and clinical symptoms. Serum high-sensitivity C-reactive protein (hsCRP)...
Effects of Chronic and Acute Lithium Treatment on the Long-term Potentiation and Spatial Memory in Adult Rats

Yousef M, Kavraal Å, Artış AS, Süer C

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):233-243.
  • doi: 10.9758/cpn.2019.17.2.233
OBJECTIVE: Although, accumulating evidence is delineating a neuroprotective and neurotrophic role for lithium (Li), inconsistent findings have also been reported in human studies especially. Moreover, the effects of Li infusion...
Heart Rate Variability Biofeedback Increased Autonomic Activation and Improved Symptoms of Depression and Insomnia among Patients with Major Depression Disorder

Lin IM, Fan SY, Yen CF, Yeh YC, Tang TC, Huang MF, Liu TL, Wang PW, Lin HC, Tsai HY, Tsai YC

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):222-232.
  • doi: 10.9758/cpn.2019.17.2.222
OBJECTIVE: Autonomic imbalance is considered a psychopathological mechanism underlying major depressive disorder (MDD). Heart rate variability (HRV) is an index for autonomic activation. Poor sleep quality is common among patients...
Evaluation of Endothelial Dysfunction in Bipolar Affective Disorders: Serum Endocan and Urotensin-II Levels

Oral E, Halici Z, Cinar I, Ozcan E, Kutlu Z

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):211-221.
  • doi: 10.9758/cpn.2019.17.2.211
OBJECTIVE: This study investigated changes in urotensin-II (U-II) and endocan levels which can be used as an early biological marker of endothelial injury in the episode and remission phases of...
Predicting Behavior Problems in Korean Preschoolers: Interactions of the SLC6A4 Gene and Maternal Negative Affectivity

Ha J, Jun HJ, Shin H, Chung IJ, Park E, Min SK, Kim E

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):200-210.
  • doi: 10.9758/cpn.2019.17.2.200
OBJECTIVE: This study aimed to investigate whether maternal negative affectivity (MNA) moderates the effect of genetic polymorphism of SLC6A4 on behavior problems in children. METHODS: Study participants comprised 143 preschoolers and...
Abnormalities in Inflammatory Cytokines Confer Susceptible to Chronic Neuropathic Pain-related Anhedonia in a Rat Model of Spared Nerve Injury

Fang X, Zhan G, Zhang J, Xu H, Zhu B, Hu Y, Yang C, Luo A

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):189-199.
  • doi: 10.9758/cpn.2019.17.2.189
OBJECTIVE: Patients with chronic neuropathic pain (CNP) have a higher incidence to develop depression. However, its pathogenesis has not yet been fully elucidated. Here we aimed to investigate the role...
Posttraumatic Embitterment Disorder in Patients with Chronic Kidney Disease

Lee K, Song HC, Choi EJ, Pae CU, Kim YK

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):183-188.
  • doi: 10.9758/cpn.2019.17.2.183
OBJECTIVE: Posttraumatic embitterment disorder (PTED), a subgroup of an adjustment disorder, is a feeling with anger and helplessness. Hemodialysis may be a trigger event leading to PTED. We investigated the...
Schizophrenia and Corollary Discharge: A Neuroscientific Overview and Translational Implications

Parlikar R, Bose A, Venkatasubramanian G

  • Clin Psychopharmacol Neurosci.
  • 2019 Mar;17(2):170-182.
  • doi: 10.9758/cpn.2019.17.2.170
Corollary discharge mechanism refers to the suppression of sensory consequences of self-generated actions; a process that serves to distinguish between self and non-self based on discrimination of origination of action....

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