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Abuse Liability of Baclofen

Praharaj S

No abstract available.
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Combined Use of Duloxetine and Olanzapine in the Treatment of Urologic Chronic Pelvic Pain Syndromes Refractory to Conventional Treatment: A Case Report

Bi B, Shan L, Zhou D

Patients with urologic chronic pelvic pain syndromes (UCPPS) report interstitial cystitis/bladder pain syndrome and/or chronic prostatitis/chronic pelvic pain syndrome. The pathogenesis of these syndromes remains unclear and there is currently...
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Risperidone Related Raynaud's Phenomenon: An Adolescent Case

Güneş S, Ekinci O, Teke H, Yıldırım V

Raynaud's phenomenon is a recurrent vasospastic condition with reducing in peripheral blood flow due to cold, or emotional stress. White, blue and red discolorations occur during the attacks. Serotonin reuptake...
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Polydipsia as a Precursor of Manic Episode in Bipolar Affective Disorder Patients with Alcohol Use Disorder

Ceylan ME, Ãœnsalver , Evrensel A

Bipolar affective disorder (BD) diagnosis and initiation of appropriate treatment are often delayed, and this is associated with poorer outcomes, such as rapid cycling or cognitive decline. Therefore, identifying certain...
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Limbic Encephalitis Manifesting as Selective Amnesia and Seizure-like Activity: A Case Report

Kim SY, Um YH, Lim SC, Jeong JH

Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histopathological evidence of medial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI-1) is an auto-antigen associated with...
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Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder

Ferrari P, Parisi MM, Colombo R, Becker M, Fries G, Ascoli BM, Géa LP, Kauer-Sant’anna M, Kapczinski F, Klamt F, Guma FT, Rosa AR, Barbé-Tuana FM

OBJECTIVE: Evidence has suggested that immune imbalance is involved with bipolar disorder (BD); however, its precise mechanism is poorly understood. This study investigated whether biochemical changes in the serum from...
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The Association between Suicide Attempts and Toxoplasma gondii Infection

Bak J, Shim SH, Kwon YJ, Lee HY, Kim JS, Yoon H, Lee YJ

OBJECTIVE: Chronic ‘latent’ infection by Toxoplasma gondii is common and most of the hosts have minimal symptoms or they are even asymptomatic. However, there are possible mechanisms by which T....
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The Diagnostic Value of Malondialdehyde, Superoxide Dismutase and Catalase Activity in Drug Naïve, First Episode, Non-Smoker Generalized Anxiety Disorder Patients

Fındıklı E, Camkurt MA, İzci F, Karaaslan , Fındıklı HA, Sümer P, Kurutaş E

OBJECTIVE: Generalized anxiety disorder (GAD) is a common anxiety disorder. Although lots of research done to reveal neurobiological basis of GAD, it is still unclear. Diagnosis of GAD depends on...
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Korean Medication Algorithm for Depressive Disorders 2017: Third Revision

Seo JS, Bahk WM, Wang HR, Woo YS, Park YM, Jeong JH, Kim W, Shim SH, Lee JG, Jon DI, Min KJ

OBJECTIVE: In 2002, the Korean Society for Affective Disorders developed the guidelines for the treatment of major depressive disorder (MDD), and revised it in 2006 and 2012. The third revision...
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The Effects of Repetitive Transcranial Magnetic Stimulation at Dorsolateral Prefrontal Cortex in the Treatment of Migraine Comorbid with Depression: A Retrospective Open Study

Kumar S, Singh S, Kumar N, Verma R

OBJECTIVE: The literature on managing migraine non-responsive to pharmacological approaches and that co-occurring with depression is scanty. The comorbid condition predicts a poorer prognosis for migraine as well as depression....
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Efficacy and Safety Profile of Risperidone Long-acting Injection in Adolescents in a Real-life Setting

Ardic UA, Küçükköse M, Inci SB, Ercan ES

OBJECTIVE: Risperidone long-acting injection (RLAI) was shown to be an alternative option in adult patients, but there is not available data in child and adolescents about this medication. The aim...
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Hippocampal Subfields Volume Reduction in High Schoolers with Previous Verbal Abuse Experiences

Lee SW, Yoo JH, Kim KW, Kim D, Park H, Choi J, Teicher MH, Jeong B

OBJECTIVE: Reduced hippocampal volume and alterations in white matter tracts have been frequently reported in adults having the history of emotional maltreatment. We investigated whether these structural change occur in...
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Thiol Disulfide Homeostasis in Schizophrenic Patients Using Atypical Antipsychotic Drugs

Dogan HO, Ersan EE, Aydin H, Erdoğan S, Erşan S, Alişik M, Bakir S, Erel O, Koç D

OBJECTIVE: Schizophrenia is a severe, debilitating mental disorder characterized by behavioral abnormalities. Although several studies have investigated the role of oxidative stress and the effects of antipsychotic drugs on oxidative...
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Genotype-phenotype Analysis of Paraoxonase 1 in Schizophrenic Patients Treated with Atypical Antipsychotics

Pavăl D, Nemeş B, Rusu RL, Dronca E

OBJECTIVE: Recent studies suggest a possible involvement of low paraoxonase 1 (PON1) enzyme activities in the association between schizophrenia, treatment with atypical antipsychotics and increased cardiovascular (CVD) risk. In the...
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From Neurons to Social Beings: Short Review of the Mirror Neuron System Research and Its Socio-Psychological and Psychiatric Implications

Jeon H, Lee SH

The mirror neuron system (MNS) is a brain network activated when we move our body parts and when we observe the actions of other agent. Since the mirror neuron's discovery...
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Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies

Tripathi A, Kar SK, Shukla R

Cognitive deficits are one of the core symptoms of schizophrenia that evolve during the course of schizophrenia, after being originated even before the onset of illness. Existing pharmacological and biological...
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The Present and Future of Precision Medicine in Psychiatry: Focus on Clinical Psychopharmacology of Antidepressants

Serretti A

Precision medicine is a concept which is recently gaining momentum in all branches of medicine. In particular in psychiatry it is greatly needed given the huge societal costs of psychiatric...
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