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Early Intervention for Psychosis with N-Methyl-D-Aspartate Receptor Modulators

Dong C, Hashimoto

No abstract available.
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Primary Prevention of Alzheimer's Disease in Developing Countries

Kavoor AR, Mitra S, Mahintamani T, Chatterjee SS

No abstract available.
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A Case of Nasu-Hakola Disease without Fractures or Consanguinity Diagnosed Using Exome Sequencing and Treated with Sodium Valproate

Yamazaki K, Yoshino Y, Mori Y, Ochi S, Yoshida T, Ishimaru T, Ueno SI

Nasu-Hakola disease (NHD) is a rare autosomal recessive neuropsychiatric disorder characterized by bone cysts, fractures, and cognitive impairment. Two genes are responsible for the development of NHD; TYROBP and TREM2....
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Atomoxetine Augmentation in a Case of Treatment Resistant Panic Disorder with Multiple Augments Failure: A Case Report

Ram D, Patil S, Gowdappa B, Rajalakshmi I

Atomoxetine, a selective norepinephrine inhibitor, is effective in comorbid anxiety and attention deficit hyperactivity disorder, however its role in panic disorder is unknown. We are presenting a case of panic...
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The Accompanying Changes in Brain Structure of a Remitted Depression Patient with the Bupropion Treatment

Hou YC, Lai CH

The impacts from the bupropion on the brain structures have seldom been mentioned in the literature. The bupropion is a kind of antidepressant with dual action in the norepinephrine and...
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Emerging Hyperprolactinemic Galactorrhea in Obsessive Compulsive Disorder with a Stable Dose of Fluoxetine

Chatterjee SS, Mitra S, Mallik N

While fluoxetine (FXT) is a frequently prescribed selective serotonin reuptake inhibitor (SSRI), with few major side-effects; altered serotonergic transmissions in hypothalamic pathways might lead to a distressing, and often embarrassing,...
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Characteristic Risk Factors Associated with Planned versus Impulsive Suicide Attempters

Kim J, Lee KS, Kim DJ, Hong SC, Choi KH, Oh Y, Wang SM, Lee HK, Kweon YS, Lee CT, Lee KU

OBJECTIVE: The present study aimed to investigate predictors for planned suicide attempters. METHODS: This study included 1,003 patients who attempted suicide and visited emergency department. They were divided into two groups,...
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High Prevalence of Psychotropics Overdose among Suicide Attempters in Korea

Kim J, Kim M, Kim YR, Choi KH, Lee KU

OBJECTIVE: The availability of suicide methods affects the risk of suicide attempts. This study examined the patterns of substances ingested by suicide attempters (SAs) and the characteristics of SAs using...
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Relationship between Suicidality and Low Self-esteem in Patients with Schizophrenia

Yoo T, Kim SW, Kim SY, Lee JY, Kang HJ, Bae KY, Kim JM, Shin IS, Yoon JS

OBJECTIVE: Low self-esteem is associated with suicide risk in the general psychiatric population. The aim of this study was to examine associations between suicidality and self-esteem in patients with schizophrenia. METHODS:...
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The Relationship between Language Ability and Cognitive Function in Patients with Schizophrenia

Kim SJ, Shim JC, Kong BG, Kang JW, Moon JJ, Jeon DW, Jung SS, Seo BJ, Jung DU

OBJECTIVE: Cognitive dysfunction is common in people with schizophrenia, and language disability is one of the most notable cognitive deficits. This study assessed the use and comprehension ability of the...
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Brain-derived Neurotrophic Factor Is Associated with Cognitive Impairment in Elderly Korean Individuals

Lee SJ, Baek JH, Kim YH

OBJECTIVE: Brain-derived neurotrophic factor (BDNF) is a neurotrophin that is widely expressed in the mammalian brain and acts to regulate neuronal survival and influence cognitive processes. The present study measured...
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Antipsychotic Prescribing Patterns in First-episode Schizophrenia: A Five-year Comparison

Roh D, Chang JG, Yoon S, Kim CH

OBJECTIVE: Early treatment choice is critical in first-episode schizophrenia-spectrum disorders. The purpose of this study was to describe prescribing trends of antipsychotics use in patients with first-episode schizophrenia in 2005...
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The Changes of Psychometric Profiles after Medical Treatment of Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia

Cho KJ, Lee NS, Lee YS, Jeong WJ, Suh HJ, Kim JC, Koh JS

OBJECTIVE: To investigate the relationship of somatization and depression with the degree of lower urinary tract symptoms suggestive of benign prostate hyperplasia (LUTS/BPH) and changes in psychometric profiles including somatization...
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Risk Factors for Anxiety in Major Depressive Disorder Patients

Xin LM, Chen L, Ji ZP, Zhang SY, Wang J, Liu YH, Chen DF, Yang FD, Wang G, Fang YR, Lu Z, Yang HC, Hu J, Chen ZY, Huang Y, Sun J, Wang XP, Li HC, Zhang JB, Si TM

OBJECTIVE: To analyze the sociodemographic and clinical factors related to anxiety in patients with major depressive disorder (MDD). METHODS: This study involved a secondary analysis of data obtained from the Diagnostic...
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Gender Differences in the Clinical Characteristics of Psychotic Depression: Results from the CRESCEND Study

Park SC, Ostergaard SD, Kim JM, Jun TY, Lee MS, Kim JB, Yim HW, Park YC

OBJECTIVE: To test whether there are gender differences in the clinical characteristics of patients with psychotic depression (PD). METHODS: Using data from the Clinical Research Center for Depression (CRESCEND) study in...
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Association between ABCB1 Polymorphisms and Antidepressant Treatment Response in Taiwanese Major Depressive Patients

Chang HH, Chou CH, Yang YK, Lee IH, Chen PS

OBJECTIVE: The multidrug resistance 1 (ABCB1, MDR1) gene, encoding P-glycoprotein, is extensively distributed and expressed in various tissues, such as a blood-brain barrier transporter. P-glycoprotein plays an important role in...
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Efficacy of Adjunctive High Frequency Repetitive Transcranial Magnetic Stimulation of Right Prefrontal Cortex in Adolescent Mania: A Randomized Sham-Controlled Study

Pathak V, Sinha VK, Praharaj S

OBJECTIVE: To examine the efficacy of adjunctive right prefrontal high-frequency repetitive transcranial magnetic stimulation (rTMS) treatment in adolescent mania patients as compared to sham stimulation. METHODS: Twenty six right handed patients...
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The Gut-Brain Axis: The Missing Link in Depression

Evrensel A, Ceylan ME

The gut microbiota is essential to human health and the immune system and plays a major role in the bidirectional communication between the gut and the brain. Based on evidence,...
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Classic Studies on the Interaction of Cocaine and the Dopamine Transporter

Verma V

The dopamine transporter is responsible for recycling dopamine after release. Inhibitors of the dopamine transporter, such as cocaine, will stop the reuptake of dopamine and allow it to stay extracellularly,...
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