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8 results

Association Study of Fat-mass and Obesity-associated Gene and Body Mass Index in Japanese Patients with Schizophrenia and Healthy Subjects

Watanabe S, Iga JI, Numata S, Nakataki M, Tanahashi , Itakura M, Ohmori T

  • Clin Psychopharmacol Neurosci.
  • 2012 Dec;10(3):185-189.
  • doi: 10.9758/cpn.2012.10.3.185
OBJECTIVE: Fat-mass and obesity-associated (FTO) gene is known to be involved in the pathophysiology of obesity and a single-nucleotide polymorphism (SNP) rs9939609 of FTO gene is repeatedly confirmed to be...
Characteristics of Drug Overdose in Young Suicide Attempters

Kweon YS, Hwang S, Yeon B, Choi KH, Oh Y, Lee HK, Lee CT, Lee KU

  • Clin Psychopharmacol Neurosci.
  • 2012 Dec;10(3):180-184.
  • doi: 10.9758/cpn.2012.10.3.180
OBJECTIVE: Few studies have focused on the characteristic features of drug overdose in children and adolescents who have attempted suicide in Korea. The present study examined the characteristics of drug...
Iptakalim Preferentially Decreases Nicotine-induced Hyperlocomotion in Phencyclidine-sensitized Rats: A Potential Dual Action against Nicotine Addiction and Psychosis

Volf N, Hu G, Li M

  • Clin Psychopharmacol Neurosci.
  • 2012 Dec;10(3):168-179.
  • doi: 10.9758/cpn.2012.10.3.168
OBJECTIVE: Iptakalim is a putative ATP-sensitive potassium (KATP) channel opener. It is also a novel nicotinic acetylcholine receptor (nAChR) blocker and can antagonize nicotine-induced increase in dopamine release in the...
Association of the Brain-derived Neurotrophic Factor Gene and Clinical Features of Bipolar Disorder in Korea

Min HJ, Cho HS, Kim SJ, Seok JH, Lee E, Jon DI

  • Clin Psychopharmacol Neurosci.
  • 2012 Dec;10(3):163-167.
  • doi: 10.9758/cpn.2012.10.3.163
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) plays an important role in cell survival, differentiation, and cell death as well as in neural plasticity. Recent studies have suggested that BDNF is involved...
Effects of Chronic Mild Stress in Female Bax Inhibitor-1-Gene Knockout Mice

Sui ZY, Chae HJ, Huang GB, Zhao T, Shrestha Muna S, Chung YC

  • Clin Psychopharmacol Neurosci.
  • 2012 Dec;10(3):155-162.
  • doi: 10.9758/cpn.2012.10.3.155
OBJECTIVE: The anti-apoptotic protein Bax inhibitor-1 (BI-1) is a regulator of apoptosis linked to endoplasmic reticulum (ER) stress, and BI-1-/- mice exhibit increased sensitivity to tissue damage. The purpose of...
Are You Being Rejected or Excluded? Insights from Neuroimaging Studies Using Different Rejection Paradigms


  • Clin Psychopharmacol Neurosci.
  • 2012 Dec;10(3):144-154.
  • doi: 10.9758/cpn.2012.10.3.144
Rejection sensitivity is the heightened tendency to perceive or anxiously expect disengagement from others during social interaction. There has been a recent wave of neuroimaging studies of rejection. The aim...
Transcriptional Mechanisms of Drug Addiction

Nestler EJ

  • Clin Psychopharmacol Neurosci.
  • 2012 Dec;10(3):136-143.
  • doi: 10.9758/cpn.2012.10.3.136
Regulation of gene expression is considered a plausible mechanism of drug addiction given the stability of behavioral abnormalities that define an addicted state. Numerous transcription factors, proteins that bind to...
Cognitive Remediation in Schizophrenia

Kaneko Y, Keshavan M

  • Clin Psychopharmacol Neurosci.
  • 2012 Dec;10(3):125-135.
  • doi: 10.9758/cpn.2012.10.3.125
Cognitive deficits in schizophrenia are pervasive, severe, and largely independent of the positive and negative symptoms of the illness. These deficits are increasingly considered to be core features of schizophrenia...

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