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Association between Intracellular Infectious Agents and Schizophrenia

Park MH, Kwon YJ, Jeong HY, Lee HY, Hwangbo Y, Yoon HJ, Shim SH

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):117-123.
OBJECTIVE: A number of studies have reported association between Toxoplasma gondii (T. gondii) and Chlamydia infection and the risk of schizophrenia. The aim of the present study was to compare...
Circadian Rhythm Characteristics in Mood Disorders: Comparison among Bipolar I Disorder, Bipolar II Disorder and Recurrent Major Depressive Disorder

Chung JK, Lee KY, Kim SH, Kim EJ, Jeong SH, Jung HY, Choi JE, Ahn YM, Kim YS, Joo EJ

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):110-116.
OBJECTIVE: Morningness/eveningness (M/E) is a stable characteristic of individuals. Circadian rhythms are altered in episodes of mood disorder. Mood disorder patients were more evening-type than normal population. In this study,...
Learning Difficulties and Working Memory Deficits among Primary School Students in Jakarta, Indonesia

Wiguna T, Setyawati WR N, Kaligis F, Belfer ML

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):105-109.
OBJECTIVE: There are multiple possible etiologies for learning difficulties in children. There is growing evidence that many students identified as having learning difficulties have significant working memory deficits. To determine,...
Use of Clozapine for the Treatment of Schizophrenia: Findings of the 2006 Research on the China Psychotropic Prescription Studies

Si TM, Zhang YS, Shu L, Li KQ, Liu XH, Mei QY, Wang GH, Bai PS, Ji LP, Cheng XS, Ma C, Shi JG, Zhang HY, Ma H, Yu X

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):99-104.
OBJECTIVE: Clozapine is one of the most commonly used antipsychotic drugs in China. To date, few studies have investigated the patterns the prescription of clozapine nationwide. The present study examined...
Effects of the Antioxidant Sulforaphane on Hyperlocomotion and Prepulse Inhibition Deficits in Mice after Phencyclidine Administration

Shirai Y, Fujita Y, Hashimoto

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):94-98.
OBJECTIVE: Accumulating evidence suggests that oxidative stress plays a role in the pathophysiology of schizophrenia and that the potent antioxidants may be potential therapeutic drugs for schizophrenia. This study was...
Assessment between Dopamine Receptor D2 (DRD2) Polymorphisms and Schizophrenia in Korean Population

Cho AR, Lee SM, Kang WS, Kim SK, Chung JH

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):88-93.
OBJECTIVE: The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) of dopamine receptor D2 (DRD2) are associated with schizophrenia in Korean population. METHODS: Four SNPs (rs4648317, rs7131056,...
Treatment Response in First-episode Schizophrenia

Schennach , Riedel M, Musil R, Moller HJ

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):78-87.
First episode schizophrenia (FES) patients tend to be more responsive to treatment. An adequate response has been associated with a favourable long-term course in FES patients. Yet, despite the generally...
Pharmacogenetic Aspects of Antipsychotic Drug-induced Weight Gain: A Critical Review

Reynolds G

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):71-77.
Treatment with several antipsychotic drugs can result in weight gain, which may lead to further morbidity such as type 2 diabetes and cardiovascular disease via the development of metabolic syndrome....
A Review of Brain-derived Neurotrophic Factor as a Candidate Biomarker in Schizophrenia

Nurjono M, Lee J, Chong SA

  • Clin Psychopharmacol Neurosci.
  • 2012 Aug;10(2):61-70.
Brain-derived neurotrophic factor (BDNF), a neurotrophin known to be responsible for development, regeneration, survival and maintenance of neurons has been implicated in the pathophysiology of schizophrenia. This review seeks to...

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