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Aripiprazole Improved Obsessive Compulsive Symptoms in Asperger's Disorder

Celik G, Tahiroglu , Firat S, Avci A

  • Clin Psychopharmacol Neurosci.
  • 2011 Dec;9(3):134-136.
There are many comorbid disorders associated with autism spectrum disorders in child and adolescent population. Although obsessive compulsive disorder and autism spectrum disorders (ASD) comorbidity has common in clinical practice,...
Lack of Association between Brain-Derived Neurotrophic Factor Gene Val66Met Polymorphisms and Generalized Social Anxiety Disorder in Korean Population

Park JS, Lim S, Ha J, Lee MS, Oh KS

  • Clin Psychopharmacol Neurosci.
  • 2011 Dec;9(3):129-133.
OBJECTIVE: Several lines of evidence suggest that brain-derived neurotrophic factor (BDNF) plays a role in the pathophysiology of anxiety. We analyzed the association of the BDNF gene polymorphism, G196A (val66met),...
Factors That Influence the Prescription of Antipsychotics for Patients with Schizophrenia in China

Si TM, Shu L, Li KQ, Liu XH, Mei QY, Wang GH, Bai PS, Ji LP, Chen XS, Ma C, Shi JG, Zhang HY, Ma H, Yu X

  • Clin Psychopharmacol Neurosci.
  • 2011 Dec;9(3):122-128.
OBJECTIVE: To investigate the patterns of antipsychotic use in China and to analyze the factors that influence antipsychotic prescriptions. METHODS: A standardized survey was conducted from May 20 to 24 2002...
The Diagnostic Stability of DSM-IV Diagnoses: An Examination of Major Depressive Disorder, Bipolar I Disorder, and Schizophrenia in Korean Patients

Kim W, Woo YS, Chae JH, Bahk WM

  • Clin Psychopharmacol Neurosci.
  • 2011 Dec;9(3):117-121.
OBJECTIVE: We examined the stability of diagnoses defined by the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) (major depressive disorder [MDD], bipolar I disorder [BID], and schizophrenia [SPR])...
Occupancy of alpha7 Nicotinic Acetylcholine Receptors in the Brain by Tropisetron: A Positron Emission Tomography Study Using [11C]CHIBA-1001 in Healthy Human Subjects

Ishikawa M, Sakata M, Toyohara J, Oda K, Ishii K, Wu J, Yoshida T, Iyo M, Ishiwata K, Hashimoto

  • Clin Psychopharmacol Neurosci.
  • 2011 Dec;9(3):111-116.
OBJECTIVE: Agonists of alpha7-nicotinic acetylcholine receptors (nAChRs) have been developed as potential therapeutic drugs for neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. Positron emission tomography (PET) is a noninvasive...
Prepulse Inhibition of Startle Response: Recent Advances in Human Studies of Psychiatric Disease

Takahashi , Hashimoto , Iwase M, Ishii R, Kamio Y, Takeda M

  • Clin Psychopharmacol Neurosci.
  • 2011 Dec;9(3):102-110.
Prepulse inhibition (PPI) is considered to be one of the most promising neurophysiological indexes for translational research in psychiatry. Impairment of PPI has been reported in several psychiatric diseases, particularly...
Proteomics as a Tool for Understanding Schizophrenia

Martins-de-Souza D

  • Clin Psychopharmacol Neurosci.
  • 2011 Dec;9(3):95-101.
Schizophrenia is likely to be a multifactorial disorder, consequence of alterations in gene and protein expression since the neurodevelopment that together to environmental factors will trigger the establishment of the...

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