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Anaphylaxis diagnosis and management in the Emergency Department of a tertiary hospital in the Philippines

De Vera MJ, Tagaro IC

BACKGROUND: In the Emergency Department (ED), diagnosis and management of anaphylaxis are challenging with at least 50% of anaphylaxis episodes misdiagnosed when the diagnostic criteria of current guidelines are not...
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Analysis of the transcripts encoding for antigenic proteins of bovine gammaherpesvirus 4

Romeo F, Spetter MJ, Moran P, Pereyra S, Odeon A, Perez SE, Verna AE

The major glycoproteins of bovine gammaherpesvirus 4 (BoHV-4) are gB, gH, gM, gL, and gp180 with gB, gH, and gp180 being the most glycosylated. These glycoproteins participate in cell binding...
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Steatocystoma multiplex: A case report of a rare entity

Shin NY, Kang JH, Kim JE, Symkhampa , Huh KH, Yi WJ, Heo MS, Lee SS, Choi SC

Steatocystoma multiplex is an uncommon benign skin disease, which typically manifests as numerous intradermal cysts that can be scattered anywhere on the body. Although usually asymptomatic, it can be significantly...
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Connected in cinema: educational effects of filmmaking classes on medical students

Nam SS, Cha JH, Sung K

PURPOSE: The purpose of this study is to explore what the students experienced in short filmmaking class performed to 1st grade premedical students of a medical school, and to trace...
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Follow-up of Metal-on-Metal Hip Replacements at a Large District Hospital and the Implementation of Medicines and Healthcare Products Regulatory Agency Guidelines: A Review of 297 Patients

Hughes L, Chamberlain K, Robinson H, Sloan A, Choudry Q

BACKGROUND: Medicines and Healthcare products Regulatory Agency (MHRA) guidance for patients with metal-on-metal (MoM) hip replacements was provided in 2012 and updated in 2017 to assist in the early detection...
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A Novel RUNX2 Mutation in a Korean Family with Cleidocranial Dysplasia

Lee JW, Song J, Shin TJ, Hyun HK, Kim YJ, Lee SH, Kim J, Kim JW

Cleidocranial dysplasia (CCD) is an autosomal-dominant disease characterized by the delayed closure of cranial sutures, defects in clavicle formation, supernumerary teeth, and delayed tooth eruption. Defects in the Runt-related transcription...
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Changes in Strauss & Corbin's Grounded Theory

Kim JE

PURPOSE: This study aimed to introduce and elucidate changes in Strauss and Corbin's grounded theory and discuss its application to the field of nursing in South Korea. METHODS: The changes in...
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Computer-based clinical coding activity analysis for neurosurgical terms

Lee JH, Lee JH, Ryu W, Choi BK, Han IH, Lee CM

BACKGROUND: It is not possible to measure how much activity is required to understand and code a medical data. We introduce an assessment method in clinical coding, and applied this...
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Pharmacogenetics and Depression: A Critical Perspective

Corponi F, Fabbri C, Serretti A

Depression leads the higher personal and socio-economical burden within psychiatric disorders. Despite the fact that over 40 antidepressants (ADs) are available, suboptimal response still poses a major challenge and is...
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Analysis of vitamin D-binding protein (VDBP) gene polymorphisms in Korean women with and without endometriosis

Cho MC, Kim JH, Jung MH, Cho IA, Jo HC, Shin JK, Lee SA, Choi WJ, Lee JH

OBJECTIVE: Vitamin D-binding protein (VDBP) mediates various biological processes in humans. The goal of this study was to investigate whether VDBP gene polymorphisms could predispose Korean women to endometriosis. METHODS: We...
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Mental Health Interventions Provided by Volunteer Psychiatrists after the Sewol Ferry Disaster: April 16–November 30, 2014

Bae SM, Lee MS, Kim E, Kim J, Lee J, Hwang JW, Chang HY, Lee CS, Park J, Bhang SY

OBJECTIVE: The aim of this study was to examine the experience of volunteer psychiatrists who provided mental health interventions to adolescents and teachers of Danwon High School from April 16,...
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Myeloproliferative Neoplasm in Newly Diagnosed Acute Ischemic Stroke Patients

Chang MH, Lee JE, Lee MY, Kim KH

OBJECTIVE: Myeloproliferative neoplasm (MPN) is considered as one of the risk factors of ischemic stroke. Some MPN patients manifest stroke as their first symptom. Our purpose was to assess diagnostic...
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Effects of Reminiscence Therapy on Depressive Symptoms in Older Adults with Dementia: A Systematic Review and Meta-Analysis

Kim K, Lee J

PURPOSE: The purpose of this study was to evaluate the effects of reminiscence therapy on depressive symptoms in older adults with dementia using a systematic review and meta-analysis. METHODS: Randomized controlled...
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Development of Artificial Intelligence to Support Needle Electromyography Diagnostic Analysis

Nam S, Sohn MK, Kim HA, Kong HJ, Jung IY

OBJECTIVES: This study proposes a method for classifying three types of resting membrane potential signals obtained as images through diagnostic needle electromyography (EMG) using TensorFlow-Slim and Python to implement an...
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Evolutionary relationship analysis of Middle East respiratory syndrome coronavirus 4a and 4b protein coding sequences

Kim JI, Park S, Bae JY, Park MS

The 4a and 4b proteins of the Middle East respiratory syndrome coronavirus (MERS-CoV) have been described for their antagonism on host innate immunity. However, unlike clustering patterns of the complete...
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Potential Implications of Long Noncoding RNAs in Autoimmune Diseases

Hur K, Kim SH, Kim JM

Long noncoding RNAs (lncRNAs) are non-protein coding RNAs of more than 200 nucleotides in length. Despite the term “noncoding”, lncRNAs have been reported to be involved in gene expression. Accumulating...
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Two Compound Heterozygous Were Identified in SLC26A4 Gene in Two Chinese Families With Enlarged Vestibular Aqueduct

Yu Y, Yang Y, Lu J, Jin Y, Yang Y, Hong E, Shi J, Chen F, Han S, Chu P, Guo Y, Ni X

OBJECTIVES: To investigate the genetic causes of hearing loss with enlarged vestibular aqueduct (EVA) in two children from unrelated two Chinese families. METHODS: Sanger sequencing of all coding exons in SLC26A4...
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Protective effect of lycopene against cytokine-induced β-cell apoptosis in INS-1 cells

Kim K, Jang SE, Bae GD, Jun HS, Oh YS

PURPOSE: Lycopene, a carotenoid with anti-oxidant properties, occurs naturally in tomatoes and pink grapefruit. Although the beneficial effects of lycopene on various disorders have been established, little attention has been...
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STADIUM: Species-Specific tRNA Adaptive Index Compendium

Yoon J, Chung YJ, Lee M

Due to the increasing interest in synonymous codons, several codon bias-related terms were introduced. As one measure of them, the tRNA adaptation index (tAI) was invented about a decade ago....
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Identification of Viral Taxon-Specific Genes (VTSG): Application to Caliciviridae

Kang S, Kim YC

Virus taxonomy was initially determined by clinical experiments based on phenotype. However, with the development of sequence analysis methods, genotype-based classification was also applied. With the development of genome sequence...
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