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Psychological aspects in children and parents of children with chronic kidney disease and their families

Aier A, Pais P, Raman V

Pediatric chronic kidney disease (CKD) is a chronic illness that affects the overall quality of life of patients during childhood. This article highlights the psychological and social burden of CKD...
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Ursolic acid improves the indoxyl sulfate-induced impairment of mitochondrial biogenesis in C2C12 cells

Sasaki Y, Kojima-Yuasa A, Tadano H, Mizuno A, Kon A, Norikura T

BACKGROUND/OBJECTIVES: Patients with chronic kidney disease (CKD) have a high concentration of uremic toxins in their blood and often experience muscle atrophy. Indoxyl sulfate (IS) is a uremic toxin produced...
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Recognizing the importance of physical activity on sarcopenia in chronic kidney disease - Reply

Dubey AK, Sahoo J, Vairappan B, Parameswaran S, PS P

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Disease predictability review using common biomarkers appearing in diabetic nephropathy and neurodegeneration of experimental animals

Yi SS

It is recently known that the kidney and brain have a very rich distribution of blood vessels, and the histological structures of micro-vessels are very similar. Therefore, a number of...
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Cervical Fusion-Requiring Mineral and Bone Disorder Disguised as Osteoporosis in a Chronic Kidney Disease Patient on Hemodialysis: A Case Report

Lee JW, Cho S, Kim KM, Park JH

Bony deformities and fragility fractures in end-stage renal disease (ESRD) patients on long-term hemodialysis can be caused by either osteoporosis or chronic kidney disease-mineral and bone disorder (CKD-MBD). Correct identification...
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Global Kidney Health Atlas: a spotlight on the Asia-Pacific sector

Bharati J, Jha V

Chronic kidney disease (CKD) is a unique public health problem in terms of high expenses required for its management and its increasing worldwide incidence. Understanding the existing structure of CKD...
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Prostaglandin E2 receptors as therapeutic targets in renal fibrosis

Mutsaers HA, Nørregaard R

Prostaglandin E2 (PGE2), a lipid mediator produced by the cyclooxygenase enzyme system, is the main prostaglandin in the kidney. PGE2 is involved in various physiological and pathophysiological processes in the...
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Skeletal muscle energetics in patients with moderate to advanced kidney disease

Ertuglu L, Yildiz A, Gamboa J, Ikizler TA

Sarcopenia, defined as decrease in muscle function and mass, is common in patients with moderate to advanced chronic kidney disease (CKD) and is associated with poor clinical outcomes. Muscle mitochondrial...
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Association between blood pressure and the risk of chronic kidney disease in treatment-naïve hypertensive patients

Lee H, Kwon SH, Jeon JS, Noh H, Han DC, Kim H

Background: Although hypertension is a well-known risk factor for chronic kidney disease (CKD), the blood pressure (BP) at which antihypertensive interventions should be initiated remains to be determined. Therefore, we...
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Pericoronary fat attenuation index in computed tomography angiography is associated with mortality in end-stage renal disease

Cho NJ, Nam BD, Park S, Kim H, Noh H, Jeon JS, Han DC, Lee EY, Gil HW, Kwon SH

Background: An increased pericoronary fat attenuation index (FAI) on computed tomography angiography (CTA) is associated with increased all-cause and cardiac mortality in the general population. However, the ability of pericoronary...
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Resolved Cerebral Venous Hypertension after Angioplasty of Central Venous Stenosis in a Hemodialysis Patient: A Case Report

Kang H, Park ST

Stenosis of the central veins is a common complication in hemodialysis patients. However, cerebral venous hypertension and neurological symptoms caused by central vein stenosis are relatively rare. We present a...
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Exploratory evaluation of the role of cardiac troponin on the clinical outcome of patients visiting emergency department with or without chronic kidney disease

Song M, Kang EJ, Kim T, Park JE, Lee GT, Yoon H, Hwang SY, Cha WC, Shin TG, Sim MS, Jo IJ, Choi JH

  • KMID: 2524953
  • J Korean Soc Emerg Med.
  • 2021 Dec;32(6):548-560.
Objective: Elevated levels of cardiac troponin in chronic kidney disease (CKD) patients admitted to the emergency department (ED) is not well understood and is often ignored. This study aimed to...
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Extraskeletal Calcifications in Children with Maintenance Peritoneal Dialysis

Oh E, Min J, Lim SH, Kim JH, Ha IS, Kang HG, Ahn YH

Chronic kidney disease (CKD)-mineral and bone disorder (CKD-MBD) is a common complication of CKD, often accompanied by extra-skeletal calcification in adult patients. As increased vascular calcification is predicted to increase...
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A Case Report of Very Severe Hyperphosphatemia (19.3 mg/dL) in a Uremic Patient Taking Honey and Persimmon Vinegar

Song SH, Goo YJ, Oh TR, Suh SH, Choi HS, Kim CS, Ma SK, Kim SW, Bae EH

We report a case of severe hyperphosphatemia in advanced CKD with poor compliance. A 55-year-old male patient with underlying type 2 diabetes mellitus, hypertension, and chronic kidney disease presented emergently...
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Metabolic Acidosis in Chronic Kidney Disease: Pathogenesis, Clinical Consequences, and Treatment

Kim HJ

The kidneys play an important role in regulating the acid-base balance. Metabolic acidosis is common in chronic kidney disease (CKD) patients and can lead to poor outcomes, such as bone...
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Hypertension Management in Patients with Chronic Kidney Disease in the Post-SPRINT Era

Jung HH

The management of high blood pressure (BP) is crucial for improving outcomes in patients with chronic kidney disease (CKD). The updated Kidney Disease: Improving Global Outcomes 2021 BP guideline proposes...
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Prevalence and determinants of sarcopenia in Indian patients with chronic kidney disease stage 3 & 4

Dubey AK, Sahoo J, Vairappan B, Parameswaran S, PS P

Objectives There is limited literature on the prevalence and determinants of sarcopenia in the Indian predialysis chronic kidney disease (CKD) population. The current study attempts to characterize sarcopenia in CKD stages...
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Metformin use and cardiovascular outcomes in patients with diabetes and chronic kidney disease: a nationwide cohort study

Kim MH, Oh HJ, Kwon SH, Jeon JS, Noh H, Han DC, Kim H, Ryu DR

Background: Metformin has recently been shown not to increase the risk of lactic acidosis in patients with chronic kidney disease (CKD). Thus, the criteria for metformin use in this population...
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Angiotensin receptor-neprilysin inhibitor in patients with heart failure and chronic kidney disease

Cho IJ, Kang SM

Despite significant advances in the management of heart failure with reduced ejection fraction (HFrEF), there remains an enormous health problem with high morbidity and mortality over the last few decades....
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Analysis of bone in adenine-induced chronic kidney disease model rats

Saito H, Miyakoshi N, Kasukawa Y, Nozaka K, Tsuchie H, Sato C, Abe K, Shoji R, Shimada Y

Objectives The purpose of this study is to investigate the stage of chronic kidney disease (CKD) in adenine-induced CKD model rats by serum analyses, and to examine bone mineral density (BMD),...
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