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Concomitant use of corticosteroid and antimicrobials for liver abscesses in patients with chronic granulomatous disease

Shin KS, Lee MS

Chronic granulomatous disease (CGD) is a rare inherited disorder caused by defective nicotinamide adenine dinucleotide phosphate oxidase enzyme and characterized by recurrent bacterial and fungal infections. Although liver abscess is...
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Targeted busulfan and fludarabine-based conditioning for bone marrow transplantation in chronic granulomatous disease

Ju HY, Kang HJ, Hong CR, Lee JW, Kim H, Song SH, Yu KS, Jang IJ, Park JD, Park KD, Shin HY, Kim JG, Ahn HS

Chronic granulomatous disease (CGD) is a primary immunodeficiency disease caused by impaired phagocytic function. Hematopoietic stem cell transplantation (HSCT) is a definitive cure for CGD; however, the use of HSCT...
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Long-term outcome of patients with p22phox-deficient chronic granulomatous disease on Jeju Island, Korea

Kang HS, Hwang G, Shin KS

PURPOSE: This study investigated the long-term clinical outcomes of patients with p22(phox)-deficient chronic granulomatous disease (CGD) on Jeju Island and retrospectively evaluated the effects of interferon-gamma (IFN-gamma) prophylaxis. METHODS: The medical...
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Identification of a Novel Mutation in the CYBB Gene, p.Asp378Gly, in a Patient With X-linked Chronic Granulomatous Disease

Song SM, Park MR, Kim DS, Kim J, Kim YJ, Ki CS, Ahn K

Chronic granulomatous disease (CGD) is a rare immunodeficiency disease, which is characterized by the lack of a functional nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in phagocytes. The disease presents leukocytosis,...
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A Case of Esophageal Obstruction Complicated in a Patient with Chronic Granulomatous Disease: Esophageal obstruction in Chronic Granulomatous Disease

Kim JS, Hwang J, Choi YH, Kim WS, Kim JG

  • KMID: 1705187
  • Korean J Pediatr Infect Dis.
  • 2014 Apr;21(1):53-58.
Chronic granulomatous disease (CGD) is an inherited immunodeficient disease characterized by recurrent infections and granuloma formation. Granulomatous obstruction of esophagus is one of the rare complications of CGD. The use...
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Rapid Determination of Chimerism Status Using Dihydrorhodamine Assay in a Patient with X-linked Chronic Granulomatous Disease Following Hematopoietic Stem Cell Transplantation

Kim HY, Kim HJ, Ki CS, Kim DW, Yoo KH, Kang ES

Chronic granulomatous disease (CGD) is a rare genetic disease, which is caused by defects in the NADPH oxidase complex (gp91phox, p22phox, p40phox, p47phox, and p67phox) of phagocytes. This defect results...
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Chronic Granulomatous Disease on Jeju Island, Korea

Cho M, Shin KS

Chronic granulomatous disease (CGD) is a rare inherited disorder of a defective NADPH oxidase enzyme, resulting in very low or no production of superoxide and subsequent reactive oxygen species. Consequently,...
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A case report of chronic granulomatous disease presenting with aspergillus pneumonia in a 2-month old girl

Lee E, Oh SH, Kwon JW, Kim BJ, Yu J, Park CJ, Hong SJ

Chronic granulomatous disease (CGD) is an uncommon inherited disorder caused by mutations in any of the genes encoding subunits of the superoxide-generating phagocyte NADPH oxidase system, which is essential for...
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TNF-alpha stimulated IL-8 and IL-10 expression in monocytes from patients with chronic granulomatous disease

Shin KS

PURPOSE: Patients with chronic granulomatous disease (CGD) have genetic mutations in a component of the NADPH oxidase enzyme that is necessary for the generation of the superoxide anion. The profound...
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A Case of X-linked Chronic Granulomatous Disease Diagnosed in Identical Twin

Lee SY, Choi EY, Go SH, Rhim JW, Lee SD, Kim JG

  • KMID: 2170220
  • Infect Chemother.
  • 2007 Dec;39(6):332-337.
Chronic granulomatous disease (CGD) is a rare, inherited congenital immunodeficiency disease, characterized by severe and recurrent infections at epithelial surfaces or in more vital organs such as the liver, lung...
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A Clinical Study of Primary Immunodeficiency Disease in a Single Center in Seoul from 1996 to 2004

Lee JH, Sohn WY, Park HY, Hwang SJ, Seo WH, Kim SJ, Ahn SH, Jo EK, Ahn KM, Lee SI

  • KMID: 2314398
  • Pediatr Allergy Respir Dis.
  • 2005 Dec;15(4):368-380.
PURPOSE: Although primary immunodeficiency disorders are relatively rare, early diagnosis provides the opportunity to reduce morbidity and mortality. The aim of this study was to investigate disease distribution, clinical manifestations,...
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Comparison of Ziehl-Neelsen Stain and TB-PCR on Detection of Mycobacterium tuberculosisin Formalin-fixed, Paraffin-embedded Tissues of Chronic Granulomatous Inflammation

Cho MS, Lee SN, Sung SH, Han WS

  • KMID: 1979365
  • Korean J Pathol.
  • 2003 Dec;37(6):379-383.
BACKGROUND: TB-PCR is a faster and more sensitive method to detect mycobacterium than acid-fast bacilli (AFB) stain, which is laborious and time consuming. We compared the sensitivity and specificity of...
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A Case of Allogeneic Stem Cell Transplantation for Chronic Granulomatous Disease

Lee JH, Lee MJ, Choi ES, Hong SJ, Park CJ, Seo JJ

  • KMID: 2278305
  • Korean J Pediatr Hematol Oncol.
  • 2003 Oct;10(2):282-286.
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency in children caused by an abnormal function of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in the phagocytic cells, which results...
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A Case of Acute Poststreptococcal Glomerulonephritis Associated with Chronic Granulomatous Disease

Kim HT, Lee CG, Seo JW, Kim HS

  • KMID: 2098801
  • J Korean Soc Pediatr Nephrol.
  • 2003 Oct;7(2):217-222.
Chronic granulomatous disease(CGD) is a rare inherited disorder of phagocytic cells which results in a susceptibility to infections by catalase-positive bacteria and fungi, as well as granuloma formation. And acute...
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Aspergillosis of the Thoracic Spine in Chronic Granulomatous Disease: A Case Report

Lee JC, Cho WS, Lee DH, Lim CK, Chang BS, Lee CK

  • KMID: 2105772
  • J Korean Orthop Assoc.
  • 2001 Aug;36(4):389-393.
Chronic granulomatous disease is characterized by recurrent life-threatening infections and the formation of granulomatous lesions caused by the failure of phagocytic oxidative microcidal activity that has resulted from a defect...
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A Case of Chronic Granulomatous Disease in which Enterococci were Observed in Culture

Cho KL, Kim JH, Kim EJ, Yoo CW, Kim CS, Nho US, Kim CK

  • KMID: 2207546
  • J Korean Pediatr Soc.
  • 2000 Jun;43(6):846-850.
Chronic granulomatous disease(CGD) is a genetically inherited disorder caused by the failure of phagocytic cells to produce superoxide. It is characterized by frequent and uncontrollable infection which often lead to death in...
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A Month-Old Infant with Chronic Granulomatous Disease Presented as Pulmonary Aspergillosis

Bae SY, Jung JH, Kim KH, Hong YM, Koo HS, Seoh JY, Hong KS, Kang ES, Won YS, Yoo JH

  • KMID: 2335486
  • J Korean Pediatr Soc.
  • 2000 Mar;43(3):444-449.
Chronic granulomatous disease (CGD) is an uncommon inherited disorder in which phagocytic cells fails to produce antimicrobial superoxide (O2-) due to NADPH oxidase deficiency. This disease can be easily screened...
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Clinical Study on Chronic Granulomatous Disease in Korea

Kim JG, Shin KS, Park JS

  • KMID: 1550776
  • Korean J Immunol.
  • 1999 Sep;21(3):271-283.
Chronic granulomatous disease (CGD) is one of congenital immunodeficient disease and a rare X-linked or autosomal recessive disease characterized by recurrent life- threatening infections and granuloma formation. We observed clinical...
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A Case of Chronic Granulomatous Disease Which is Improved by Interferon- Therapy

Kim JC, Park SS, Yun MJ, Keum DH

  • KMID: 2335259
  • J Korean Pediatr Soc.
  • 1997 Jul;40(7):1021-1025.
Chronic granulomatous disease is a group of rare disorders characterized by a disease of oxidative metabolism of phagocytes with deficit of antimicrobial activity. Also, it has clinical features of chronic...
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2 Cases of X-linked Chronic Granulomatous Disease Diagnosed by Flow Cytometry using 2'7'-dichIorofIuorescein diacetate

Lee JJ, Shim JY, Hong SJ, Park CJ, Chi HS

  • KMID: 2051343
  • Pediatr Allergy Respir Dis.
  • 1997 Mar;7(1):92-100.
Chronic granulomatous disease is a group of rare X-1inked or autosomal recessive genetic disorders due to the NADPH oxidase defect, which causes the defect in neutrophil respiratory burst function, the...
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