- Loss of Heterozygosity on Chromosomes 3p,8p,9p and 17p in the Progression of Squamous Cell Carcinoma of the Larynx
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Yoo WJ, Cho SH, Lee YS, Park GS, Kim MS, Kim BK, Park WS, Lee JY, Kang CS
- KMID: 1786810
- J Korean Med Sci.
- 2004 Jun;19(3):345-351.
- doi: 10.3346/jkms.2004.19.3.345
Previous molecular genetic studies of laryngeal squamous cell carcinoma (SCC)have shown certain chromosomal regions with recurring alterations. But studies of sequential molecular alterations and genetic progression model of laryngeal SCC... -
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- Detection of PML/RARA Rearrangement by Reverse Transcriptase-PCR and Sequencing in a Case of Microgranular Acute Promyelocytic Leukemia Lacking t(15;17) on Karyotype and FISH
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Kim KE, Woo KS, Kim SH, Han JY
- KMID: 1077411
- Korean J Lab Med.
- 2009 Oct;29(5):379-383.
- doi: 10.3343/kjlm.2009.29.5.379
We report a case of morphologically microgranular acute promyelocytic leukemia with PML/RARA fusion transcripts demonstrated by reverse transcriptase-PCR and cDNA sequencing, and no PML/RARA fusion detected by karyotype and FISH... -
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- A t(8;9)(p22;p24)/PCM1-JAK2 Translocation in a Patient With Myeloproliferative Neoplasm and Myeloid Sarcoma: First Report in Korea
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Song I, Lee DH, Lee JH, Jang S, Huh JR, Seo EJ
- KMID: 2373505
- Ann Lab Med.
- 2016 Jan;36(1):79-81.
- doi: 10.3343/alm.2016.36.1.79
No abstract available. -
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- A Case of Trisomy 8 Mosaicism in a Patient with Secondary Amnorreha without Abnormal Phenotype
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Kang HS, Son YS, Kim SY, Park CM, Shim SS
- KMID: 1851094
- J Genet Med.
- 2011 Jun;8(1):67-70.
- doi: 10.5734/JGM.2011.8.1.67
Constitutional trisomy 8 mosaicism (CT8M) is a relatively rare aneuploidy in humans with characteristic phenotypes including typical craniofacial feature (such as deformed skull, prominent forehead, low-set and/or dysplastic ears), skeletal... -
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- A Novel KIT INDEL Mutation in Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1
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Lee JH, Park C, Kim SH, Shin MG
- KMID: 2373559
- Ann Lab Med.
- 2016 Jul;36(4):371-374.
- doi: 10.3343/alm.2016.36.4.371
No abstract available. -
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- The general anesthesia experience of deletion 8p syndrome patient: A case report
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Shin WJ, Kim SD, Kim KH
- KMID: 1766776
- Korean J Anesthesiol.
- 2011 Oct;61(4):332-335.
- doi: 10.4097/kjae.2011.61.4.332
A deletion 8p syndrome is a relatively uncommon congenital disease characterized by mental retardation associated with multiple malformation that make anesthetic management a challenge. Anesthetic management of a patient with... -
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- Spectra of Chromosomal Aberrations in 325 Leukemia Patients and Implications for the Development of New Molecular Detection Systems
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Choi HJ, Kim HR, Shin MG, Kook H, Kim HJ, Shin JH, Suh SP, Ryang DW
- KMID: 1094259
- J Korean Med Sci.
- 2011 Jul;26(7):886-892.
- doi: 10.3346/jkms.2011.26.7.886
This study investigated the spectrum of chromosomal abnormalities in 325 leukemia patients and developed optimal profiles of leukemic fusion genes for multiplex RT-PCR. We prospectively analyzed blood and bone marrow... -
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- Aplastic Anemia with Trisomy 8 and Trisomy 9 in Intestinal Behcet's Disease
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Chung JW, Cheon JH, Lee KJ, Kim JS, Jang SJ, Yang WI, Kim TI, Kim WH
- KMID: 1792777
- Korean J Gastroenterol.
- 2010 Apr;55(4):256-260.
- doi: 10.4166/kjg.2010.55.4.256
Behcet's disease is a multisystemic inflammatory disease characterized with recurrent oral ulcer, genital ulcer, and multiple organ involvement. Aplastic anemia is one of the rarest complications of Behcet's disease. There... -
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- A Case of a del(8p)/dup(8q) Recombinant Chromosome
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Kim JY, Im HB, Son SH, Jeong SY, Sung MJ, Seo SS
- KMID: 2144510
- J Korean Soc Neonatol.
- 2009 May;16(1):76-80.
A male baby with intrauterine growth retardation had a short neck, small hands and feet, hypospadia, both grade I hydronephrosis, type II atrial septal defect, and moderate valvular pulmonary stenosis.... -
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- Near-tetraploidy Acute Myeloid Leukemia with RUNX1-RUNX1T1 Rearrangement Due to Cryptic t(8;21)
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Im M, Lee JK, Lee DY, Hong YJ, Hong SI, Kang HJ, Chang YH
- KMID: 1781603
- Korean J Lab Med.
- 2009 Dec;29(6):510-514.
- doi: 10.3343/kjlm.2009.29.6.510
Tetraploidy or near-tetraploidy is a rare cytogenetic abnormality found in AML, and is divided into primary and secondary forms. The secondary tetraploidy or near-tetraploidy found in AML is known to... -
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- De novo interstitial direct duplication 8 (p21.3p23.1) with Pierre Robin sequence
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Lee SM, Park MS, Park KI, Namgung R, Lee C, Lee JS, Lee KA, Choi JR
- KMID: 2281465
- Korean J Pediatr.
- 2009 May;52(5):603-606.
- doi: 10.3345/kjp.2009.52.5.603
The Pierre Robin sequence (PRS) is the nonrandom association of micrognathia, cleft palate, and glossoptosis, leading to respiratory and feeding difficulties that appear neurogenic rather than mechanical in causation. Genetic... -
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- High Frequency of Genetic Alterations in Non-small Cell Lung Cancer Detected by Multi-target Fluorescence In Situ Hybridization
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Kang JU, Koo SH, Kwon KC, Park JW, Shin SY, Kim JM, Jung SS
- KMID: 1785788
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S47-S51.
- doi: 10.3346/jkms.2007.22.S.S47
Detection of genetic alterations could provide a tool as an adjuvant for the diagnosis of non-small cell lung cancer (NSCLC) and to define patients at risk for early relapse. In... -
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- A Case of Behcet's Disease Associated with Myelodysplastic Syndrome
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Min JA, Kim JE, Oh ST, Cho SG, Cho BK, Park HJ
- KMID: 2247754
- Korean J Dermatol.
- 2009 Nov;47(11):1309-1313.
Behcet's disease (BD) is a multisystemic inflammatory disease that affects various organs and it causes mucocutaneous lesions. BD is only rarely associated with leukemia or other hematologic disorders. Many cases... -
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- A Case of Acute Myeloid Leukemia with Masked t(8;21)
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Kim H, Kim M, Lim J, Kim Y, Han K, Kim SY, Kim HJ
- KMID: 2238849
- Korean J Lab Med.
- 2006 Oct;26(5):338-342.
- doi: 10.3343/kjlm.2006.26.5.338
We report a case that revealed the characteristics of acute myeloblastic leukemia with maturation (AML-M2) on the morphology of the bone marrow biopsy and 45,X,-Y in conventional cytogenetic study, but... -
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- MYC Rearrangement Involving a Novel Non-immunoglobulin Chromosomal Locus in Precursor B-cell Acute Lymphoblastic Leukemia
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Seo JY, Lee SH, Kim HJ, Yoo KH, Koo HH, Cho YG, Choi SI, Kim SH
- KMID: 1380089
- Ann Lab Med.
- 2012 Jul;32(4):289-293.
- doi: 10.3343/alm.2012.32.4.289
MYC rearrangement, a characteristic cytogenetic abnormality of Burkitt lymphoma and several subsets of other mature B-cell neoplasms, typically involves an immunoglobulin gene partner. Herein, we describe a case of precursor... -
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- Prognostic Effect of cytoplasmic CD79a Expression in Acute Myeloid Leukemia with t(8;21)
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Chung HJ, Chi HS, Cho YU, Lee EH, Jang S, Park CJ, Seo EJ
- KMID: 1781541
- Korean J Lab Med.
- 2007 Dec;27(6):388-393.
- doi: 10.3343/kjlm.2007.27.6.388
BACKGROUND: Although cytoplasmic CD79a (cytCD79a) is a highly lineage-specific marker of B lymphoid cells and plays an important role in the diagnosis of acute leukemia, its clinical significance is... -
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- A Case of Systemic Mastocytosis Associated with Acute Myeloid Leukemia Terminating as Aleukemic Mast Cell Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation
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Bae MH, Kim HK, Park CJ, Seo EJ, Park SH, Cho YU, Jang S, Chi HS, Lee KH
- KMID: 1781312
- Ann Lab Med.
- 2013 Mar;33(2):125-129.
- doi: 10.3343/alm.2013.33.2.125
In up to 40% of systemic mastocytosis (SM) cases, an associated clonal hematological non-mast cell lineage disease such as AML is diagnosed before, simultaneously with, or after the diagnosis of... -
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- AML1/ETO Fusion Gene Expression and Clinical Characteristics of Adult Acute Myelogenous Leukemia
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Lee SB, Kim YI, Yoon HJ, Kim SY, Cho KS
- KMID: 1849136
- Korean J Hematol.
- 1998 Oct;33(3):311-321.
BACKGROUND: The (8;21) translocation is one of the most frequent karyotypic abnormalities detected in acute myelogenous leukemia (AML). Up to 92% of cases with this translocation are classified as FAB... -
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- Prenatal Diagnosis of a Satellited Chromosome 8p Results from a de novo Cryptic Translocation between Chromosomes 8 and 22
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Oh AR, Lee BY, Choi EY, Ryu HM, Lee SJ, Jung JY, Park SY
- KMID: 2184491
- J Genet Med.
- 2011 Dec;8(2):135-138.
The authors of the present study report the prenatal detection of a chromosomal abnormality with additional satellites on the distal short arm of chromosome 8. A 35-year-old woman was referred... -
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- A Case of Acute Monoblastic Leukemia with Hexasomy 8
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Cho HS, Kim EH, Lee CH, Kim KD, Hyun MS
- KMID: 1641960
- Korean J Hematol.
- 2002 Aug;37(3):223-226.
Additional copies of chromosome 8 are nonrandom karyotypic aberrations in myeloid malignancies with trisomy 8 being the most common. Hexasomy 8 is extremely rare and only two cases have been... -
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