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Effects of Dextran Sulfate Sodium-Induced Ulcerative Colitis on the Disposition of Tofacitinib in Rats

Bae SH, Kim HS, Choi HG, Chang SY, Kim SH

Tofacitinib, a Janus kinase 1 and 3 inhibitor, is mainly metabolized by CYP3A1/2 and CYP2C11 in the liver. The drug has been approved for the chronic treatment of severe ulcerative...
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Foreign Body Complications in Ears due to Mishandled Hearing Aid Fitting and Proposed Clinical Guidelines to Address the Complications

Cho EH, Cho EH, Shim L, Shim L, Choi HG, Choi HG, Hong SK, Hong SK, Kim HJ, Kim HJ, Lee HJ, Lee HJ

Background: South Korea has one of the world’s fastest aging populations and is witnessing increased age-related hearing impairment cases as well as an increase in the number of hearing aid...
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Achilles Tendon Allograft for Superior Capsule Reconstruction in Irreparable Massive Rotator Cuff Tears

Lee KW, Choi HG, Yang DS, Yu YT, Kim WS, Choy WS

Background: Treatment remains a challenge in massive and irreparable rotator cuff tears (RCTs), and superior capsular reconstruction (SCR) has become an increasingly popular choice. The objective of this study was...
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Hearing Impairment Increases Economic Inequality

Kim SY, Min C, Yoo DM, Chang J, Lee HJ, Park B, Choi HG

Objectives. We evaluated changes in income levels in a hearing-impaired population. Methods. The study subjects were selected from the Korean National Health Insurance Service-Health Screening Cohort data from 2002 to 2015...
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The Effect of a Dietary Companion on Metabolic Syndrome in Adult Women

Choi HG, Kim HJ, Kang SJ

Purpose: This study aimed to compare the differences in the prevalence of metabolic syndrome between menopausal women and women of childbearing age and to determine the risk of metabolic syndrome...
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Effect of Opioids on All-cause Mortality and Opioid Addiction in Total Hip Arthroplasty: a Korea Nationwide Cohort Study

Cha Y, Jang SY, Yoo JI, Choi HG, Hwang JW, Choy W

Background: The purpose of this study was to investigate the use of opioids before and after total hip arthroplasty (THA), to find out the effect of opioid use on mortality...
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KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice

Dorotea D, Lee S, Lee SJ, Lee G, Son JB, Choi HG, Ahn SM, Ha H

Src family kinases (SFKs), an important group of non-receptor tyrosine kinases, are suggested to be excessively activated during various types of tissue fibrosis. The present study investigated the effect of...
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Recombinant Rv0753c Protein of Mycobacterium tuberculosis Induces Apoptosis Through Reactive Oxygen Species-JNK Pathway in Macrophages

Lee KI, Choi S, Choi HG, Kebede SG, Dang TB, Back YW, Park HS, Kim HJ

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains one of the most important infectious diseases worldwide. Mtb and its culture filtrates or sonic extracts induce apoptosis in macrophages. However, there...
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Erratum: In-Depth, Proteomic Analysis of Nasal Secretions from Patients With Chronic Rhinosinusitis and Nasal Polyps

Kim YS, Han D, Kim J, Kim DW, Kim YM, Mo JH, Choi HG, Park JW, Shin HW

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The Role of PI3K/AKT Pathway and NADPH Oxidase 4 in Host ROS Manipulation by Toxoplasma gondii

Choi HG, Gao FF, Zhou W, Sun PR, Yuk JM, Lee YH, Cha GH

Dendritic cell is one of the first innate immune cell to encounter T. gondii after the parasite crosses the host intestinal epithelium. T. gondii requires intact DC as a carrier...
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A Case of Blue Nevus of Posterior Wall of Pharynx

Lee JY, Kim SW, Choi HG, Park BJ

Menalocytic nevi are benign localized pigmented lesions, which usually occur on the cutaneous surface of the body but rarely on the mucous membranes. It is comparatively easy to encounter pigmented...
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Tobacco Smoking and Alcohol Consumption Are Related to Benign Parotid Tumor: A Nested Case-Control Study Using a National Health Screening Cohort

Kim SY, Min C, Oh DJ, Choi HG

OBJECTIVES: To evaluate the relationship among smoking, alcohol consumption, and obesity and benign or malignant parotid tumors in a Korean population. METHODS: The Korean National Health Insurance Service-Health Screening Cohort (for...
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In-Depth, Proteomic Analysis of Nasal Secretions from Patients With Chronic Rhinosinusitis and Nasal Polyps

Kim YS, Han D, Kim J, Kim DW, Kim YM, Mo JH, Choi HG, Park JW, Shin HW

PURPOSE: Chronic rhinosinusitis (CRS) is a complex immunological condition, and novel experimental modalities are required to explore various clinical and pathophysiological endotypes; mere evaluation of nasal polyp (NP) status is...
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Myxoma arising from the parotid gland

Kim SM, Kim CK, Kim SH, Lee MC, Kim JN, Choi HG, Shin DH, Jo DI

Myxomas can be divided into two groups: those derived from the facial skeleton, and those derived from external skeletal soft tissue. Soft tissue myxomas of the head and neck are...
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Experiences of Ego Integrity Recovery in Elderly Cancer Patients: Grounded Theory Approach

Choi HG, Yeom HA

PURPOSE: This study was conducted to derive a substantive theory on lived experiences of elderly cancer patients. METHODS: The data were collected from February to March 2018 through in-depth personal interviews...
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Dipenyleneiodonium Induces Growth Inhibition of Toxoplasma gondii through ROS Induction in ARPE-19 Cells

Sun PR, Gao FF, Choi HG, Zhou W, Yuk JM, Kwon J, Lee YH, Cha GH

Based on the reactive oxygen species (ROS) regulatory properties of diphenyleneiodonium (DPI), we investigated the effects of DPI on host-infected T. gondii proliferation and determined specific concentration that inhibit the...
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A Clinical Study of Acute Epiglottitis: Retrospective Review of 315 Patients in Korea

Kim BJ, Choi BG, Choi HG, Lee JY, Park BJ

BACKGROUND AND OBJECTIVES: Acute epiglottitis is a life-threatening condition that can result in airway obstruction. The present study reports clinical features, management and patient outcomes in an acute epiglottitis. SUBJECTS AND...
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A useful additional medial subbrow approach for the treatment of medial orbital wall fracture with subciliary technique

Kim SM, Kim CK, Jo DI, Lee MC, Kim JN, Choi HG, Shin DH, Kim SH

BACKGROUND: To date, a variety of surgical approaches have been used to reconstruct the medial orbital wall fracture. Still however, there is still a controversy as to their applicability because...
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Relationships between Exercise Behavior and Anger Control of Hospital Nurses

Kim YR, Choi HG, Yeom HA

PURPOSE: This study examined the relationships between nurses' exercise behavior and their anger control using a cross-sectional descriptive design. METHODS: The participants were 290 nurses in South Korea, who completed a...
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Empirical antibiotics for recurrent urinary tract infections in children

Choi HG, Lee JY, Oh CE

OBJECTIVES: The purpose of this study was to compare antibiotic resistance patterns between first urinary tract infection (UTI) and recurrent UTI groups and to obtain information regarding empirical antibiotic selection...
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