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Comparing the Expression of Canonical and Non-Canonical Inflammasomes Across Glioma Grades: Evaluating Their Potential as an Aggressiveness Marker

Kim YJ, Choi W, Sim J, Ahn JW, Park J, Kim D, Jeong JY, Lee JM, Cho K, Moon JS, Moon JH, Sung KS, Lim J

Background Inflammasomes are key in the initiation of inflammatory responses and serve to de-fend the organism. However, when the immune system is imbalanced, these complexes contribute to tumor progression. The...
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Induction of liver transplant immune tolerance in an outbred rat strain model using tacrolimus

Park M, Na H, Joo Y, Cho K, Kim S, Choi J, Baek J, Choi J, You Y, Cho M

Background Orthotopic liver transplantation is the only option for patients with end-stage liver disease and hepatocellular carcinoma. Post-transplant immunosuppressive therapy is important to prevent graft failure. We investigated the effectiveness of...
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A randomized, open-label, single-dose, two-way crossover study to assess the pharmacokinetics between two tablets of fixed-dose combination formulation with raloxifene and cholecalciferol and concomitant administration of each agents in healthy male volunteers

Lee HW, Kang WY, Gwon MR, Choi EJ, Kim EH, Cho K, Lee B, Seong SJ, Yoon YR

A new fixed-dose combination (FDC) formulation of raloxifene 60 mg and cholecalciferol 800 IU was developed to improve the medication compliance and overall efficacy of raloxifene treatment in postmenopausal osteoporosis...
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A Case Report of Isoniazid Induced Encephalopathy

Cho K, Hwang K

A 61-year-old male without a prior neurologic history presented with disturbances in consciousness and seizure that were suspected as related to the treatment of tuberculosis with isoniazid. The neurologic symptoms...
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Verification of the performance of the Bispectral Index as a hypnotic depth indicator during dexmedetomidine sedation

Ki S, Lee D, Lee W, Cho K, Han Y, Lee J

Background: Differences in the effects of propofol and dexmedetomidine sedation on electroencephalogram patterns have been reported previously. However, the reliability of the Bispectral Index (BIS) value for assessing the sedation...
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An Open Medical Platform to Share Source Code and Various Pre-Trained Weights for Models to Use in Deep Learning Research

Kim S, Cho S, Cho K, Seo J, Nam Y, Park J, Kim K, Kim D, Hwang J, Yun J, Jang M, Lee H, Kim N

Deep learning-based applications have great potential to enhance the quality of medical services. The power of deep learning depends on open databases and innovation. Radiologists can act as important mediators...
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Robot-Assisted Stereoelectroencephalography for Pediatric Epilepsy Surgery: The First Case in Korea

Cho K, Chang WS, Kim HD, Chang JW, Kim SH, Lee JS, Kang HC

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Global Trends of Regional Health Information Systems and Suggested Strategic Utilization of their Medical Information

Park H, Kang SH, Lee YS, Lee IS, Hwangbo Y, Cho K

Objectives: Along with the exponentially-growing data produced and accumulated every day through mobile platforms, social networking services, the Internet, and other media, information is becoming increasingly important as a strategic...
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Protective Effects of Silibinin on Helicobacter pyloriinduced Gastritis: NF-κB and STAT3 as Potential Targets

Cho K, Lee HG, Piao JY, Kim SJ, Na HK, Surh YJ

More than half of the world’s populations are considered to be infected by Helicobacter pylori. It causes a chronic inflammation of the stomach, which is implicated in the pathogenesis of...
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Toll-like Receptor 2 in Autoimmune Inflammation

Marks KE, Cho K, Stickling C, Reynolds JM

TLR signaling is critical for broad scale immune recognition of pathogens and/or danger molecules. TLRs are particularly important for the activation and the maturation of cells comprising the innate immune...
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Risk factor leading to complicated appendicitis: pelvic position of the appendix

Koh H, Yang H, Cho K, Jung YY, Chang YS, Kim DH, Kim MS

  • KMID: 2515963
  • J Korean Soc Emerg Med.
  • 2021 Apr;32(2):134-142.
Objective: Several factors contribute to the progression of complicated appendicitis (CA) in patients diagnosed with acute appendicitis. The goal of this study was to investigate whether the pelvic location of...
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[Correction] Relationship between Sleep Duration and Abdominal Obesity in Korean Adult Male: Analysis of Data from the Korean National Health and Nutrition Examination Survey 2016–2017

Lee K, Choi J, Cho K

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Clinical Outcomes of Atypical Inflammatory Variants of Abdominal Aortic Aneurysm

Cho J, Bang JH, Jeong SS, Yi J, Yoon SS, Cho K

Background: Most abdominal aortic aneurysms are degenerative atherosclerotic aneurysms. Inflammatory or infected abdominal aortic aneurysms, which show a slightly different clinical course, are rarely encountered in clinical settings. Therefore, we...
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Macrolide-refractory Mycoplasma pneumoniae pneumonia and hemophagocytic lymphohistiocytosis: case report and literature review

Ma SY, Kim D, Lee J, Cho K, Suh JS, Lee SY

Mycoplasma pneumoniae causes various extra-pulmonary complications. As a rare but fatal hematological complication, hemophagocytic lymphohistiocytosis (HLH) can be observed in children with M. pneumoniae infection. We report a case of...
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Effect of dexamethasone gargle, intravenous dexamethasone, and their combination on postoperative sore throat: a randomized controlled trial

Ki S, Myoung I, Cheong S, Lim S, Cho K, Kim Mh, Han Y, Oh M, Park Y, Kim K, Lee J

Background: Postoperative sore throat (POST) is a complication that decreases patient satisfaction and increases postoperative complaints. The present study was conducted to investigate effects of gargling with dexamethasone, intravenous dexamethasone...
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Relationship between Sleep Duration and Abdominal Obesity in Korean Adult Male: Analysis of Data from the Korean National Health and Nutrition Examination Survey 2016–2017

Lee K, Choi J, Cho K

Background: Sleep is an important physiological process that is required to perform daily functions. Sleep duration is reported to be correlated withobesity. This study investigated the association between sleep duration...
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Pharmacokinetics and bioequivalence of fixed-dose combination of candesartan cilexetil/amlodipine besylate (16/10 mg) versus coadministration of individual formulations in healthy subjects

Lee HW, Kang WY, Jung W, Gwon MR, Yang DH, Kim EH, Cho K, Yoon YR, Seong SJ

This study compared the pharmacokinetics of a fixed-dose combination (FDC) of candesartan (16 mg) and amlodipine (10 mg) versus coadministration of individual formulations to clarify the bioequivalence of the FDC....
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A case of 45,X/47,XXX mosaic Turner syndrome: Clinical manifestations and effect of growth hormone treatment

Yoo SH, Ahn MB, Kim SH, Cho WK, Jung MH, Suh BK, Cho K

In Turner syndrome (TS), 45,X/47,XXX mosaicism is a rare genotype. Due to its low frequency, the clinical features and prognosis are not clearly known. A 10-year-old girl was diagnosed with...
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Vocal cord paralysis following general anesthesia with endotracheal intubation: a clinical review on 43 cases

Lim S, Kim Dc, Cho K, Kim Mh, Moon S, Cho H, Ki S

Background: Vocal cord paralysis (VCP) is one of the most stressful experiences for patients undergoing general anesthesia. Moreover, it is a risk factor for aspiration pneumonia and may increase...
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The question of preoperative anxiety and depression in older patients and family protectors

Lim S, Oh Y, Cho K, Kim Mh, Moon S, Ki S

Background: Higher levels of anxiety increase the risks of surgery, including morbidity and mortality. The objectives of this study were to measure anxiety and depression during the preoperative period and...
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