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Real-world Data-based Adverse Drug Reactions Analysis of Pomalidomide in Patients with Relapsed or Refractory Multiple Myeloma

Ko M, Choi J, Kim S, Kim SH, Cho EJ, Cho YS, Koh YI, Oh JM

Objective: Pomalidomide is a latest-approved immunomodulatory drug used with dexamethasone for patients with relapsed or refractory multiple myeloma (RRMM). However, the real-world safety evidence remains unclear. Thus, we evaluated the...
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Elevated On-Treatment Diastolic Blood Pressure and Cardiovascular Outcomes in the Presence of Achieved Systolic Blood Pressure Targets

Kim DH, Cho IJ, Kim W, Lee CJ, Kim HC, Shin JH, Kang SH, Jung MH, Kwon CH, Lee JH, Kim HL, Kim HM, Cho I, Kang DR, Lee HY, Chung WJ, Kim KI, Cho EJ, Sohn IS, Park S, Shin J, Ryu SK, Kang SM, Pyun WB, Cho MC, Kim JH, Lee JH, Ihm SH, Sung KC

Background and Objectives: This study aimed to investigate the association between cardiovascular events and 2 different levels of elevated on-treatment diastolic blood pressures (DBP) in the presence of achieved systolic...
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Protective effects of Populus tomentiglandulosa against cognitive impairment by regulating oxidative stress in an amyloid beta25–35 -induced Alzheimer's disease mouse model

Kwon YR, Kim JH, Lee S, Kim HY, Cho EJ

BACKGROUND/OBJECTIVES: Alzheimer's disease (AD) is one of the most representative neurodegenerative disease mainly caused by the excessive production of amyloid beta (Aβ). Several studies on the antioxidant activity and protective effects...
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No-Touch vs. Conventional Radiofrequency Ablation Using Twin Internally Cooled Wet Electrodes for Small Hepatocellular Carcinomas: A Randomized Prospective Comparative Study

Suh YS, Choi JW, Yoon JH, Lee DH, Kim YJ, Lee JH, Yu SJ, Cho EJ, Yoon JH, Lee JM

Objective: This study aimed to compare the efficacy between no-touch (NT) radiofrequency ablation (RFA) and conventional RFA using twin internally cooled wet (TICW) electrodes in the bipolar mode for the...
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Prevalence and characteristics of isolated nocturnal hypertension in the general population

Rhee MY, Kim JS, Kim CH, Kim JH, Lee JH, Kim SW, Nah DY, Gu N, Cho EJ, Sung KC, Hong KS

Background/Aims: Ascertaining the prevalence of isolated nocturnal hypertension (INHT) in the general population and identifying the characteristics of patients with INHT may be important to determine patients who should receive...
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Recent Trends in Creatinine Assays in Korea: LongTerm Accuracy-Based Proficiency Testing Survey Data by the Korean Association of External Quality Assessment Service (2011–2019)

Jeong TD, Cho EJ, Lee K, Lee W, Yun YM, Chun S, Song J, Min WK

Background: Accurate serum creatinine (Cr) concentration measurement is essential for evaluating kidney function. In 2011, the Korean Association of External Quality Assessment Service (KEQAS) launched an accuracy-based Cr proficiency testing...
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The relationship between miRNA-26b and connective tissue growth factor in rat models of aortic banding and debanding

Cho JS, Lee J, Park KC, Yang KJ, Cho EJ

Background/Aims: Connective tissue growth factor (CTGF) is a profibrotic factor implicated in pressure overload-mediated myocardial fibrosis. In this study, we determined the role of predicted CTGF-targeting microRNAs (miRNAs) in rat...
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Effects of the fermented Zizyphus jujuba in the amyloid β25-35 -induced Alzheimer's disease mouse model

Kim MJ, Jung JE, Lee S, Cho EJ, Kim HY

BACKGROUD/OBJECTIVES: Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Due to the increased incidence of dementia, there is a corresponding increase concerning the importance of...
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Factors Influencing Compassion Fatigue among Hospice and Palliative Care Unit Nurses

Cho EJ, Cho HH

Purpose: This descriptive study aimed to explore nursing workplace spirituality, end-oflife care stress, and resilience as factors influencing compassion fatigue among nurses working in hospice and palliative care units. Methods:...
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Relationship Between Rotavirus P[6] Infection in Korean Neonates and Histo-Blood Group Antigen: a Single-Center Study

Lee SK, Oh SJ, Choi S, Choi SH, Shin SH, Lee EJ, Cho EJ, Hyun J, Kim HS

Background: Rotaviruses are a major cause of pediatric gastroenteritis. The rotavirus P[6] genotype is the most prevalent genotype isolated from Korean neonates but has rarely been reported in other countries....
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Radiofrequency Ablation Using a Separable Clustered Electrode for the Treatment of Hepatocellular Carcinomas: A Randomized Controlled Trial of a DualSwitching Monopolar Mode Versus a Single-Switching Monopolar Mode

Choi JW, Lee JM, Lee DH, Yoon JH, Kim YJ, Lee JH, Yu SJ, Cho EJ

Objective: This study aimed to prospectively compare the efficacy, safety, and mid-term outcomes of dual-switching monopolar (DSM) radiofrequency ablation (RFA) to those of conventional single-switching monopolar (SSM) RFA in the...
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Smartphone / smartwatch-based cuffless blood pressure measurement : a position paper from the Korean Society of Hypertension

Lee HY, Lee DJ, Seo J, Ihm SH, Kim Ki, Cho EJ, Kim HC, Shin J, Park S, Sohn IS, Chung WJ, Ryu SK, Sung KC, Kim J, Kim DH, Pyun WB, obotKSoH

Smartphone technology has spread rapidly around the globe. According to a report released by the Korea Information Society Development Institute, about 95% of Koreans aged more than 30 years old...
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Report of the Korean Association of External Quality Assessment Service on Hepatitis Serology (2018–2019)

Cho EJ, Choi AR, Ryu JH, Yun SJ, Oh EJ

As a diagnostic immunology program of the Korean Association of External Quality Assessment Service, two trials were organized to assess the external quality of hepatitis serology in 2018 and 2019....
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Paeoniflorin ameliorates Aβ-stimulated neuroinflammation via regulation of NF-κB signaling pathway and Aβ degradation in C6 glial cells

Cho EJ, Kim HY, Lee AY

BACKGROUND/OBJECTIVES: Alzheimer's disease is common age-related neurodegenerative condition characterized by amyloid beta (Aβ) accumulation that leads cognitive impairment. In the present study, we investigated the protective effect of paeoniflorin (PF) against...
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Two-Dimensional-Shear Wave Elastography with a Propagation Map: Prospective Evaluation of Liver Fibrosis Using Histopathology as the Reference Standard

Lee DH, Lee ES, Lee JY, Bae JS, Kim H, Lee KB, Yu SJ, Cho EJ, Lee JH, Cho YY, Han JK, Choi BI

Objective: The aim of this study was to prospectively evaluate whether liver stiffness (LS) assessments, obtained by twodimensional (2D)-shear wave elastography (SWE) with a propagation map, can evaluate liver fibrosis...
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Child-Pugh B or C Cirrhosis Increases the Risk for Bleeding Following Colonoscopic Polypectomy

Soh H, Chun Jy, Hong SW, Park Sn, Lee YB, Lee HJ, Cho EJ, Lee JH, Yu SJ, Im JP, Kim YJ, Kim JS, Yoon JH

Background/Aims: The risk for colonoscopic postpolypec-tomy bleeding (PPB) in patients with chronic liver disease (CLD) remains unclear. We determined the incidence and risk factors for colonoscopic PPB in patients with...
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Inhibition of PI3K/Akt signaling suppresses epithelial-to-mesenchymal transition in hepatocellular carcinoma through the Snail/GSK-3/beta-catenin pathway

Lee S, Choi EJ, Cho EJ, Lee YB, Lee JH, Yu SJ, Yoon JH, Kim YJ

Background/Aims: Patients with advanced hepatocellular carcinoma (HCC) have a poor prognosis due to the lack of effective systemic therapies. Epithelial-to-mesenchymal transition (EMT) is a pivotal event in tumor progression, during...
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Suffering Experience of Primary Caregivers of People with Mental Disabilities in Community Dwellings

Choi EJ, Cho HM, Cho EJ, Lee M

Purpose: The purpose of this study was to examine the suffering experienced by the primary caregiver of people with mental disabilities in community dwellings to explain the fundamental structure thereof. Methods:...
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Clinical Application of Measurement of Left Atrial Function by Speckle-tracking Echocardiography

Cho EJ

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Effectiveness of nivolumab versus regorafenib in hepatocellular carcinoma patients who failed sorafenib treatment

Lee CH, Lee YB, Kim MA, Jang H, Oh H, Kim SW, Cho EJ, Lee KH, Lee JH, Yu SJ, Yoon JH, Kim TY, Kim YJ

Background/Aims: Several treatment options are currently available for patients with hepatocellular carcinoma (HCC) failing previous sorafenib treatment. We aimed to compare the effectiveness of regorafenib and nivolumab in these patients. Methods:...
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