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Dexamethasone Downregulates Expressions of 14-3-3β and γ-Isoforms in Mice with Eosinophilic Meningitis Caused by Angiostrongylus cantonensis Infection

Tsai HC, Chen YH, Yen CM, Chung LY, Wann SR, Lee SS, Chen YS

Steroids are commonly used in patients with eosinophilic meningitis caused by A. cantonensis infections. The mechanism steroids act on eosinophilic meningitis remains unclear. In this mouse experiments, expressions of 14-3-3...
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Diagnosis of Pulmonary Arterial Hypertension in Children by Using Cardiac Computed Tomography

Chen SJ, Huang JH, Lee WJ, Lin MT, Chen YS, Wang JK

OBJECTIVE: To establish diagnostic criteria for pulmonary arterial hypertension (PAH) in children by using parameters obtained through noninvasive cardiac computed tomography (CCT). MATERIALS AND METHODS: We retrospectively measured parameters from CCT...
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Analysis of screening failure of live donation for kidney transplantation: experience of a single medical center in central Taiwan

Chen CH, Feng YY, Chiu KY, Yang CK, Chen YS, Wu JC, Wu MJ

Background: The organ shortage and long waiting list are global burden in treatment for end-stage renal disease (ESRD), thus, live kidney donation is currently available option with superior outcome and...
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Melatonin acts synergistically with pazopanib against renal cell carcinoma cells through p38 mitogen-activated protein kinase-mediated mitochondrial and autophagic apoptosis

Lai CP, Chen YS, Ying TH, Kao CY, Chiou HL, Kao SH, Hsieh YH

Background: Mounting evidence indicates that melatonin has possible activity against different tumors. Pazopanib is an anticancer drug used to treat renal cell carcinoma (RCC). This study tested the anticancer activity...
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Comparison of the trometamol-balanced solution with two other crystalloid solutions for fluid resuscitation of a rat hemorrhagic model

Ting WT, Chang RW, Wang CH, Chen YS, Lee JJ

Currently, the optimal resuscitation fluid remains debatable. Therefore, in the present study, we designed a trometamol-balanced solution (TBS) for use as a resuscitation fluid for hemorrhagic shock. Hemorrhagic shock was...
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