- Contrast-enhanced ultrasonography-based renal blood perfusion in brain-dead donors predicts early graft function
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He W, Xu Y, Gong C, Liu X, Wu Y, Xie X, Chen J, Yu Y, Guo Z, Sun Q
- KMID: 2546451
- Ultrasonography.
- 2023 Oct;42(4):532-543.
- doi: 10.14366/usg.23006
Purpose: The aim of this study was to quantify renal microcirculatory perfusion in braindead donors using contrast-enhanced ultrasonography (CEUS), and to establish an accurate, noninvasive, and convenient index for predicting... -
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- Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats
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Guo S, Chen J, Yang Y, Li X, Tang Y, Gui Y, Chen J, Xu j
- KMID: 2546050
- Neurospine.
- 2023 Sep;20(3):1011-1027.
- doi: 10.14245/ns.2346446.223
Objective: Electroacupuncture (EA) has a definite effect on the treatment of spinal cord injuries (SCIs), but its underlying molecular mechanism remains unclear. Meanwhile, MiR106b-5p is an autophagy- and apoptosis-related microribonucleic... -
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- Perampanel ameliorates nitroglycerin-induced migraine through inhibition of the cAMP/ PKA/CREB signaling pathway in the trigeminal ganglion in rats
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Zhai Q, Wang K, Zhang D, Chen J, Dong X, Pan Y
- KMID: 2544245
- Korean J Pain.
- 2023 Jul;36(3):335-346.
- doi: 10.3344/kjp.23039
Background: Perampanel, a highly selective glutamate AMPA receptor antagonist, is widely used to treat epilepsy. Since the existence of common pathophysiological features between epilepsy and migraine, the aim of this... -
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- Tissue-Engineered 3D In Vitro Disease Models for HighThroughput Drug Screening
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Huskin G, Chen J, Davis T, Jun HW
- KMID: 2544426
- Tissue Eng Regen Med.
- 2023 Jul;20(4):523-538.
- doi: 10.1007/s13770-023-00522-3
During high-throughput drug screening, in vitro models are fabricated and the effects of therapeutics on the models evaluated in high throughput—for example, with automated liquid handling systems and microplate reader-based... -
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- Spine Fractures of Patients with Ankylosing Spondylitis and Diffuse Idiopathic Skeletal Hyperostosis: Fracture Severity and Injury-Related Mortality at a Level I Trauma Center
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Chen SR, Munsch MA, Chen J, Couch BK, Wawrose RA, Oyekan AA, Adjei J, Donaldson WF, Lee JY, Shaw JD
- KMID: 2543162
- Asian Spine J.
- 2023 Jun;17(3):549-558.
- doi: 10.31616/asj.2022.0155
Study Design: Retrospective review of prospectively collected cohort. Purpose: To identify differences in treatment and mortality of spine fractures in patients with ankylosing conditions of the spine. Overview of Literature: Ankylosing... -
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- Coexistence of Subcutaneous Panniculitis-Like T-Cell Lymphoma and Dermatomyositis in a 12-Year-Old Boy
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Wei R, Liu H, Zhang Z, Chen F, Chen J, Xu Q, Yu H, Liang J, Yao Z
- KMID: 2542746
- Ann Dermatol.
- 2023 May;35(Suppl1):S79-S83.
- doi: 10.5021/ad.20.310
Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is an extremely rare, indolent skin malignancy that can be difficult to distinguish from autoimmune disease-associated panniculitides. Here, we describe a 12-year-old boy who was... -
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- Protein Kinase CK2 Modulates the Calcium Sensitivity of Type 3 Small-conductance Calcium-activated Potassium Channels in Colonic Platelet-derived Growth Factor Receptor Alpha-positive Cells From Streptozotocin-induced Diabetic Mice
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Song NN, Huang X, Lu HL, Lu C, Chen J, Xu WX
- KMID: 2541577
- J Neurogastroenterol Motil.
- 2023 Apr;29(2):250-261.
- doi: 10.5056/jnm22052
Background/Aims The gastrointestinal symptom of diabetes mellitus, chronic constipation, seriously affects patients’ life. Whereas, the mechanism of chronic constipation is still ambiguous, resulting in a lack of effective therapies for this... -
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- Inhibition of Fatty Acid β-Oxidation by Fatty Acid Binding Protein 4 Induces Ferroptosis in HK2 Cells Under High Glucose Conditions
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Chen J, Wu K, Lei Y, Huang M, Cheng L, Guan H, Lin J, Zhong M, Wang X, Zheng Z
- KMID: 2541879
- Endocrinol Metab.
- 2023 Apr;38(2):226-244.
- doi: 10.3803/EnM.2022.1604
Background: Ferroptosis, which is caused by an iron-dependent accumulation of lipid hydroperoxides, is a type of cell death linked to diabetic kidney disease (DKD). Previous research has shown that fatty... -
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- Cerebellar Structural Abnormality in Autism Spectrum Disorder: A Magnetic Resonance Imaging Study
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Lu Q, Chen J, Wang Y, Huang L, Jiang Z, Nguchu BA, Chen S, Qiu B, Wang X
- KMID: 2541683
- Psychiatry Investig.
- 2023 Apr;20(4):334-340.
- doi: 10.30773/pi.2022.0254
Objective This study uses structural magnetic resonance imaging to explore changes in the cerebellar lobules in patients with autism spectrum disorder (ASD) and further analyze the correlation between cerebellar structural... -
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- Juvenile Patient with LEOPARD Syndrome: Clinical Profile of a Genetically Confirmed Case
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Wan P, Cheng Y, Chen Z, Chen J
- KMID: 2541123
- Ann Dermatol.
- 2023 Apr;35(2):162-164.
- doi: 10.5021/ad.20.300
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- Breviscapine Ameliorates Fear Extinction and Anxiety in BALB/cJ Mice
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Liang W, Huang J, Yang S, Huang P, Chen J, Chen C, Yang Q, Li F
- KMID: 2540695
- Psychiatry Investig.
- 2023 Mar;20(3):205-211.
- doi: 10.30773/pi.2022.0167
Objective In this research, the influence of breviscapine on anxiety, fear elimination, and aggression and the potential mechanism was investigated. Methods Anxiety and locomotion were analyzed by elevated plus maze and... -
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- Rehmannioside D mitigates disease progression in rats with experimental-induced diminished ovarian reserve via Forkhead Box O1/KLOTHO axis
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Liang Y, Wang H, Chen J, Chen L, Chen X
- KMID: 2539571
- Korean J Physiol Pharmacol.
- 2023 Mar;27(2):167-176.
- doi: 10.4196/kjpp.2023.27.2.167
This study aims to explore the impact of Rehmannioside D (RD) on ovarian functions of rats with diminished ovarian reserve (DOR) and its underlying mechanisms of action. A single injection... -
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- Percutaneous ablation of liver metastases from colorectal cancer: a comparison between the outcomes of ultrasound guidance and CT guidance using propensity score matching
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Luo M, Peng S, Yang G, Lin L, Lu L, Chen J, Zhang F, Gao F
- KMID: 2537421
- Ultrasonography.
- 2023 Jan;42(1):54-64.
- doi: 10.14366/usg.21212
Purpose: The aim of this study was to compare the effectiveness and outcomes of percutaneous ablation guided by ultrasonography (US) and computed tomography (CT) in colorectal liver oligometastases (CLOM). Methods: This... -
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- The association between obesity and glaucoma in older adults: evidence from the China Health and Retirement Longitudinal Study
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Zhao X, Bo Q, Sun J, Chen J, Li T, Huang X, Zhou M, Wang J, Liu W, Sun X
- KMID: 2545047
- Epidemiol Health.
- 2023;45(1):e2023034.
- doi: 10.4178/epih.e2023034
OBJECTIVES: This study evaluated the association between obesity and glaucoma in middle-aged and older people. A population-based retrospective cohort study was conducted using data from the China Health and Retirement... -
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- MiR-182-5p Mediated by Exosomes Derived From Bone Marrow Mesenchymal Stem Cell Attenuates Inflammatory Responses by Targeting TLR4 in a Mouse Model of Myocardial Infraction
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Sun C, Li W, Li Y, Chen J, An H, Zeng G, Wang T, Guo Y, Wang C
- KMID: 2538491
- Immune Netw.
- 2022 Dec;22(6):e49.
- doi: 10.4110/in.2022.22.e49
Exosomes derived from mesenchymal stem cells (MSCs) could protect against myocardial infarction (MI). TLR4 is reported to play an important role in MI, while microRNA-182-5p (miR-182-5p) negatively regulates TLR4 expression.... -
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- Cost-effective donor lung preservation with high-volume continuous perfusate purification in ex vivo lung perfusion
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Wang Z, Wei D, Zhang Y, Dai Z, Yang X, Yue B, Gao F, Liu F, Chen J
- KMID: 2535443
- Korean J Transplant.
- 2022 Nov;36(Supple 1):S226.
- doi: 10.4285/ATW2022.F-3621
Background: Ex vivo lung perfusion is an ideal platform for donor lung evaluation and preservation. Its application in Asia was limited due to the high running costs and potential lung... -
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- Gaseous signal molecule SO2 regulates autophagy through PI3K/ AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes
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Zhao J, Wu Q, Yang T, Nie L, Liu S, Zhou J, Chen J, Jiang Z, Xiao T, Yang J, Chu C
- KMID: 2534529
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):541-556.
- doi: 10.4196/kjpp.2022.26.6.541
Myocardial fibrosis is a key link in the occurrence and development of diabetic cardiomyopathy. Its etiology is complex, and the effect of drugs is not good. Cardiomyocyte apoptosis is an important... -
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- Identification of Long Non-Coding RNAs and Their Target Genes from Mycelium and Primordium in Model Mushroom Schizophyllum commune
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Wu T, Chen J, Jiao C, Hu H, Wu Q, Xie Y
- KMID: 2538261
- Mycobiology.
- 2022 Oct;50(5):357-365.
- doi: 10.1080/12298093.2022.2116819
Schizophyllum commune has emerged as the most promising model mushroom to study developmental stages (mycelium, primordium), which are two primary processes of fruit body development. Long non-coding RNA (lncRNA)... -
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- Outcomes of Anti-CD19 CAR-T Treatment of Pediatric B-ALL with Bone Marrow and Extramedullary Relapse
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Wan X, Yang X, Yang F, Wang T, Ding L, Song L, Miao Y, Wang X, Ma Y, Luo C, Tang J, Gu L, Chen J, Tang Y, Lu J, Li B
- KMID: 2531337
- Cancer Res Treat.
- 2022 Jul;54(3):917-925.
- doi: 10.4143/crt.2021.399
Purpose Anti-CD19 chimeric antigen receptor T-cell immunotherapy (19CAR-T) has achieved impressive clinical results in adult and pediatric relapsed/refractory (r/r) B-lineage acute lymphoblastic leukemia (B-ALL). However, the application and effect of CAR-T... -
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- Clinicopathological and molecular characterization of high-grade endometrial carcinoma with POLE mutation: a single center study
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Yu S, Sun Z, Zong L, Yan J, Yu M, Chen J, Lu Z
- KMID: 2536988
- J Gynecol Oncol.
- 2022 May;33(3):e38.
- doi: 10.3802/jgo.2022.33.e38
Objective The molecular classification system of endometrial carcinoma (EC) in ‘The Cancer Genome Atlas’ is widely acknowledged for its prognostic utility. Subsequently, more simplified classification system that incorporate DNA polymerase epsilon... -
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