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Effect of Pharmacist-Led Intervention in Elderly Patients through a Comprehensive Medication Reconciliation: A Randomized Clinical Trial

Lee S, Yu YM, Han E, Park MS, Lee JH, Chang MJ

Purpose: Polypharmacy can cause drug-related problems, such as potentially inappropriate medication (PIM) use and medication regimen complexity in the elderly. This study aimed to investigate the feasibility and effectiveness of...
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Differences in Resumption of Orthopedic Surgery According to Characteristics of Surgery during COVID-19 Pandemic: National Registry Data

Park HJ, Chang MJ, Kim TW, Chang CB, Kang SB

Background: Healthcare services have been restricted after the coronavirus disease 2019 (COVID-19) outbreak. With the pandemic still ongoing, the patterns of orthopedic surgery might have changed. The purpose of this...
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Comparative Analysis of T-Score Discordance between a Registry-Based Korean Population and Atypical Femoral Fracture Patients of a Single Institution

Choi YS, Kim TW, Jeong JH, Han SB, Chang MJ, Chang CB, Kang SB

Background: The purpose of this study was to analyze the epidemiology of T-score discordance between the spine and femur in the South Korean population and compare the prevalence of T-score...
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Key Foods selection using data from the 7th Korea National Health and Nutrition Examination Survey (2016– 2018)

Lee JS, Shim JS, Kim KN, Lee HS, Chang MJ, Kim HY

Purpose: Key Foods refers to foods that have a high contribution in the nutrient intake of individuals, and exert important effects on their health. This study was undertaken to identify...
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Effect of administration of synbiotics mixture containing Bifidobacterium longum and xylooligosaccharide on fecal microbiota and defecation characteristics in healthy volunteers

Lee JS, Park HS, Kyung M, Jo SE, Chang MJ

Purpose: The effect of prebiotics intake after administration of a synbiotics mixture (a probiotic, Bifidobacterium longum, and a prebiotic, xylooligosaccharide containing sugar [XOS]) on human intestinal microflora and defecation characteristics...
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Analysis of the consumer perception and related education effect on the reduction of sugar for elementary school students in Seoul and Gyeonggi-do

Kim KN, Lee JS, Shim JS, Chung HK, Chung HR, Chang MJ

Purpose: This study examined the effects of nutritional education related to sugar in elementary school children on nutritional knowledge, attitude, and dietary behavior. Methods: A questionnaire survey on the knowledge, attitudes,...
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Posterior condylar offset changes and its effect on clinical outcomes after posteriorsubstituting, fixed-bearing total knee arthroplasty: anterior versus posterior referencing

Chang MJ, Kang SB, Chang CB, n Han DH, Park HJ, Hwang K, Park J, Hwang IU, Lee SA, Oh S

Background: We sought to determine whether there was a difference in the posterior condylar offset (PCO), posterior condylar offset ratio (PCOR) and clinical outcomes following total knee arthroplasty (TKA) with...
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Simultaneous quantification of ticagrelor and its active metabolite, AR-C124910XX, in human plasma by liquid chromatography-tandem mass spectrometry: Applications in steady-state pharmacokinetics in patients

Chae SU, Min KL, Lee CB, Huang Z, Chang MJ, Bae SK

A sensitive and simple liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous quantification of ticagrelor and its active metabolite, AR-C124910XX from 50 µL human plasma using...
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Study on relationship between caffeine intake level and metabolic syndrome and related diseases in Korean adults: 2013 ~ 2016 Korea National Health and Nutrition Examination Survey

Lee JS, Park HS, Han S, Tana G, Chang MJ

PURPOSE: This study examined the relationship between caffeine intake and metabolic syndrome in Korean adults using the 2013 ~ 2016 Korea National Health and Nutrition Examination Survey data (KNHANES). METHODS: The...
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Socioeconomic burden of sugar-sweetened beverages consumption in Korea

Shim JS, Kang NH, Lee JS, Kim KN, Chung HK, Chung HR, Kim HJ, Ahn YS, Chang MJ

BACKGROUND/OBJECTIVES: Excessive sugar consumption may increase the risk for development of several diseases. Although average dietary sugar intake of Koreans is within the recommended level, an increasing trend has been...
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Survey on utilization and demand for national food composition database

Lee HS, Chang MJ, Kim HY, Shim JS, Lee JS, Kim KN

PURPOSE: This study was performed to evaluate the utilization of a current national Food Composition Database (FCDB) and to investigate demand for nutrients that should be added or supplemented in...
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Selection of key foods for the systematic management of a food and nutrient composition database

Shim JS, Lee JS, Kim KN, Lee HS, Kim HY, Chang MJ

BACKGROUND/OBJECTIVES: Food composition databases are necessary for assessing dietary intakes. Developing and maintaining a high quality database is difficult because of the high cost of analyzing nutrient profiles and the...
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Comparing the effects of intake of sugar containing different levels of D-ribose in sugar on glycemic index and blood glucose response in healthy adults

Kim AR, Lee JS, Nam H, Kyung M, Seo S, Chang MJ

PURPOSE: To compare the extent to which three different levels of D-ribose in sugar reduce the glycemic index (GI) and blood glucose response in healthy adults. METHODS: Healthy adults (eight male...
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Anti-inflammatory effect of lycopene in SW480 human colorectal cancer cells

Cha JH, Kim WK, Ha AW, Kim MH, Chang MJ

BACKGROUND/OBJECTIVES: Although the antioxidative effects of lycopene are generally known, the molecular mechanisms underlying the anti-inflammatory properties of lycopene are not fully elucidated. This study aimed to examine the role...
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Effect of xylobiose-sugar mixture on defecation frequency and symptoms in young women with constipation

Lee JS, Kim AR, Nam HK, Kyung M, Jo SE, Chang MJ

PURPOSE: The objective of the study was to investigate the effects of xylobiose-sugar mixture intake on defecation frequency and constipation symptoms in 31 young women with constipation. METHODS: Thirty-one subjects were...
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Effects of JOINS® on the pharmacokinetic profiles of aceclofenac in healthy Korean volunteers: an open-label, multiple-dose, one sequence, two-period study

Kim D, Oh ES, Kim CO, Choi C, Chang MJ, Park MS

JOINS, an herbal anti-arthritic drug, was developed for the treatment and pain relief of knee osteoarthritis. It was approved for use in Korea by the Ministry of Food and Drug...
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Effect of Voriconazole or Itraconazole on the Plasma Concentrations of Tacrolimus in Lung Transplant Recipients

Jung YJ, Yi YS, Ahn JH, Son ES, Park MS, Lee JI, Chang MJ

OBJECTIVE: This study was performed to compare the changes in the blood concentrations of tacrolimus when either itraconazole or voriconazole is together with tacrolimus to prevent or treat invasive aspergillus...
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Food and nutrient intake status of Korean elderly by degree of cognitive function

Kim HY, Lee JS, Youn JC, Chang MJ

PURPOSE: This study was conducted to examine the relationship among cognitive function, nutrition screening initiative (NSI) score, and food intake status. METHODS: A total of 409 subjects aged over 60 years were...
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Effect of varying levels of xylobiose in sugar on glycemic index and blood glucose response in healthy adults

Lee JS, Kim AR, Nam H, Kyung M, Seo S, Chang MJ

PURPOSE: The objective of this study was to compare the effects of three different levels of xylobiose containing sucrose on glycemic indices based on oral glucose tolerance test (OGTT) and...
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Analysis of Satisfaction Level and Comprehension Level between Patient and Pharmacist Group on Patient Counseling Standards

Jeon SG, Yang SW, Choi HJ, Lee JI, Chang MJ

BACKGROUNDS: Patient counseling has been forced since June. 19, 2014. Prior to this, there was no study to try to standardize medication counseling to improve quality. PURPOSE: This study was to...
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