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High-on-Aspirin Platelet Reactivity Differs Between Recurrent Ischemic Stroke Associated With Extracranial and Intracranial Atherosclerosis

Noh KC, Choi Hy, Woo HG, Chang JY, Heo SH, Chang Di, Kim BJ

Background and Purpose Ischemic stroke recurs despite the use of antiplatelet agents. Various mechanisms are involved in recurrence due to intracranial atherosclerosis (ICAS) and extracranial atherosclerosis (ECAS). High-on-aspirin platelet reactivity...
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Long-Term Changes in Post-Stroke Depression, Emotional Incontinence, and Anger

Kwon B, Lee EJ, Park S, Lee JS, Lee MH, Jeong D, Lee D, Kwon HS, Chang DI, Park JH, Cha JK, Heo JH, Sohn SI, Kim DE, Choi-Kwon S, Kim JS

Background and Purpose Long-term changes in post-stroke depression (PSD), post-stroke emotional incontinence (PSEI), and post-stroke anger (PSA) have rarely been studied. Methods This is a sub-study of EMOTION, a randomized, placebo-controlled...
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Real-world evidence on the strategy of olmesartan-based triple single-pill combination in Korean hypertensive patients: a prospective, multicenter, observational study (RESOLVE-PRO)

Sohn IS, Ihm SH, Kim GH, Park SM, Hong BK, Lee CH, Lee SH, Chang DI, Joo SP, Lee SC, Lee Yh, Jeon DW, Jung KT, Rhee SJ, Cho YJ, Kim CJ, I

Background In this prospective, multicenter, non-comparative observational study, the effectiveness and safety of the triple single-pill combination (SPC) of olmesartan/amlodipine/hydrochlorothiazide (OM/AML/HCTZ) were evaluated in a real clinical practice setting in Korean...
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Causes, Risk Factors, and Clinical Outcomes of Stroke in Korean Young Adults: Systemic Lupus Erythematosus is Associated with Unfavorable Outcomes

Kwon HS, Kim YS, Lee JM, Koh SH, Kim HY, Kim C, Lee SH, Jung KH, Kim YD, Kwon HM, Kim BJ, Kim JM, Kim BJ, Heo SH, Chang DI, on Behalf of the SKY Investigators

Background and Purpose: The incidence of ischemic stroke (IS) in young adults is increasing, and the associated large socioeconomic impact makes understanding IS in young adults important. We investigated the...
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Reliability and Clinical Utility of Machine Learning to Predict Stroke Prognosis: Comparison with Logistic Regression

Jang SK, Chang JY, Lee JS, Lee EJ, Kim YH, Han JH, Chang DI, Cho HJ, Cha JK, Yu KH, Jung JM, Ahn SH, Kim DE, Sohn SI, Lee JH, Park KP, Kwon SU, Kim JS, Kang DW, KOSNI Investigators

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Clinical Characteristics of Non-Amnestic Mild Cognitive Impairment: A Single-Center Experience

Oh E, Shin CW, Kim BJ, Hwang KJ, Heo SH, Ahn TB, Chang DI, Yoon SS, Park KC, Lee JS

BACKGROUND: To evaluate the clinical characteristics of patients with non-amnestic mild cognitive impairment (naMCI) in a memory disorder clinic at a single center. METHODS: A retrospective study was conducted involving 312...
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Differences in Therapeutic Responses and Factors Affecting Post-Stroke Depression at a Later Stage According to Baseline Depression

Lee EJ, Kim JS, Chang DI, Park JH, Ahn SH, Cha JK, Heo JH, Sohn SI, Lee BC, Kim DE, Kim HY, Kim S, Kwon DY, Kim J, Seo WK, Lee J, Park SW, Koh SH, Kim JY, Choi-Kwon , Kim MS, Lee JS, the EMOTION Investigators

BACKGROUND AND PURPOSE: The pathophysiology of post-stroke depression (PSD) is complex and may differ according to an individual’s mood immediately after stroke. Here, we compared the therapeutic response and clinical...
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Ethnic Differences in Intracranial Artery Tortuosity: A Possible Reason for Different Locations of Cerebral Atherosclerosis

Kim BJ, Lee KM, Lee SH, Kim HG, Kim EJ, Heo SH, Chang DI, Kim JS

No abstract available.
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Basilar Artery Plaque and Pontine Infarction Location and Vascular Geometry

Kim BJ, Lee KM, Kim HY, Kim YS, Koh SH, Heo SH, Chang DI

BACKGROUND AND PURPOSE: Subclinical atherosclerotic plaques are common in patients with pontine infarctions (PIs) but without basilar artery (BA) stenosis. We hypothesized that BA plaque locations may differ by PI...
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Differences between the Molecular Mechanisms Underlying Ruptured and Non-Ruptured Carotid Plaques, and the Significance of ABCA1

Heo SH, Lee EH, Park HH, Kim BJ, Youn HC, Kim YS, Kim HY, Koh SH, Chang DI

BACKGROUND AND PURPOSE: Carotid plaques are a strong risk factor for ischemic stroke, and plaque rupture poses an even higher risk. Although many studies have investigated the pathogenic mechanisms of...
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Early-stage Alcoholic Cerebellar Degeneration: Diagnostic Imaging Clues

Lee JH, Heo SH, Chang DI

No abstract available.
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Preoperative Coronary Stenosis Is a Determinant of Early Vascular Outcome after Carotid Endarterectomy

Kim JH, Heo SH, Nam HJ, Youn HC, Kim EJ, Lee JS, Kim YS, Kim HY, Koh SH, Chang DI

BACKGROUND AND PURPOSE: The benefit of carotid endarterectomy (CEA) is directly influenced by the risk of perioperative adverse outcomes. However, patient-level risks and predictors including coronary stenosis are rarely evaluated,...
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Impairments of Inhibitory Motor Control in Cerebral Cortical Infarction

Lee JS, Heo SH, Chang DI

No abstract available.
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Isolated Weakness of Radial-side Fingers Due to a Small Cortical Infarction

Hwang KJ, Park KC, Chang DI, Yoon SS

Predominant involvement of a particular group of fingers due to a central nervous system lesion has been described as pseudoperipheral palsy. Two patients visited our hospital with isolated weakness of...
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Sleep Disturbances and Predictive Factors in Caregivers of Patients with Mild Cognitive Impairment and Dementia

Lee D, Heo SH, Yoon SS, Chang DI, Lee S, Rhee HY, Ku BD, Park KC

BACKGROUND AND PURPOSE: We examined the characteristics of sleep disturbances and sleep patterns in the caregivers of patients with amnestic mild cognitive impairment (aMCI) and dementia. METHODS: We prospectively studied 132...
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Superior Rectus-Levator Palpebrae Complex Myositis Presenting as Isolated Painless Ptosis

Lee D, Heo SH, Lee JH, Kwon YN, Nam H, Lee J, Park KC, Ahn TB, Yoon SS, Chang DI, Chung KC

  • KMID: 2343512
  • J Korean Neurol Assoc.
  • 2013 Nov;31(4):286-288.
No abstract available.
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Recurrent Cerebral Infarction in Polycythemia Vera

Lee SH, Lee J, Nam H, Heo SH, Chang DI

  • KMID: 2343507
  • J Korean Neurol Assoc.
  • 2013 Nov;31(4):266-269.
Polycythemia vera (PV) is a chronic myeloproliferative disorder that is characterized by increased production of leukocytes, erythrocytes, and platelets. Arterial and venous thromobotic complications are common in the clinical course...
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Bilateral Striopallidodentate Calcinosis in Chromosome 22q11.2 Deletion Syndrome

Jung YJ, Kwon Y, Kwon YC, Lee D, Lee SH, Heo SH, Chang DI

  • KMID: 2191524
  • J Korean Neurol Assoc.
  • 2012 Nov;30(4):305-308.
Symptomatic bilateral striopallidodentate calcinosis is required to identify the underlying causes. Disorder of calcium metabolism, such as hypoparathyroidism is the most common cause. We report a patient with hypoparathyroidism induced...
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Magnetic Resonance Findings in Two Episodes of Repeated Cerebral Fat Embolisms in a Patient with Autologous Fat Injection into the Face

Lee KM, Kim EJ, Jahng GH, Chang DI

We report magnetic resonance image (MRI) and magnetic resonance spectroscopy (MRS) findings in a patient of cerebral fat embolism (CFE) occurred in a 26-year-old woman after an autologous fat injection...
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Prediction of Hemorrhagic Transformation and Functional Outcome Using HAT Score in Acute Ischemic Stroke Patients Treated with Intravenous Alteplase

Heo SH, Yi SH, Lee D, Hwang KJ, Jung YJ, Park KC, Ahn TB, Yoon SS, Chung KC, Chang DI

  • KMID: 1966505
  • J Korean Neurol Assoc.
  • 2012 May;30(2):110-115.
BACKGROUND: Intravenous thrombolysis with alteplase is the most effective therapy for acute ischemic stroke, but hemorrhagic transformation (HT) is a potentially dangerous complication of such thrombolysis. Few studies have investigated...
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