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Human Epidermal Growth Factor Receptor 2-positive Mucinous Carcinoma with Signet Ring Cell Differentiation, Which Showed Complete Response after Neoadjuvant Chemotherapy

Jang Y, Cho EY, Cho SY

Mucinous carcinoma (MC) is a rare subtype of breast cancer, which is composed of tumor cells floating in the abundant extracellular mucin. This form of cancer is usually estrogen receptor/progesterone...
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Metabolic Reprogramming by the Excessive AMPK Activation Exacerbates Antigen-Specific Memory CD8⁺ T Cell Differentiation after Acute Lymphocytic Choriomeningitis Virus Infection

Son J, Cho YW, Woo YJ, Baek YA, Kim EJ, Cho Y, Kim JY, Kim BS, Song JJ, Ha SJ

During virus infection, T cells must be adapted to activation and lineage differentiation states via metabolic reprogramming. Whereas effector CD8⁺ T cells preferentially use glycolysis for their rapid proliferation, memory...
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rBMSCs/ITGA5B1 Promotes Human Vascular Smooth Muscle Cell Differentiation via Enhancing Nitric Oxide Production

Zhang Y, Ding J, Xu C, Yang H, Xia P, Ma S, Chen H

BACKGROUND AND OBJECTIVES: Previous studies have shown that integrins alpha5beta1 (ITGA5B1) gene-modified rat bone marrow mesenchymal stem cells (rBMSCs) could prevent cell anoikis and increase the nitric oxide (NO) production....
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Effect of Resveratrol on Cell Differentiation and Mineralization in Cultured Odontoblasts

Shin SH, Kim JS, Kim SG, Go DS, Yu SK, Kim CS, Park JC, Kim DK

Resveratrol (3,4′,5,-trihydroxystilbene), a phytoalexin present in grapes, exerts a variety of actions to reduce superoxides, prevents diabetes mellitus, and inhibits inflammation. Resveratrol acts as a chemo-preventive agent and induces apoptotic...
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The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway

Cheng Z, Zhang Q, Yin A, Feng M, Li H, Liu H, Li Y, Qian L

In a previous study, we screened thousands of long non-coding RNAs (lncRNAs) to assess their potential relationship with congenital heart disease (CHD). In this study, uc.4 attracted our attention because...
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Effect of remifentanil on pre-osteoclast cell differentiation in vitro

Jeon HO, Choi IS, Yoon JY, Kim EJ, Yoon JU, Cho AR, Kim HJ, Kim CH

BACKGROUND: The structure and function of bone tissue is maintained through a constant remodeling process, which is maintained by the balance between osteoblasts and osteoclasts. The failure of bone remodeling...
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A Rare Case of Mesothelioma Showing Micropapillary and Small Cell Differentiation with Aggressive Behavior

Cha YJ, Kim B, Han J, Yi CA, Zo JI

No abstract available.
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miR-18a-5p MicroRNA Increases Vascular Smooth Muscle Cell Differentiation by Downregulating Syndecan4

Kee HJ, Kim GR, Cho SN, Kwon JS, Ahn Y, Kook H, Jeong MH

BACKGROUND AND OBJECTIVES: Differentiation and de-differentiation of vascular smooth muscle cells (VSMCs) are important events in atherosclerosis and restenosis after angioplasty. MicroRNAs are considered a key regulator in cellular processes...
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NF-kappaB Activation in T Helper 17 Cell Differentiation

Park SH, Cho G, Park SG

CD28/T cell receptor ligation activates the NF-kappaB signaling cascade during CD4 T cell activation. NF-kappaB activation is required for cytokine gene expression and activated T cell survival and proliferation. Recently,...
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Comparative Analysis of Squamous Cell Differentiation by Histologic Subtypes in Basal Cell Carcinoma

Oh ST, Chong SJ, Park CJ, Park YM, Cho SH, Lee JY, Kim JW, Kim SY, Cho BK

  • KMID: 2087043
  • Korean J Dermatol.
  • 2005 Nov;43(11):1475-1481.
BACKGROUND: There has been no general agreement on classifying basal cell carcinoma (BCC), and little is known about the squamous cell differentiations of each subtype of BCC. BCC is a...
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Stem Cell In Adult Pancreas: Its Activation and Induction of Beta Cell Differentiation

Kim SY, Kim EH, Lee S, Lee KO, Min BH, Park IS

  • KMID: 2030755
  • Korean J Anat.
  • 2004 Apr;37(2):117-122.
Stem cells in adult pancreas and their specific marker are poorly characterized. We hypothesized that pancreatic stem cells could evolve from the duct system in response to neogenic stimulation. Following...
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Trial for Drug Susceptibility Testing of Mycobacterium tuberculosis with Live and Dead Cell Differentiation

Ryu SW, Kim HH, Bang MN, Park YK, Park SN, Shim YS, Kang S, Bai GH

BACKGROUND: The resurgence of tuberculosis and outbreaks of multidrug resistant (MDR) tuberculosis have increased the emphasis for the development of new susceptibility testing of the Mycobacterium tuberculosis for the effective...
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In vitro Neural Cell Differentiation of Genetically Modified Human Embryonic Stem Cells Expressing Tyrosine Hydroxylase

Shin HA, Kim EY, Lee KS, Cho HY, Kim YS, Lee WD, Park S, Lim JH

  • KMID: 1891202
  • Korean J Fertil Steril.
  • 2004 Mar;31(1):67-74.
OBJECTIVE: This study was to examine in vitro neural cell differentiation pattern of the genetically modified human embryonic stem cells expressing tyrosine hydroxylase (TH). MATERIALS AND METHODS: Human embryonic stem (hES,...
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In Vitro Neural Cell Differentiation Derived from Human Embryonic Stem Cells: Effects of PDGF-bb and BDNF on the Generation of Functional Neurons

Cho HJ, Kim EY, Lee YJ, Choi KH, Ahn SY, Park SP, Lim JH

  • KMID: 1864600
  • Korean J Fertil Steril.
  • 2002 Jun;29(2):117-127.
OBJECTIVE: This study was to investigate the generation of the functional neuron derived from human embryonic stem(hES,MB03) cells on in vitro neural cell differentiation system. METHODS: For neural progenitor cell formation...
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Studies on the Determining Factors at Each Stage of Germinal Center B Cell Differentiation

Choe JS, Choi YS

  • KMID: 1550787
  • Korean J Immunol.
  • 1999 Jun;21(2):159-164.
To delineate the individual role of follicular dendritic cells (FDC) and T cells at each stage of GC B cell differentiation at the clonal level and to analyze the signals...
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