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Anaplastic Transformation of Metastatic Papillary Thyroid Carcinoma in a Cervical Lymph Node: a Timeline and Short Review

Cinamon U, Horev Y, Vaknine H

Anaplastic thyroid cancer (ATC) is accepted as the transformation of a pre-existing glandular papillary thyroid carcinoma (PTC). Anaplastic transformation of a neck PTC metastasis in a lymph node is extraordinary....
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Survival outcomes of adjuvant radiotherapy and chemotherapy in women with stage I serous papillary and clear cell carcinoma of the endometrium: a Korean multicenter study

Kim M, Kwon BS, Chang HK, Lee S, Chang SJ, Choi JY, Park SY, Lee M, Ryu HS, Kim YB

OBJECTIVE: To compare the survival outcomes of adjuvant radiotherapy and chemotherapy in women with uterine-confined endometrial cancer with uterine papillary serous carcinoma (UPSC) or clear cell carcinoma (CCC). METHODS: Medical records...
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Is the ovarian preservation safe in young women with stages IB–IIA villoglandular adenocarcinoma of the uterine cervix?

Ju UC, Kang WD, Kim SM

OBJECTIVE: Because villoglandular adenocarcinoma (VGA) of the uterine cervix has favorable features and outcomes, patients receive less radical surgery and young women preserve their ovaries. We aimed to evaluate the...
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Management of Low-Risk Papillary Thyroid Cancer

Iñiguez-Ariza NM, Brito JP

The incidence of thyroid cancer has increased, mainly due to the incidental finding of low-risk papillary thyroid cancers (PTC). These malignancies grow slowly, and are unlikely to cause morbidity and...
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Diagnosis and treatment of low-risk papillary thyroid microcarcinoma

Moon JH, Park YJ

Recent guidelines for the treatment of thyroid nodules and differentiated thyroid cancer include active surveillance as an alternative option for the treatment of low-risk papillary thyroid microcarcinoma (PTMC). PTMC is...
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Programmed Death-Ligand 1 Expression and Its Correlation with Lymph Node Metastasis in Papillary Thyroid Carcinoma

An HJ, Ko GH, Lee JH, Lee JS, Kim DC, Yang JW, Kim MH, Kim JP, Jung EJ, Song DH

BACKGROUND: The immunotherapeutic role of programmed death-ligand 1 (PD-L1) in life expectancy in many cancers has been highlighted. However, data regarding PD-L1 expression in papillary thyroid carcinoma (PTC) are limited....
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Cohexisting Medullary and Papillary Thyroid Cancer

Dionigi G, Tanda ML, Piantanida E, Uccella S, La Rosa S, Inversini , Lavazza M, Pappalardo V, Sessa F, Xiaoli L

PURPOSE: Papillary thyroid carcinomas (PTCs) and medullary thyroid carcinomas (MTCs) have always been considered different in terms of their incidence rates, cell origins, and histopathological features. Simultaneous occurrence of both...
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The Diagnostic Utility of Ultrasonography, CT and PET/CT for the Preoperative Evaluation of Cervical Lymph Node Metastasis in Papillary Thyroid Cancer Patients

Kim Y, Lee T, Park D

PURPOSE: To compare the diagnostic utility of ultrasonography (US), CT and positron emission tomography/CT (PET/CT) in the preoperative evaluation of cervical lymph node metastasis in patients with papillary thyroid carcinoma. MATERIALS...
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The follicular variant of papillary thyroid carcinoma: characteristics of preoperative ultrasonography and cytology

Yoon JH, Kwon HJ, Kim EK, Moon HJ, Kwak JY

PURPOSE: The goal of this study was to validate the ultrasonography (US) and cytopathological features that are used in the diagnosis of the follicular variant of papillary thyroid carcinoma (FVPTC)...
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A Case of Papillary Squamous Cell Carcinoma Which Associated with Inverted Papilloma in Sinonasal Cavity

Gu PM, Park SK, Jung SJ

According to the classification of World Health Organization, papillary squamous cell carcinoma is a variant of squamous cell carcinoma. This is a malignancy rarely found in the upper aerodigestive tract,...
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A Case of Multifocal Papillary Thyroid Carcinoma Consisting of One Encapsulated Follicular Variant with BRAF K601E Mutation and Three Conventional Types with BRAF V600E Mutation

Kim WY, Ko YS, Hwang TS, Han HS, Lim SD, Kim WS, Oh SY

  • KMID: 2277449
  • Korean J Pathol.
  • 2013 Jun;47(3):293-298.
Multifocal papillary thyroid carcinoma (mPTC) comprises about 20-30% of PTC. In mPTC, individual tumor foci can be identical or frequently composed of different histological types including follicular, solid, tall-cell or...
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Correlation of Immunohistochemical Markers and BRAF Mutation Status with Histological Variants of Papillary Thyroid Carcinoma in the Korean Population

Min HS, Lee C, Jung KC

Several pathologic characteristics are associated with an adverse clinical outcome in papillary thyroid carcinoma (PTC), including the histological variant. This study aimed to investigate immunohistochemical expression and BRAF mutation status...
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Concurrent Papillary Carcinoma Arising in Thyroglossal Duct Cyst and Thyroid Gland: A Case Report

Kim KT, Kim YJ, Kim SJ, Cho YU, Jeon YS, Kim YJ

The occurrence and diagnosis of thyroglossal duct carcinoma is very rare. The synchronous occurrence of papillary carcinomas arising in a thyroglossal duct cyst (TGDC) and thyroid gland is extremely rare....
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Tumor Margin Histology Predicts Tumor Aggressiveness in Papillary Thyroid Carcinoma: A Study of 514 Consecutive Patients

Kim KJ, Hong SW, Lee YS, Kim BW, Lee SC, Chang HS, Park CS

Histologic patterns at tumor margins may be related to prognosis in several malignancies. We investigated tumor aggressiveness with respect to tumor margin histology in patients with papillary thyroid carcinoma (PTC)....
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Effect of Selective Cyclooxygenase 2 Inhibitor in TCDD Pre-exposed Thyroid Papillary Carcinoma Cell Line

Kim HS, Ahn KS, Lee JH, Chae YS, Won NH, Choi JS, Kim CH

  • KMID: 2277513
  • Korean J Pathol.
  • 2011 Feb;45(1):1-8.
BACKGROUND: Cyclooxygenase 2 (COX-2) is related to carcinogenesis and progression of cancer. COX-2 has been detected in thyroid cancer. This suggests that COX-2 inhibitor may be useful to control the...
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Primary Follicular Carcinoma Arising in Ectopic Thyroid Tissue of the Lateral Neck: A Case Report

Oh SW, Park DW, Kim SY, Hahm CK, Lee YJ, Lee SR, Pyo JY, Oh YH, Park YW

Ectopic thyroid tissue in the lateral neck is an uncommon congenital anomaly, and the occurrence of primary follicular carcinoma in this ectopic thyroid tissue is very rare. We report here...
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Composite Follicular Variant of Papillary Carcinoma and Mucoepidermoid Carcinoma of Thyroid Gland: A Case Report

Jung YH, Kang MS

A 50-yr-old male presented a thyroid mass with dysphasia and hoarseness. He underwent total thyroidectomy and neck node dissection. Pathologically, the tumor had two distinct tumor components with intermingled areas:...
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The Frequency of BRAF Mutation in Very Small Papillary Thyroid Carcinomas

Kim T, Roh JH, Park HJ, Kwon JE, Kang SY, Choi YL, Oh YL

  • KMID: 1837535
  • Korean J Pathol.
  • 2010 Jun;44(3):308-314.
BACKGROUND: Papillary thyroid carcinoma (PTC) is the most common malignant tumor of the thyroid and BRAF (V600E) is the most frequent genetic alteration in PTCs. The aim of this study...
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Microvessel and Lymphatic Vessel Density and VEGFR-3 Expression of Papillary Thyroid Carcinoma with Comparative Analysis of Clinicopathological Characteristics

Cheong H, Kang H, Kim HK, Bae JY, Song DE, Cho MS, Sung SH, Han WS, Koo H

  • KMID: 1837527
  • Korean J Pathol.
  • 2010 Jun;44(3):243-251.
BACKGROUND: This study was done to see if there were correlations between anatomic and molecular parameters such as microvessel density (MVD), lymphatic vessel density (LVD), and vascular endothelial growth factor...
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Availability of Immunohistochemistry in the Diagnosis of Follicular Variant of Papillary Thyroid Carcinoma

Jeong JY, Jang JS, Sohn YK, Jung JH, Chun YK, Park JY

  • KMID: 2277623
  • Korean J Pathol.
  • 2010 Feb;44(1):48-55.
BACKGROUND: Making the diagnosis of the follicular variant of papillary thyroid carcinoma (FVPTC) is often difficult, and there are no accurate immunohistochemical or molecular markers. The purpose of this study...
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