- In Memoriam: Waun Ki Hong, M.D. (August 13, 1942-January 2, 2019)
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Kim HK
- KMID: 2464388
- Cancer Res Treat.
- 2019 Apr;51(2):415-416.
- doi: 10.4143/crt.2019.149
No abstract available. -
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- Prediction of Cancer Incidence and Mortality in Korea, 2019
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Jung KW, Won YJ, Kong HJ, Lee ES
- KMID: 2464390
- Cancer Res Treat.
- 2019 Apr;51(2):431-437.
- doi: 10.4143/crt.2019.139
PURPOSE: This study aimed to report on cancer incidence and mortality for the year 2019 to estimate Korea's current cancer burden. MATERIALS AND METHODS: Cancer incidence data from 1999 to 2016... -
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- Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2016
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Jung KW, Won YJ, Kong HJ, Lee ES, The Community of Population-Based Regional Cancer Registries
- KMID: 2464389
- Cancer Res Treat.
- 2019 Apr;51(2):417-430.
- doi: 10.4143/crt.2019.138
PURPOSE: This study presents the 2016 nationwide cancer statistics in Korea, including cancer incidence, survival, prevalence, and mortality. MATERIALS AND METHODS: Cancer incidence data from 1999 to 2016 were obtained from... -
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- Genome-Wide Association of Genetic Variation in the PSCA Gene with Gastric Cancer Susceptibility in a Korean Population
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Park B, Yang S, Lee J, Woo HD, Choi IJ, Kim YW, Ryu KW, Kim YI, Kim J
- KMID: 2464420
- Cancer Res Treat.
- 2019 Apr;51(2):748-757.
- doi: 10.4143/crt.2018.162
PURPOSE: Half of the world's gastric cancer cases and the highest gastric cancer mortality rates are observed in Eastern Asia. Although several genome-wide association studies (GWASs) have revealed susceptibility genes... -
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- Pan-Pim Kinase Inhibitor AZD1208 Suppresses Tumor Growth and Synergistically Interacts with Akt Inhibition in Gastric Cancer Cells
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Lee M, Lee KH, Min A, Kim J, Kim S, Jang H, Lim JM, Kim SH, Ha DH, Jeong WJ, Suh KJ, Yang YW, Kim TY, Oh DY, Bang YJ, Im SA
- KMID: 2464392
- Cancer Res Treat.
- 2019 Apr;51(2):451-463.
- doi: 10.4143/crt.2017.341
PURPOSE: Pim kinases are highly conserved serine/threonine kinases, and different expression patterns of each isoform (Pim-1, Pim-2, and Pim-3) have been observed in various types of human cancers, including gastric... -
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- A Comprehensive Assessment of the Racial and Ethnic Disparities in the Incidence of Gastric Cancer in the United States, 1992-2014
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Yao Q, Qi X, Cheng W, Xie SH
- KMID: 2464399
- Cancer Res Treat.
- 2019 Apr;51(2):519-529.
- doi: 10.4143/crt.2018.146
PURPOSE: This study aimed to evaluate the racial and ethnic disparities in the incidence of gastric cancer and their temporal trends in the United States. MATERIALS AND METHODS: Using data from... -
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- Diabetes Medication Use in Association with Survival among Patients of Breast, Colorectal, Lung, or Gastric Cancer
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Baglia ML, Cui Y, Zheng T, Yang G, Li H, You M, Xu L, Murff H, Gao YT, Zheng W, Xiang YB, Shu XO
- KMID: 2464401
- Cancer Res Treat.
- 2019 Apr;51(2):538-546.
- doi: 10.4143/crt.2017.591
PURPOSE: Studies suggest that regular use of metformin may decrease cancer mortality. We investigated the association between diabetes medication use and cancer survival. MATERIALS AND METHODS: The current study includes 633... -
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- Comparative Effectiveness of Abdominal versus Laparoscopic Radical Hysterectomy for Cervical Cancer in the Postdissemination Era
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Kim JH, Kim K, Park SJ, Lee JY, Kim K, Lim MC, Kim JW
- KMID: 2464424
- Cancer Res Treat.
- 2019 Apr;51(2):788-796.
- doi: 10.4143/crt.2018.120
PURPOSE: Despite the benefits of minimally invasive surgery for cervical cancer, there are a lack of randomized trials comparing laparoscopic radical hysterectomy and abdominal radical hysterectomy. We compared morbidity, cost... -
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- Health-Related Quality of Life Changes in Prostate Cancer Patients after Radical Prostatectomy: A Longitudinal Cohort Study
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Shin DW, Lee SH, Kim TH, Yun SJ, Nam JK, Jeon SH, Park SC, Jung SI, Park JH, Park J
- KMID: 2464403
- Cancer Res Treat.
- 2019 Apr;51(2):556-567.
- doi: 10.4143/crt.2018.221
PURPOSE: Health-related quality of life (HRQOL) information related to radical prostatectomy (RP) is valuable for prostate cancer (PC) patients needing to make treatment decisions. We aimed to investigate HRQOL change... -
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- Dynamics of Soluble Programmed Death-Ligand 1 (sPDL1) during Chemotherapy and Its Prognostic Implications in Cancer Patients: Biomarker Development in Immuno-oncology
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Ha H, Bang JH, Nam AR, Park JE, Jin MH, Bang YJ, Oh DY
- KMID: 2464428
- Cancer Res Treat.
- 2019 Apr;51(2):832-840.
- doi: 10.4143/crt.2018.311
PURPOSE: The soluble programmed death-ligand 1 (sPDL1) has immunosuppressive activity and is a candidate biomarker for immuno-oncology drug development. In this study, we measured sPDL1 at pre- and post-chemotherapy and... -
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- Combination Treatment of Stereotactic Body Radiation Therapy and Immature Dendritic Cell Vaccination for Augmentation of Local and Systemic Effects
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Choi CW, Jeong MH, Park YS, Son CH, Lee HR, Koh EK
- KMID: 2464393
- Cancer Res Treat.
- 2019 Apr;51(2):464-473.
- doi: 10.4143/crt.2018.186
PURPOSE: The purpose of this study was to investigate the efficacy of stereotactic body radiation therapy (SBRT) as a tumor-associated antigen (TAA) presentation method for dendritic cell (DC) sensitization and... -
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- Upregulation of PITX2 Promotes Letrozole Resistance Via Transcriptional Activation of IFITM1 Signaling in Breast Cancer Cells
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Xu YY, Yu HR, Sun JY, Zhao Z, Li S, Zhang XF, Liao ZX, Cui MK, Li J, Li C, Zhang Q
- KMID: 2464405
- Cancer Res Treat.
- 2019 Apr;51(2):576-592.
- doi: 10.4143/crt.2018.100
PURPOSE: Although the interferon α (IFNα) signaling and the paired-like homeodomain transcription factor 2 (PITX2) have both been implicated in the progression of breast cancer (BCa), it remains obscure whether... -
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- Correlation of Androgen Deprivation Therapy with Cognitive Dysfunction in Patients with Prostate Cancer: A Nationwide Population-Based Study Using the National Health Insurance Service Database
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Tae BS, Jeon BJ, Shin SH, Choi H, Bae JH, Park JY
- KMID: 2464406
- Cancer Res Treat.
- 2019 Apr;51(2):593-602.
- doi: 10.4143/crt.2018.119
PURPOSE: The purpose of this study was to evaluate the association of androgen deprivation therapy (ADT) with cognitive dysfunction. MATERIALS AND METHODS: Using the National Health Insurance Service database of the... -
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- Prognostic Role and Clinical Association of Tumor-Infiltrating Lymphocyte, Programmed Death Ligand-1 Expression with Neutrophil-Lymphocyte Ratio in Locally Advanced Triple-Negative Breast Cancer
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Lee J, Kim DM, Lee A
- KMID: 2464411
- Cancer Res Treat.
- 2019 Apr;51(2):649-663.
- doi: 10.4143/crt.2018.270
PURPOSE: Tumor-infiltrating lymphocyte (TIL), programmed death-ligand 1 (PD-L1) expression and neutrophil-to-lymphocyte ratio (NLR) is associated to immunogenicity and prognosis of breast cancer. We analyzed baseline NLR, changes of NLR, TIL,... -
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- Efficacy and Safety of Afatinib for EGFR-mutant Non-small Cell Lung Cancer, Compared with Gefitinib or Erlotinib
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Kim Y, Lee SH, Ahn JS, Ahn MJ, Park K, Sun JM
- KMID: 2464397
- Cancer Res Treat.
- 2019 Apr;51(2):502-509.
- doi: 10.4143/crt.2018.117
PURPOSE: We tried to evaluate whether there are any specific features in treatment outcomes of firstline afatinib in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC),... -
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- Immunohistochemistry Biomarkers Predict Survival in Stage II/III Gastric Cancer Patients: From a Prospective Clinical Trial
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Kim MH, Zhang X, Jung M, Jung I, Park HS, Beom SH, Kim HS, Rha SY, Kim H, Choi YY, Son T, Kim HI, Cheong JH, Hyung WJ, Noh SH, Chung HC
- KMID: 2464427
- Cancer Res Treat.
- 2019 Apr;51(2):819-831.
- doi: 10.4143/crt.2018.331
PURPOSE: Identification of biomarkers to predict recurrence risk is essential to improve adjuvant treatment strategies in stage II/III gastric cancer patients. This study evaluated biomarkers for predicting survival after surgical... -
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- Application of the International Metastatic Renal Cell Carcinoma Database Consortium and Memorial Sloan Kettering Cancer Center Risk Models in Patients with Metastatic Non-Clear Cell Renal Cell Carcinoma: A Multi-Institutional Retrospective Study Using the Korean Metastatic Renal Cell Carcinoma Registry
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Kim JK, Kim SH, Song MK, Joo J, Seo SI, Kwak C, Jeong CW, Song C, Hwang EC, Seo IY, Lee H, Hong SH, Park JY, Chung J, Korean Renal Cell Carcinoma Study Group
- KMID: 2464421
- Cancer Res Treat.
- 2019 Apr;51(2):758-768.
- doi: 10.4143/crt.2018.421
PURPOSE: The International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) and the Memorial Sloan Kettering Cancer Center (MSKCC) risk models were developed predominantly with clear cell renal cell carcinoma (RCC).... -
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- The Clinical Value of PELP1 for Breast Cancer: A Comparison with Multiple Cancers and Analysis in Breast Cancer Subtypes
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Wang X, Tsang JY, Lee MA, Ni YB, Tong JH, Chan SK, Cheung SY, To KF, Tse GM
- KMID: 2464416
- Cancer Res Treat.
- 2019 Apr;51(2):706-717.
- doi: 10.4143/crt.2018.316
PURPOSE: Proline, glutamic acid, and leucine-rich protein 1 (PELP1), a novel nuclear receptor (NR) co-regulator, is highly expressed in breast cancer. We investigated its expression in breast cancer subtypes, in... -
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- Prediction of Acquired Taxane Resistance Using a Personalized Pathway-Based Machine Learning Method
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Kim YR, Kim D, Kim SY
- KMID: 2464413
- Cancer Res Treat.
- 2019 Apr;51(2):672-684.
- doi: 10.4143/crt.2018.137
PURPOSE: This study was conducted to develop and validate an individualized prediction model for automated detection of acquired taxane resistance (ATR). MATERIALS AND METHODS: Penalized regression, combinedwith an individualized pathway score... -
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- Disulfiram, a Re-positioned Aldehyde Dehydrogenase Inhibitor, Enhances Radiosensitivity of Human Glioblastoma Cells In Vitro
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Koh HK, Seo SY, Kim JH, Kim HJ, Chie EK, Kim SK, Kim IH
- KMID: 2464415
- Cancer Res Treat.
- 2019 Apr;51(2):696-705.
- doi: 10.4143/crt.2018.249
PURPOSE: Glioblastoma, the most common brain tumor in adults, has poor prognosis. The purpose of this study was to determine the effect of disulfiram (DSF), an aldehyde dehydrogenase inhibitor, on... -
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