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MET-Amplified Intramucosal Gastric Cancer Widely Metastatic after Complete Endoscopic Submucosal Dissection

Lee D, Kim YC, Lee KM, Yoon JK, Kim YB

  • Cancer Res Treat.
  • 2015 Jan;47(1):120-125.
  • doi: 10.4143/crt.2013.137
Intramucosal gastric cancer (IGC) is associated with a very low risk of lymph node metastasis; thus it is the main candidate for minimally invasive surgical procedures, such as endoscopic submucosal...
Long-Term Survival after T-cell Lymphoblastic Lymphoma Treated with One Cycle of Hyper-CVAD Regimen

Ryu IH, Cho IS, Ryu AJ, Kim MG, Jeon JW, Kim JS, Lee JJ, Choi JW, Kang DW

  • Cancer Res Treat.
  • 2015 Jan;47(1):115-119.
  • doi: 10.4143/crt.2013.122
T-lymphoblastic lymphoma (T-LBL) is a rare form of aggressive non-Hodgkin's lymphoma. The standard approach for management of T-LBL involves intensive multiagent chemotherapy regimens for induction and consolidation phases with central...
Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer

Kim CH, Shin JE, Kim HJ, Lee KY

  • Cancer Res Treat.
  • 2015 Jan;47(1):110-114.
  • doi: 10.4143/crt.2013.079
We report on a patient with brain metastasis involving bilateral internal auditory canal from non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosed with NSCLC (T2aN1M0) complained...
TGF-beta Suppresses COX-2 Expression by Tristetraprolin-Mediated RNA Destabilization in A549 Human Lung Cancer Cells

Kang S, Min A, Im SA, Song SH, Kim SG, Kim HA, Kim HJ, Oh DY, Jong HS, Kim TY, Bang YJ

  • Cancer Res Treat.
  • 2015 Jan;47(1):101-109.
  • doi: 10.4143/crt.2013.192
PURPOSE: Overexpression of cyclooxygenase 2 (COX-2) is thought to promote survival of transformed cells. Transforming growth factor beta (TGF-beta) exerts anti-proliferative effects on a broad range of epithelial cells. In...
Synergistic Effect of Sulindac and Simvastatin on Apoptosis in Lung Cancer A549 Cells through AKT-Dependent Downregulation of Survivin

Kim YS, Seol CH, Jung JW, Oh SJ, Hwang KE, Kim HJ, Jeong ET, Kim HR

  • Cancer Res Treat.
  • 2015 Jan;47(1):90-100.
  • doi: 10.4143/crt.2013.194
PURPOSE: Non-steroidal anti-inflammatory drugs (NSAIDs) and statins are potential chemopreventive or chemotherapeutic agents. The mechanism underlying the deregulation of survivin by NSAIDs and statins in human non-small cell lung cancer...
Identification of Hypoxanthine and Phosphoenolpyruvic Acid as Serum Markers of Chemoradiotherapy Response in Locally Advanced Rectal Cancer

Kim K, Yeo SG, Yoo BC

  • Cancer Res Treat.
  • 2015 Jan;47(1):78-89.
  • doi: 10.4143/crt.2013.127
PURPOSE: Patients show variable responses to chemoradiotherapy (CRT), which is generally administered before surgery for locally advanced rectal cancer (LARC). The aim of this study was to identify molecular markers...
Changes in the Mean Corpuscular Volume after Capecitabine Treatment Are Associated with Clinical Response and Survival in Patients with Advanced Gastric Cancer

Jung HA, Kim HJ, Maeng CH, Park SH, Lee J, Park JO, Park YS, Lim HY, Kang WK

  • Cancer Res Treat.
  • 2015 Jan;47(1):72-77.
  • doi: 10.4143/crt.2013.172
PURPOSE: Capecitabine is known to increase mean corpuscular volume (MCV). To define the incidence of capecitabine-induced macrocytosis and its association with chemotherapy outcomes, we investigated data of 89 patients with...
Metachronous Double Primary Cancer after Treatment of Breast Cancer

Kim JY, Song HS

  • Cancer Res Treat.
  • 2015 Jan;47(1):64-71.
  • doi: 10.4143/crt.2013.215
PURPOSE: The pattern of double primary cancer after treatment for breast cancer is important for patient survival. MATERIALS AND METHODS: We analyzed 108 cases of metachronous double primary cancer in breast...
Ovarian Ablation Using Goserelin Improves Survival of Premenopausal Patients with Stage II/III Hormone Receptor-Positive Breast Cancer without Chemotherapy-Induced Amenorrhea

Zhou J, Wu SG, Wang JJ, Sun JY, Li FY, Lin Q, Lin HX, He ZY

  • Cancer Res Treat.
  • 2015 Jan;47(1):55-63.
  • doi: 10.4143/crt.2013.165
PURPOSE: The purpose of this study was to assess the value of ovarian ablation using goserelin in premenopausal patients with stage II/III hormone receptor-positive breast cancer without chemotherapy-induced amenorrhea (CIA). MATERIALS...
Analysis of the Prognostic Factors for Distant Metastasis after Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Head and Neck Cancer

Kim DH, Kim WT, Lee JH, Ki YK, Nam JH, Lee BJ, Lee JC, Choi YJ, Seol YM, Kim DW

  • Cancer Res Treat.
  • 2015 Jan;47(1):46-54.
  • doi: 10.4143/crt.2013.212
PURPOSE: The aim of this study is to identify the prognostic factors of distant metastasis (DM) after induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CRT) for locoregionally advanced head and...
Phase I Dose-Escalation Study of Proton Beam Therapy for Inoperable Hepatocellular Carcinoma

Kim TH, Park JW, Kim YJ, Kim BH, Woo SM, Moon SH, Kim SS, Koh YH, Lee WJ, Park SJ, Kim JY, Kim DY, Kim CM

  • Cancer Res Treat.
  • 2015 Jan;47(1):34-45.
  • doi: 10.4143/crt.2013.218
PURPOSE: The purpose of this study is to determine the optimal dose of proton beam therapy (PBT) in hepatocellular carcinoma (HCC) patients. MATERIALS AND METHODS: Inoperable HCC patients who had naive,...
Prospective Evaluation of the Feasibility of Sentinel Lymph Node Biopsy in Breast Cancer Patients with Negative Axillary Conversion after Neoadjuvant Chemotherapy

Lee HD, Ahn SG, Lee SA, Lee HM, Jeong J

  • Cancer Res Treat.
  • 2015 Jan;47(1):26-33.
  • doi: 10.4143/crt.2013.208
PURPOSE: Tumor response to neoadjuvant chemotherapy (NAC) may adversely affect the identification and accuracy rate of sentinel lymph node biopsy (SLNB). This study was conducted to evaluate the feasibility of...
A Phase I/II Trial to Evaluate the Technical Feasibility of Partial Breast Irradiation with Three-Dimensional Conformal Radiation Therapy in Korean Women with Stage I Breast Carcinoma: An Initial Report of the Korean Radiation Therapy Oncology Group (KROG

Jeong JU, Yoon JH, Park MH, Yoon MS, Song JY, Nam TK, Chung WK, Kim YH, Suh CO, Ahn SJ

  • Cancer Res Treat.
  • 2015 Jan;47(1):18-25.
  • doi: 10.4143/crt.2013.202
PURPOSE: This prospective study was designed to verify the technical feasibility of partial breast irradiation in breast cancer patients with small breasts, which are commonly encountered in Korean women. MATERIALS AND...
Incidence and Survival of Pediatric Soft Tissue Sarcomas: Comparison between Adults and Children

Lim SM, Yoo CJ, Han JW, Cho YJ, Kim SH, Ahn JB, Rha SY, Shin SJ, Chung HC, Yang WI, Shin KH, Rho JK, Kim HS

  • Cancer Res Treat.
  • 2015 Jan;47(1):9-17.
  • doi: 10.4143/crt.2013.157
PURPOSE: Pediatric-type sarcomas such as rhabdomyosarcoma (RMS), Ewing sarcoma (EWS), primitive neuroectodermal tumor (PNET), and desmoplastic small round-cell tumor (DSRCT) are rare in adults, with limited studies on their prognosis...
Patient's Factors at Entering Hospice Affecting Length of Survival in a Hospice Center

Lee GJ, Ahn HS, Go SE, Kim JH, Seo MW, Kang SH, Yang YR, Lee MY, Lee KO, Chun SH, Jin JY

  • Cancer Res Treat.
  • 2015 Jan;47(1):1-8.
  • doi: 10.4143/crt.2013.148
PURPOSE: In order to provide effective hospice care, adequate length of survival (LOS) in hospice is necessary. However the reported average LOS is much shorter. Analysis of LOS in hospice...

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