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A Locally Advanced Breast Cancer with Difficult Differential Diagnosis of Carcinosarcoma and Atypical Medullary Carcinoma, which had Poor Response to Adriamycin- and Taxane-based Neoadjuvant Chemotherapy: A Case Report

Kim SH, Chung HC, Jeong J, Kim JH, Rha SY, Ahn JB, Cho NH, Jeung HC

  • Cancer Res Treat.
  • 2007 Sep;39(3):134-137.
Atypical medullary carcinomas and carcinosarcoma have unique histopathological features. Here we present a case with a breast malignancy that had pathological characteristics of both. A 54-year old patient with a...
Extraskeletal Mesenchymal Chondrosarcoma of the Heart Responded to Systemic Chemotherapy: A Case Report

Hsing CT, Oh SY, Lee S, Kwon HC, Kim SH, Park TH, Woo JS, Na SH, Kim HJ

  • Cancer Res Treat.
  • 2007 Sep;39(3):131-133.
Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm of an extraskeletal origin, and this predominately occurs in the head and neck, and also in the lower extremities. Fewer than twenty cases...
Activation of ATM-dependent DNA Damage Signal Pathway by a Histone Deacetylase Inhibitor, Trichostatin A

Lee JS

  • Cancer Res Treat.
  • 2007 Sep;39(3):125-130.
PURPOSE: Ataxia-telangiectasia mutated (ATM) kinase regulates diverse cellular DNA damage responses, including genome surveillance, cell growth, and gene expression. While the role of histone acetylation/deacetylation in gene expression is well...
Functional Link between DNA Damage Responses and Transcriptional Regulation by ATM in Response to a Histone Deacetylase Inhibitor TSA

Lee JS

  • Cancer Res Treat.
  • 2007 Sep;39(3):116-124.
PURPOSE: Mutations in the ATM (ataxia-telangiectasia mutated) gene, which encodes a 370 kd protein with a kinase catalytic domain, predisposes people to cancers, and these mutations are also linked to...
Glucose Transporter-1 Expression in Squamous Cell Carcinoma of the Tongue

Choi YS, Kim SJ, Kim DS, Park SJ, Park Y, Shin HJ, Jung KY, Baek SK, Shin BK, Choi JW, Kim BS, Shin SW, Kim YH, Kim JS

  • Cancer Res Treat.
  • 2007 Sep;39(3):109-115.
PURPOSE: Tumor cells are known to express hypoxia-related proteins such as glucose transporter-1 (Glut-1). These hypoxia-induced changes may allow tumor cells to survive under sustained hypoxic microenvironments, and the surviving...
Bone Metastasis from Primary Hepatocellular Carcinoma: Characteristics of Soft Tissue Formation

Kim S, Chun M, Wang H, Cho S, Oh YT, Kang SH, Yang J

  • Cancer Res Treat.
  • 2007 Sep;39(3):104-108.
PURPOSE: To assess the characteristics of bone metastasis from hepatocellular carcinoma and the radiation field arrangement based on imaging studies. MATERIALS AND METHODS: Fifty-three patients (84 lesions) with bone metastasis from...
Oxaliplatin, 5-FU, Folinic Acid as First-line Palliative Chemotherapy in Elderly Patients with Metastatic or Recurrent Gastric Cancer

Choi IS, Oh DY, Kim BS, Lee KW, Kim JH, Lee JS

  • Cancer Res Treat.
  • 2007 Sep;39(3):99-103.
PURPOSE: We investigated the efficacy and safety of a combination of oxaliplatin, 5-fluorouracil (5-FU), and folinic acid (FA) as first-line palliative chemotherapy for elderly patients with metastatic or recurrent gastric...
The Efficacy of an Induction Chemotherapy Combination with Docetaxel, Cisplatin, and 5-FU Followed by Concurrent Chemoradiotherapy in Advanced Head and Neck Cancer

Ahn JS, Cho SH, Kim OK, Lee JK, Yang DH, Kim YK, Lee JJ, Lim SC, Kim HJ, Chung WK, Chung IJ

  • Cancer Res Treat.
  • 2007 Sep;39(3):93-98.
PURPOSE: This study was performed to determine the feasibility and safety of the use of induction chemotherapy combined with docetaxel, cisplatin, and 5-fluorouracil (TPF) followed by concurrent chemoradiation therapy for...

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