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10 results

Three Cases of Synchronous Solid Tumor and Multiple Myeloma

Ji SH, Park JO, Lee J, Oh MJ, Lim DH, Park BB, Park KW, Lee SH, Kim K, Kim WS, Jung CW, Park YS, Im YH, Kang WK, Lee MH, Park K

  • Cancer Res Treat.
  • 2004 Oct;36(5):338-340.
The association between a multiple myeloma and a secondary solid tumor is not well established. Some reports showed an increased risk of secondary solid neoplasms in multiple myeloma patients, but...
Dexamethasone Inhibits TRAIL- and Anti-cancer Drugs-induced Cell Death in A549 Cells through Inducing NF-kappaB-independent cIAP2 Expression

Kim YS, Park JS, Jee YK, Lee KY

  • Cancer Res Treat.
  • 2004 Oct;36(5):330-337.
PURPOSE: We have examined that dexamethasone inhibits apoptotic cell death of A549 lung epithelial cells through TRAIL and anti-cancer drugs. The purpose of the study is to determine the roles...
Phenylacetate Induces Growth Inhibition and Apoptosis of Human Osteosarcoma Cells

Park JH, Park MY, Park HS, Jang KY, Chung MJ, Moon WS, Lee DG, Kang MJ

  • Cancer Res Treat.
  • 2004 Oct;36(5):324-329.
PURPOSE: Phenylacetate has potent antiproliferative effects in many malignant tumors. However, the exact mechanism as to how phenylacetate induces cell growth arrest remains unclear and very little is known about...
Activity of Green Tea Polyphenol Epigallocatechin-3-gallate Against Ovarian Carcinoma Cell Lines

Kim YW, Bae SM, Lee JM, Namkoong S, Han SJ, Lee BR, Lee IP, Kim SH, Lee YJ, Kim CK, Kim YW, Ahn WS

  • Cancer Res Treat.
  • 2004 Oct;36(5):315-323.
PURPOSE: A constituent of green tea, (-)-epigallocatechin-3-gallate (EGCG), is known to possess anti-cancer properties. In this study, the time-course of the anticancer effects of EGCG on human ovarian cancer cells...
Effective Inhibition of Cancer Cell Growth by a Novel Tripartite Transfection Complex Containing Ribbon Antisense Molecules to hTR

Park JG

  • Cancer Res Treat.
  • 2004 Oct;36(5):308-314.
PURPOSE: In the present study, ribbon antisense to the hTR RNA, a component of the telomerase complex, was employed to inhibit telomerase activity and cancer cell growth. MATERIALS AND METHODS:...
Expression of Caspase-3 and c-myc in Non-Small Cell Lung Cancer

Yoo JY, Kim CH, Song SH, Shim BY, Jeong YJ, Ahn MI, Kim S, Cho DG, Jo MS, Cho KD, Cho HJ, Kang SJ, Kim HK

  • Cancer Res Treat.
  • 2004 Oct;36(5):303-307.
PURPOSE: Caspase-3 is a cysteine protease that plays an important role in the process of apoptotic cell death, but little has been studied clinically on caspase-3 in lung cancer. Increased...
Prognostic Significance of CD24 Expression in Gastric Carcinoma

Darwish NS, Kim MA, Chang MS, Lee HS, Lee BL, Kim YI, Kim WH

  • Cancer Res Treat.
  • 2004 Oct;36(5):298-302.
PURPOSE: The human CD24 antigen is a small heavily glycosylated cell surface protein, which is expressed in hematological malignancies, as well as in a large variety of solid tumors. Its...
A Phase II Study of Weekly Paclitaxel, Cisplatin and Concurrent Radiation Therapy for Locally-Advanced Unresectable Non-Small Cell Lung Cancer: Early Closure due to Lack of Efficacy

Park SH, Kim MK, Kyung SY, Lim YH, An CH, Park JW, Jeong SH, Lee JW, Lee KC, Cho EK, Bang SM, Shin DB, Lee JH

  • Cancer Res Treat.
  • 2004 Oct;36(5):293-297.
PURPOSE: In this phase II study, the efficacy and safety of weekly paclitaxel concomitant with cisplatin and thoracic radiotherapy (TRT) was evaluated in patients with locally-advanced unresectable non-small cell lung...
A Phase II Trial of Docetaxel and Ifosfamide for Patients with Platinum-Resistant or Refractory Non-Small Cell Lung Cancer in a Salvage Setting

Lee GW, Kang JH, Kim SH, Lee HY, Kim HC, Lee WS, Lee JD, Hwang YS, Jang JS, Lee JS

  • Cancer Res Treat.
  • 2004 Oct;36(5):287-292.
PURPOSE: We conducted a phase II study of docetaxel and ifosfamide chemotherapy for patients with platinum- resistant or refractory non-small-cell lung cancer (NSCLC) to evaluate the response and toxicity profiles...
Transcription Factors in the Cellular Signaling Network as Prime Targets of Chemopreventive Phytochemicals

Surh YJ

  • Cancer Res Treat.
  • 2004 Oct;36(5):275-286.
Accumulating evidence from epidemiologic and laboratory studies support an inverse relationship between a regular consumption of fruits and vegetables and the risk of specific cancers. Numerous phytochemicals derived from edible...

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