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Site-Specific Mutagenesis in Escherichia coli by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives in Double-Stranded or Gapped Plasmids

Moon KY

  • Cancer Res Treat.
  • 2003 Feb;35(1):75-80.
PURPOSE: 7-Bromomethylbenz[alpha]anthracene is a known mutagen and carcinogen. The mutagenic potency of its two major DNA adducts, i.e., N2-(benz[alpha]anthracen-7-ylmethyl)-2'-deoxyguanosine (b[alpha]a2G) and N6-(benz[alpha]anthracen-7-ylmethyl)-2'-deoxyadenosine (b[alpha]a6A), as well as the simpler benzylated analogs,...
Clinical Experience in Conformal Stereotactic Radiotherapy of Irregularly Shaped Intracranial Tumors

Kim KH, Cho MJ, Kim DW, Kim JS, Kim SH, Song CJ, Song SH, Jang JY, Kim JS

  • Cancer Res Treat.
  • 2003 Feb;35(1):69-74.
PURPOSE: The dosimetric advantages of multiple non-coplanar stationary fields for stereotactic radiotherapy or adiosurgery (SRT/S) are well known. However, this technique is not widely used due to the logistical problems...
The Efficacy and Safety of DA-3030 (Recombinant Human Granulocyte Colony-Stimulating Factor) in Neutropenia after the Remission Induction Chemotherapy in Patients with Acute Myelogenous Leukemia

Min YJ, Suh CW, Park KU, Yoon SS, Park CH, Lee HG

  • Cancer Res Treat.
  • 2003 Feb;35(1):66-68.
PURPOSE: This study was conducted to determine the efficacy and safety of DA-3030 (a recombinant methionyl human granulocyte colony-stimulating factor, rhG-CSF), after remission induction chemotherapy, in patients with acute myelogenous...
Correlation between Retinoic Acid Sensitivity and IGFBP-3, AFP Protein Expression in Hepatoma Cell Lines

Jung HY, Lee YM, Yoo YD, Kim JS, Park SH, Kim YH

  • Cancer Res Treat.
  • 2003 Feb;35(1):59-65.
PURPOSE: Retinoic acid (RA) has been known to inhibit the proliferation, and to induce apoptosis, of various cancer cell lines. We investigated the correlation between the protein levels of the...
The Effect of More Aggressive Surgery in Esophageal Cancer

Park JK, Choi IB

  • Cancer Res Treat.
  • 2003 Feb;35(1):52-58.
PURPOSE: One of the most controversial aspects of surgery for esophageal cancer is the appropriate extent of lymphadenectomy to achieve the best outcome. The purpose of this study was to...
The Estimation of Breast Cancer Disease-Probability by Difference of Individual Susceptibility

Park SK, Yoo KY, Kang DH, Ahn SH, Noh DY, Choe KJ

  • Cancer Res Treat.
  • 2003 Feb;35(1):35-51.
PURPOSE: The aims were to evaluate the main risk factors (RFs) of breast cancer and to estimate the individual disease-probability from combinations of RFs in Korean female. MATERIALS AND METHODS:...
A Multi-Center, Phase II Clinical Trial of Genexol(R) (Paclitaxel) and Cisplatin for Patients with Non-Small Cell Lung Cancer

Lee SH, Park K, Suh C, Kim HK, Kim JS, Im YH, Kim SW, Heo DS, Bang YJ, Kim NK

  • Cancer Res Treat.
  • 2003 Feb;35(1):30-34.
PURPOSE: A combination of paclitaxel and cisplatin is an effective and safe regimen for advanced non-small cell lung cancer (NSCLC). We conducted a multi-center, phase II trial to evaluate the...
Phase I and Pharmacokinetic Study of Intraoperative Intraperitoneal Heptaplatin in Patients with Surgically Resected Advanced Gastric Cancer

Yu W, Chung HY, Park SH, Cho YB, Lim YS

  • Cancer Res Treat.
  • 2003 Feb;35(1):25-29.
PURPOSE: Heptaplatin, a new platinum analog, has favorable toxicity profiles and antitumor activity, comparable to those of cisplatin, in the treatment of gastric cancer. This study was designed to define...
RImmunohistochemical Evaluation of E-cadherin/catenin (alpha-, beta-, gamma-catenin and p120CTN) Complex Expression in Early Gastric Cancer

Jo TY, Jeon TY, Chae KH, Kim DH, Sim MS, Park DY, Suh KS

  • Cancer Res Treat.
  • 2003 Feb;35(1):16-24.
PURPOSE: The significance of abnormal E-cadherin/ catenin complex expression and the correlation of each of its components in cancer remain unclear. This study aimed to characterize the clinical significance of...
Overexpression of c-met Protein in Gastric Cancer and Role of uPAR as a Therapeutic Target

Oh HA, Lee G, Kang HJ, Kim YG, Bae SH, Lee JL, Lee KH, Hyun MS, Kim DS

  • Cancer Res Treat.
  • 2003 Feb;35(1):9-15.
PURPOSE: One of the members of the tyrosine kinase receptor family is the protein product of the c-met proto-oncogene, which is the receptor for hepatocyte growth factor (HGF). HGF is...
The Serum Assay of Soluble CD44 Standard, CD44 Variant 5, and CD44 Variant 6 in Patients with Gastric Cancer

Yoo CH, Noh SH

  • Cancer Res Treat.
  • 2003 Feb;35(1):3-8.
PURPOSE: Alternative splicing of CD44 and aberrant levels of soluble CD44 (sCD44) protein in the serum of cancer patients has been correlated to tumor progression and metastasis. The purpose of...
Molecular Markers in Gastric Cancer: Can They Predict Prognosis?

Kim SJ, Kim YH

  • Cancer Res Treat.
  • 2003 Feb;35(1):1-2.
No abstract available.

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