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HER-2/neu in Breast Cancer: Is Consensus Reached in Standard Testing?

Lee SS

  • KMID: 2166195
  • Cancer Res Treat.
  • 2003 Apr;35(2):87-89.
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Passive Smoking and Lung Cancer

Bin H, Lee JS

  • KMID: 2166196
  • Cancer Res Treat.
  • 2003 Apr;35(2):90-95.
Passive smoking is an important risk factor for lung cancer and its impact might be more significant than generally appreciated in Korea. We reviewed the literatures that support the biologic...
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M llerian-Type Gland Inclusions in Pelvic Lymph Nodes Mimicking Metastasis: A Case Report and Review of the Literature

Yoo J, Choi HJ, Kang SJ

  • KMID: 2166208
  • Cancer Res Treat.
  • 2003 Apr;35(2):165-167.
Benign lymph node inclusions are rare, and can be mistaken for metastasis. We report, herein, a case of a 50-year-old woman who underwent a hysterectomy, with a lymphadenectomy, for an...
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A Small Cell Lung Cancer Concurrently Diagnosed with Paraneoplastic Dermatomyositis

Lee HS, Zang DY, Seo YI, Kim DG, Kim EJ, Ahn JS, Park HR

  • KMID: 2166207
  • Cancer Res Treat.
  • 2003 Apr;35(2):161-164.
Dermatomyositis is an inflammatory myopathy, of unknown etiology, which is characterized by cutaneous rashes, accompanied by progressive and symmetric proximal muscle weakness. Especially in older people, the incidences of malignant...
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Evaluation of Her-2/neu in Breast Cancer: Comparison of Immunohistochemistry and Polymerase Chain Reaction

Lee MJ, Jeon HJ

  • KMID: 2166197
  • Cancer Res Treat.
  • 2003 Apr;35(2):96-101.
PURPOSE: In breast cancer, Her-2/neu amplification/overexpression predicts a poor clinical outcome, and enhanced survival benefits have been reported with Her-2/neu targeted therapy. Currently, there are several methods for assessing the...
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Prognosis of Malignant Obstructive Jaundice Following Surgery for Gastric Carcinoma

Song JH, Yoon KY, Lee SH

  • KMID: 2166202
  • Cancer Res Treat.
  • 2003 Apr;35(2):130-134.
PURPOSE: Obstructive jaundice is a rare presentation, but is an ominous prognostic sign in patients undergoing surgery for a gastric carcinoma. Therefore, we investigated the prognosis of malignant obstructive jaundice...
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Irinotecan Combined with Bolus Fluorouracil, Continuous Infusion Fluorouracil, and Low-Dose Leucovorin Every Two Weeks in Patients with Oxaliplatin Pretreated Metastatic Colorectal Cancer

Kwon HC, Kim SH, Kim JS, Kim HJ

  • KMID: 2166203
  • Cancer Res Treat.
  • 2003 Apr;35(2):135-140.
PURPOSE: To determine the efficacy and tolerance of irinotecan in combination with fluorouracil (5-FU) plus leucovorin (LV) in patients whose disease has progressed after treatment with an oxaliplatin-based therapy. MATERIALS...
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Infusional 5-Fluorouracil, Leucovorin and Docetaxel in Advanced Gastric Cancer

Kim YT, Sohn JH, Kim SH, Rha SY, Kim C, Roh JK, Kim BS, Jang WI, Chung HC

  • KMID: 2166201
  • Cancer Res Treat.
  • 2003 Apr;35(2):123-129.
PURPOSE: This study was performed to estimate the response rate and toxicity of a combination chemotherapy, which included infusional 5-Fluorouracil, Leucovorin and Docetaxel in the treatment of patients with an...
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The Prognostic Significance of the Overexpression of HER-2/ neu in Korean Gastric Carcinomas and the In Vitro Effects of Anti-HER-2/neu Antibody on Cell Growth in the Gastric Carcinoma Cell Lines

Im SA, Lee KE, Nam E, Nam SH, Kim DY, Seong CM, Park HY, Han WS, Seoh JY, Lee SN

  • KMID: 2166199
  • Cancer Res Treat.
  • 2003 Apr;35(2):109-116.
PURPOSE: The HER2 gene encodes a 185-kd transmembrane glycoprotein receptor (p185(HER2)) that has partial homology with the epidermal growth factor receptor (EGFR) and shares intrinsic tyrosine kinase activity. The HER2...
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A Clinical Analysis of PTEN Expressions in Breast Cancers

Cho HJ, Kim JS, Kim KH, Ahn CH, Park WC, Oh SJ, Jung SS, Lim KW, Im SA

  • KMID: 2166198
  • Cancer Res Treat.
  • 2003 Apr;35(2):102-108.
PURPOSE: The PTEN gene, a novel tumor suppressor, is localized to chromosome 10q23.3 and shares extensive homology with the cytoskeletal protein, tensin. A high frequency of mutations at the PTEN...
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Gene Expression Profiling of Non-Small Cell Lung Cancer

Roh MS, Kwon HC, Jeong JS, Kim DC, Son CH, Lee SK, Choi PJ, Lee JI, Lee KN, Kim HJ, Yoon JH, Hwang TH

  • KMID: 2166206
  • Cancer Res Treat.
  • 2003 Apr;35(2):154-160.
PURPOSE: cDNA microarray provided a powerful alternative, with an unprecedented view scope, in monitoring gene expression levels, and led to the discovery of regulatory pathways involved in complicated biological processes....
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Differential Sensitivity of Taxol-induced Apoptosis in U2OS and SaOS2 Osteogenic Sarcoma Cells

Kim JH, Chin BR, Kim SY, Kim JR, Baek SH

  • KMID: 2166205
  • Cancer Res Treat.
  • 2003 Apr;35(2):148-153.
PURPOSE: Taxol (Paclitaxel) is a new generation of chemotherapeutic drug proven to be effective in the treatment of many cancers. In this study, to further demonstrate the differential effect of...
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Patterns of Failure and Prognostic Factors in Anal Cancer Treated with Radiotherapy

Kim KJ, Kim JH, Choi EK, Ahn SD, Lee SW, Kim JC, Yu CS, Kim HC, Lee JH, Kim TW

  • KMID: 2166204
  • Cancer Res Treat.
  • 2003 Apr;35(2):141-147.
PURPOSE: To analyze the patterns of failure and prognostic factors affecting the local control and survivals in anal cancer treated with definitive radiotherapy, and to find the most effective treatment...
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Pilot Study of Heptaplatin, UFT-E and Leucovorin in Advanced Gastric Carcinoma

Oh SC, Yoon SY, Seo JH, Choi CW, Kim BS, Shin SW, Kim YH, Kim SY, Yoon HJ, Cho KS, Kim JS

  • KMID: 2166200
  • Cancer Res Treat.
  • 2003 Apr;35(2):117-122.
PURPOSE: Heptaplatin (SKI-2053R, Sunpla ), a new platinum analogue which has a better toxicity profile than cisplatin, has been used with 5-fluorouracil (5-FU) continuous infusion for the treatment of advanced...
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