- Bilateral Breast Metastases from Epstein-Barr Virus-Associated Gastric Cancer during Pregnancy: Is There a Method to Its Madness?
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Quaquarini E, Vanoli A, Frascaroli M, Viglio A, Lucioni M, Presti D, Lobascio G, Pietrabissa A, Bernardo A, Paulli M
- KMID: 2471930
- J Gastric Cancer.
- 2020 Mar;20(1):106-114.
- doi: 10.5230/jgc.2020.20.e1
Breast metastases of extramammary malignant neoplasms are rare, with an incidence of 0.3%–2.7% among all malignant mammary tumors. Breast metastases from gastric carcinoma are very rare ( -
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- Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1
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Deng Y, Guo W, Li G, Li S, Li H, Li X, Niu B, Song M, Zhang Y, Xu Z, Li F
- KMID: 2470879
- J Breast Cancer.
- 2020 Feb;23(1):20-35.
- doi: 10.4048/jbc.2020.23.e7
PURPOSE: C-terminal binding protein 1 (CtBP1) is a transcriptional co-repressor that is overexpressed in many cancers. CtBP1 transcriptionally represses a broad array of tumor suppressors, which promotes cancer cell proliferation,... -
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- Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells
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Kang SH, Kim SW, Kim KJ, Cho KH, Park JW, Kim CD, Do JY
- KMID: 2469377
- Kidney Res Clin Pract.
- 2019 Dec;38(4):472-480.
- doi: 10.23876/j.krcp.19.049
BACKGROUND: We investigated the effects of tranilast on epithelial-to-mesenchymal transition (EMT) in an animal model and on the EMT signaling pathway in human peritoneal mesothelial cells (HPMCs). METHODS: We performed in... -
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- p90RSK Activation Promotes Epithelial-Mesenchymal Transition in Cisplatin-Treated Triple-Negative Breast Cancer Cells
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Jin Y, Heo KS
- KMID: 2468028
- J Bacteriol Virol.
- 2019 Dec;49(4):221-229.
- doi: 10.4167/jbv.2019.49.4.221
p90 ribosomal S6 kinase (p90RSK), one of the downstream effectors in ERK1/2 pathways, shows high expression in human breast cancer tissues. However, its role in breast cancer development and drug... -
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- G0/G1 Switch 2 Induces Cell Survival and Metastasis through Integrin-Mediated Signal Transduction in Human Invasive Breast Cancer Cells
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Cho E, Kwon YJ, Ye DJ, Baek HS, Kwon TU, Choi HK, Chun YJ
- KMID: 2462887
- Biomol Ther.
- 2019 Nov;27(6):591-602.
- doi: 10.4062/biomolther.2019.063
Human breast cancer cell line, MDA-MB-231, is highly invasive and aggressive, compared to less invasive cell line, MCF-7. To explore the genes that might influence the malignancy of MDA-MB-231, DNA... -
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- Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells
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Zhu SM, Park YR, Seo SY, Kim IH, Lee ST, Kim SW
- KMID: 2465818
- Intest Res.
- 2019 Oct;17(4):527-536.
- doi: 10.5217/ir.2019.00031
BACKGROUND/AIMS: Transforming growth factor-β1 (TGF-β1) induction of epithelial-mesenchymal transition (EMT) is one of the mechanisms by which colorectal cancer (CRC) cells acquire migratory and invasive capacities, and subsequently metastasize. Parthenolide... -
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- Vitamin D maintains E-cadherin intercellular junctions by downregulating MMP-9 production in human gingival keratinocytes treated by TNF-α
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Oh C, Kim HJ, Kim HM
- KMID: 2461018
- J Periodontal Implant Sci.
- 2019 Oct;49(5):270-286.
- doi: 10.5051/jpis.2019.49.5.270
PURPOSE: Despite the well-known anti-inflammatory effects of vitamin D in periodontal health, its mechanism has not been fully elucidated. In the present study, the effect of vitamin D on strengthening... -
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- MiR-1246 Promotes Metastasis and Invasion of A549 cells by Targeting GSK-3β‒Mediated Wnt/β-Catenin Pathway
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Yang F, Xiong H, Duan L, Li Q, Li X, Zhou Y
- KMID: 2460591
- Cancer Res Treat.
- 2019 Oct;51(4):1420-1429.
- doi: 10.4143/crt.2018.638
PURPOSE: MicroRNAs (miRNAs) are a group of small non-coding RNAs involved in different cancers, including lung cancer. Here, we aim to investigate the expression profiles of circulating miRNAs and their... -
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- Immunohistochemical Study of Fas/Fas-ligand and Cadherin Expression in Basal Cell Carcinoma in Sun-Exposed and Sun-Protected Areas
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Kim JH, Suh HS, Choi YS
- KMID: 2465949
- Korean J Dermatol.
- 2019 Sep;57(8):425-432.
BACKGROUND: UV radiation is the most important risk factor in the development of basal cell carcinoma (BCC). However, the association between tumorigenesis and the progression of BCC and UV exposure... -
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- Immunohistochemical Expression of Epithelial-Mesenchymal Transition Markers in Early Gastric Cancer: Cancer Tissue versus Noncancer Tissue
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Jung HJ, Hong SJ, Kim SH
- KMID: 2464668
- Clin Endosc.
- 2019 Sep;52(5):464-471.
- doi: 10.5946/ce.2018.181
BACKGROUND/AIMS: Epithelial-mesenchymal transition (EMT) is a developmental process, wherein the epithelial cells show reduced intercellular adhesions and acquire migratory fibroblastic properties. EMT is associated with downregulation in epithelial marker expression,... -
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- KIF11 Functions as an Oncogene and Is Associated with Poor Outcomes from Breast Cancer
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Zhou J, Chen WR, Yang LC, Wang J, Sun JY, Zhang WW, He ZY, Wu SG
- KMID: 2454312
- Cancer Res Treat.
- 2019 Jul;51(3):1207-1221.
- doi: 10.4143/crt.2018.460
PURPOSE: The study aimed to search and identify genes that were differentially expressed in breast cancer, and their roles in cancer growth and progression. MATERIALS AND METHODS: The Gene Expression Omnibus... -
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- Changes in oncogenic protein levels in peri-implant oral malignancy: a case report
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Seo MH, Myoung H, Lee JH, Kim SM, Lee SK
- KMID: 2468993
- Maxillofac Plast Reconstr Surg.
- 2019 ;41(1):46.
- doi: 10.1186/s40902-019-0235-z
BACKGROUND: Oral squamous cell carcinoma (OSCC) constitutes a group of tumors that exhibit heterogeneous biology, histopathology, and clinical behaviors. CASE PRESENTATION: A 73-year-old male had a whitish leukoplakia-like lesion around inflamed... -
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- NFATC3–PLA2G15 Fusion Transcript Identified by RNA Sequencing Promotes Tumor Invasion and Proliferation in Colorectal Cancer Cell Lines
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Jang JE, Kim HP, Han SW, Jang H, Lee SH, Song SH, Bang D, Kim TY
- KMID: 2437629
- Cancer Res Treat.
- 2019 Jan;51(1):391-401.
- doi: 10.4143/crt.2018.103
PURPOSE: This study was designed to identify novel fusion transcripts (FTs) and their functional significance in colorectal cancer (CRC) lines. MATERIALS AND METHODS: We performed paired-end RNA sequencing of 28 CRC... -
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- Lobular Breast Carcinoma Metastasis to the Thyroid Gland: Case Report and Literature Review
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Bourcier K, Fermeaux V, Leobon S, Deluche E
- KMID: 2429826
- J Breast Cancer.
- 2018 Dec;21(4):463-467.
- doi: 10.4048/jbc.2018.21.e55
Metastasis from primary cancer to the thyroid is uncommon in breast cancer. Here we present a case of lobular breast carcinoma that metastasized to the thyroid. A 54-year-old woman without... -
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- Gland Attenuation, a Novel Morphological Feature of Colorectal Cancer: Evidence for an Epithelial-Mesenchymal Transition
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Baek TH, Kang DW, Kim JH, Son HJ
- KMID: 2422081
- Ann Coloproctol.
- 2018 Aug;34(4):187-196.
- doi: 10.3393/ac.2017.12.02
PURPOSE: Along the invasive margin, colorectal cancer may show distinctive morphologic changes characterized by an asymmetrically attenuating tumor gland with loss of polarity. The author coined the term ‘gland attenuation... -
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- Role of E-cadherin and cyclin D1 as predictive markers of aggression and clonal expansion in head and neck squamous cell carcinoma
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Shergill K, Sen A, Pillai HJ
- KMID: 2419234
- J Korean Assoc Oral Maxillofac Surg.
- 2018 Aug;44(4):182-190.
- doi: 10.5125/jkaoms.2018.44.4.182
OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Inconsistency in various histopathologic features for predicting nodal metastasis and overall prognosis and a better... -
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- MicroRNA-373 Inhibits Cell Proliferation and Invasion via Targeting BRF2 in Human Non-small Cell Lung Cancer A549 Cell Line
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Wang L, Qu J, Zhou L, Liao F, Wang J
- KMID: 2417882
- Cancer Res Treat.
- 2018 Jul;50(3):936-949.
- doi: 10.4143/crt.2017.302
PURPOSE: The purpose of this study was to investigate the biological role and mechanism of miR-373 targeting of TFIIB-related factor 2 (BRF2) in the regulation of non-small cell lung cancer... -
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- Effects of aristolochic acid I and/or hypokalemia on tubular damage in C57BL/6 rat with aristolochic acid nephropathy
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Yi JH, Han SW, Kim WY, Kim J, Park MH
- KMID: 2416003
- Korean J Intern Med.
- 2018 Jul;33(4):763-773.
- doi: 10.3904/kjim.2016.097
BACKGROUND/AIMS: This study was designed to investigate the roles of aristolochic acid I (AA-I) and hypokalemia in acute aristolochic acid nephropathy (AAN). METHODS: After an adaptation period (1 week), a total... -
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- Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells
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Zhang X, Shi D, Liu YP, Chen WJ, Wu D
- KMID: 2412654
- Yonsei Med J.
- 2018 Jul;59(5):633-642.
- doi: 10.3349/ymj.2018.59.5.633
PURPOSE: To investigate the effects of Helicobacter pylori (H. pylori)-CagA and the urease metabolite NH₄⺠on mucin expression in AGS cells. MATERIALS AND METHODS: AGS cells were transfected with CagA and/or... -
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- Luteolin Induces Apoptosis via Mitochondrial Pathway and Inhibits Invasion and Migration of Oral Squamous Cell Carcinoma by Suppressing Epithelial-Mesenchymal Transition Induced Transcription Factors
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Park BS, Kil JJ, Kang HM, Yu SB, Park DB, Park JA, Kim IR
- KMID: 2437357
- Int J Oral Biol.
- 2018 Jun;43(2):69-76.
- doi: 10.11620/IJOB.2018.43.2.069
Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy. Numerous therapies have been proposed for its cure. Research is continually being conducted to develop new forms... -
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