- Proteomic Signatures in Spermatozoa Reveal the Role of Paternal Factors in Recurrent Pregnancy Loss
-
Mohanty G, Jena SR, Nayak J, Kar S, Samanta L
- KMID: 2465415
- World J Mens Health.
- 2020 Jan;38(1):103-114.
- doi: 10.5534/wjmh.190034
PURPOSE: To identify the paternal factors responsible for aberrant embryo development leading to loss of foetus in recurrent pregnancy loss (RPL) through proteomic analysis of ejaculated spermatozoa. MATERIALS AND METHODS: This... -
- CITED
-
- Close
- SHARE
-
- Close
- Anti-inflammatory Activity of Sambucus Plant Bioactive Compounds against TNF-α and TRAIL as Solution to Overcome Inflammation Associated Diseases: The Insight from Bioinformatics Study
-
Putra WE, Ode Salma , Rifa'i M
- KMID: 2459962
- Nat Prod Sci.
- 2019 Sep;25(3):215-221.
- doi: 10.20307/nps.2019.25.3.215
Inflammation is the crucial biological process of immune system which acts as body's defense and protective response against the injuries or infection. However, the systemic inflammation devotes the adverse effects... -
- CITED
-
- Close
- SHARE
-
- Close
- Analysis of vitamin D-binding protein (VDBP) gene polymorphisms in Korean women with and without endometriosis
-
Cho MC, Kim JH, Jung MH, Cho IA, Jo HC, Shin JK, Lee SA, Choi WJ, Lee JH
- KMID: 2458501
- Clin Exp Reprod Med.
- 2019 Sep;46(3):132-139.
- doi: 10.5653/cerm.2019.00122
OBJECTIVE: Vitamin D-binding protein (VDBP) mediates various biological processes in humans. The goal of this study was to investigate whether VDBP gene polymorphisms could predispose Korean women to endometriosis. METHODS: We... -
- CITED
-
- Close
- SHARE
-
- Close
- Enhanced Anti-Cancer Effects of Conditioned Medium from Hypoxic Human Umbilical Cord–Derived Mesenchymal Stem Cells
-
Han KH, Kim AK, Jeong GJ, Jeon HR, Bhang SH, Kim DI
- KMID: 2465899
- Int J Stem Cells.
- 2019 Jul;12(2):291-303.
- doi: 10.15283/ijsc19002
BACKGROUND AND OBJECTIVES: There have been contradictory reports on the pro-cancer or anti-cancer effects of mesenchymal stem cells. In this study, we investigated whether conditioned medium (CM) from hypoxic human... -
- CITED
-
- Close
- SHARE
-
- Close
- miR-148b-3p, miR-190b, and miR-429 Regulate Cell Progression and Act as Potential Biomarkers for Breast Cancer
-
Dai W, He J, Zheng L, Bi M, Hu F, Chen M, Niu H, Yang J, Luo Y, Tang W, Sheng M
- KMID: 2450117
- J Breast Cancer.
- 2019 Jun;22(2):219-236.
- doi: 10.4048/jbc.2019.22.e19
PURPOSE: Breast cancer is the most frequently diagnosed malignancy in women worldwide. MicroRNAs (miRNAs) are thought to serve as potential biomarkers in various cancers, including breast cancer. METHODS: We evaluated the... -
- CITED
-
- Close
- SHARE
-
- Close
- Mechanistic Target of Rapamycin Pathway in Epileptic Disorders
-
Kim JK, Lee JH
- KMID: 2453232
- J Korean Neurosurg Soc.
- 2019 May;62(3):272-287.
- doi: 10.3340/jkns.2019.0027
The mechanistic target of rapamycin (mTOR) pathway coordinates the metabolic activity of eukaryotic cells through environmental signals, including nutrients, energy, growth factors, and oxygen. In the nervous system, the mTOR... -
- CITED
-
- Close
- SHARE
-
- Close
- Differential Gene Expression Common to Acquired and Intrinsic Resistance to BRAF Inhibitor Revealed by RNA-Seq Analysis
-
Ahn JH, Hwang SH, Cho HS, Lee M
- KMID: 2447857
- Biomol Ther.
- 2019 May;27(3):302-310.
- doi: 10.4062/biomolther.2018.133
Melanoma cells have been shown to respond to BRAF inhibitors; however, intrinsic and acquired resistance limits their clinical application. In this study, we performed RNA-Seq analysis with BRAF inhibitor-sensitive (A375P)... -
- CITED
-
- Close
- SHARE
-
- Close
- Farnesylation-defective Rheb Increases Axonal Length Independently of mTORC1 Activity in Embryonic Primary Neurons
-
Choi S, Sadra A, Kang J, Ryu JR, Kim JH, Sun W, Huh SO
- KMID: 2450212
- Exp Neurobiol.
- 2019 Apr;28(2):172-182.
- doi: 10.5607/en.2019.28.2.172
Rheb (Ras homolog enriched in the brain) is a small GTPase protein that plays an important role in cell signaling for development of the neocortex through modulation of mTORC1 (mammalian-target-of-rapamycin-complex-1)... -
- CITED
-
- Close
- SHARE
-
- Close
- Regulation Mechanism of Long Noncoding RNAs in Colon Cancer Development and Progression
-
Tang X, Qiao X, Chen C, Liu Y, Zhu J, Liu J
- KMID: 2450186
- Yonsei Med J.
- 2019 Apr;60(4):319-325.
- doi: 10.3349/ymj.2019.60.4.319
Colorectal cancer (CRC) is the second most common cause of cancer-related death worldwide, and its high rates of relapse and metastasis are associated with a poor prognosis. Despite extensive research,... -
- CITED
-
- Close
- SHARE
-
- Close
- Perspective in Nuclear Theranostics Using Exosome for the Brain
-
Hwang DW
- KMID: 2448098
- Nucl Med Mol Imaging.
- 2019 Apr;53(2):108-114.
- doi: 10.1007//s13139-018-00567-6
Owing to its highly biocompatible property as naturally produced nanoscale particle and drug carrying ability, exosome has attracted much interest in the biomedical area. Versatile functions of exosome in biological... -
- CITED
-
- Close
- SHARE
-
- Close
- Diagnostic Significance of pH-Responsive Gd³âº-Based Tâ‚ MR Contrast Agents
-
Bhuniya S, Hong KS
- KMID: 2442229
- Investig Magn Reson Imaging.
- 2019 Mar;23(1):17-25.
- doi: 10.13104/imri.2019.23.1.17
We discuss recent advances in Gd-based Tâ‚-weighted MR contrast agents for the mapping of cellular pH. The pH plays a critical role in various biological processes. During the past two... -
- CITED
-
- Close
- SHARE
-
- Close
- Prediction of itching diagnostic marker through RNA sequencing of contact hypersensitivity and skin scratching stimulation mice models
-
Kim YW, Zhou T, Ko EA, Kim S, Lee D, Seo Y, Kwon N, Choi T, Lim H, Cho S, Bae G, Hwang Y, Kim D, Park H, Lee M, Jang E, Choi J, Bae H, Lim I, Bang H, Ko JH
- KMID: 2438089
- Korean J Physiol Pharmacol.
- 2019 Mar;23(2):151-159.
- doi: 10.4196/kjpp.2019.23.2.151
Pruritus (itching) is classically defined as an unpleasant cutaneous sensation that leads to scratching behavior. Although the scientific criteria of classification for pruritic diseases are not clear, it can be... -
- CITED
-
- Close
- SHARE
-
- Close
- Dysfunctional Mitochondrial Bioenergetics and Synaptic Degeneration in Alzheimer Disease
-
Tang J, Oliveros A, Jang MH
- KMID: 2448802
- Int Neurourol J.
- 2019 Feb;23(Suppl 1):S5-S10.
- doi: 10.5213/inj.1938036.018
Synapses are sites of high energy demand which are dependent on high levels of mitochondrial derived adenosine triphosphate. Mitochondria within synaptic structures are key for maintenance of functional neurotransmission and... -
- CITED
-
- Close
- SHARE
-
- Close
- MS-5, a Naphthalene Derivative, Induces the Apoptosis of an Ovarian Cancer Cell CAOV-3 by Interfering with the Reactive Oxygen Species Generation
-
Ma E, Jeong SJ, Choi JS, Nguyen TH, Jeong CH, Joo SH
- KMID: 2432066
- Biomol Ther.
- 2019 Jan;27(1):48-53.
- doi: 10.4062/biomolther.2018.020
Reactive oxygen species (ROS) are widely generated in biological processes such as normal metabolism and response to xenobiotic exposure. While ROS can be beneficial or harmful to cells and tissues,... -
- CITED
-
- Close
- SHARE
-
- Close
- Association of MicroRNA Polymorphisms With Hepatocellular Carcinoma in an Iranian Population
-
Farokhizadeh Z, Dehbidi S, Geramizadeh B, Yaghobi R, Malekhosseini SA, Behmanesh , Sanati MH, Afshari A, Moravej A, Karimi MH
- KMID: 2420272
- Ann Lab Med.
- 2019 Jan;39(1):58-66.
- doi: 10.3343/alm.2019.39.1.58
BACKGROUND: Single nucleotide polymorphisms (SNPs) can modulate various biological processes by influencing microRNA (miRNA) biogenesis and altering target selection. Common SNPs may alter the processing of miRNA and may be... -
- CITED
-
- Close
- SHARE
-
- Close
- Crosstalk between FXR and TGR5 controls glucagon-like peptide 1 secretion to maintain glycemic homeostasis
-
Kim H, Fang S
- KMID: 2459289
- Lab Anim Res.
- 2018 Dec;34(4):140-146.
- doi: 10.5625/lar.2018.34.4.140
Though bile acids have been well known as digestive juice, recent studies have demonstrated that bile acids bind to their endogenous receptors, including Farnesoid X receptor (FXR) and G protein-coupled... -
- CITED
-
- Close
- SHARE
-
- Close
- Roles of Oncogenic Long Non-coding RNAs in Cancer Development
-
Do H, Kim W
- KMID: 2439208
- Genomics Inform.
- 2018 Dec;16(4):e18.
- doi: 10.5808/GI.2018.16.4.e18
Long non-coding RNAs (lncRNAs) are classified as RNAs that are longer than 200 nucleotides and cannot be translated into protein. Several studies have demonstrated that lncRNAs are directly or indirectly... -
- CITED
-
- Close
- SHARE
-
- Close
- Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective
-
Chatterjee N, Gim J, Choi J
- KMID: 2434040
- Environ Health Toxicol.
- 2018 Sep;33(3):e2018015.
- doi: 10.5620/eht.e2018015
Epigenetics, potentially heritable changes in genome function that occur without alterations to DNA sequence, is an important but understudied component of ecotoxicology studies. A wide spectrum of environmental challenge, such... -
- CITED
-
- Close
- SHARE
-
- Close
- Single Molecule Method for Molecular Biology
-
Kim JH, Jeong C
- KMID: 2437355
- Int J Oral Biol.
- 2018 Jun;43(2):53-59.
- doi: 10.11620/IJOB.2018.43.2.053
In order to understand biological phenomena accurately, single molecule techniques using a physical research approach to molecular interactions have been developed, and are now widely being used to study complex... -
- CITED
-
- Close
- SHARE
-
- Close
- Translational Application of Single-cell Transcriptomic Analysis in Hepatocellular Carcinoma
-
Yoon SK
- KMID: 2409642
- J Liver Cancer.
- 2018 Mar;18(1):1-8.
- doi: 10.17998/jlc.18.1.1
The emergence of single-cell technology in recent years has made remarkable progress for understanding of biological process in various diseases including cancers. In particular of cancer, single-cell transcriptome analysis provides... -
- CITED
-
- Close
- SHARE
-
- Close
