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Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance

Lee JH, Jo KW, Shim TS

BACKGROUND: The purpose of this study was to analyze the relationship between the gene mutation patterns by the GenoType MTBDRplus (MTBDRplus) assay and the phenotypic drug susceptibility test (pDST) results...
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Acute toxicity of copper hydroxide and glyphosate mixture in Clarias gariepinus: interaction and prediction using mixture assessment models

Kingsley K

The study aimed to assess the single and joint lethal toxicity, type of interaction and the extent to which simple mathematical model of concentration addition (CA), independent action (IA) and...
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Validation of a Multiplexed Opsonophagocytic Assay for 11 Additional Pneumococcal Serotypes and Its Application to Functional Antibody Evaluation Induced by Pneumococcal Polysaccharide Vaccine

Cha J, Kim HW, Lee JH, Lee S, Kim KH

BACKGROUND: Various pneumococcal vaccines have been evaluated for immunogenicity by opsonophagocytic assay (OPA). A multiplexed OPA (MOPA) for 13 pneumococcal serotypes was developed by Nahm and Burton, and expanded to...
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Detection of Rifampicin- and Isoniazid-Resistant Mycobacterium tuberculosis Using the Quantamatrix Multiplexed Assay Platform System

Wang HY, Uh Y, Kim S, Cho E, Lee JS, Lee H

BACKGROUND: The increasing prevalence of drug-resistant tuberculosis (TB) infection represents a global public health emergency. We evaluated the usefulness of a newly developed multiplexed, bead-based bioassay (Quantamatrix Multiplexed Assay Platform...
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Clostridium botulinum spores in Polish honey samples

Grenda T, Grabczak M, Sieradzki , Kwiatek K, Pohorecka , Skubida M, Bober A

The aim of this study was an examination of 240 multifloral honey samples collected from Polish apiaries to determine Clostridium botulinum occurrence. Honey was collected from apiaries directly after the...
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Serum Soluble Epidermal Growth Factor Receptor Level Increase in Patients Newly Diagnosed with Type 2 Diabetes Mellitus

Kim JM, Choung S, Joung KH, Lee JH, Kim HJ, Ku BJ

We analyzed circulating soluble epidermal growth factor receptor (sEGFR) levels in humans. Serum sEGFR levels were higher in subjects with newly diagnosed type 2 diabetes mellitus compared with controls. Serum...
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PCL/β-TCP Composite Scaffolds Exhibit Positive Osteogenic Differentiation with Mechanical Stimulation

Park SH, Park SA, Kang YG, Shin JW, Park YS, Gu SR, Wu YR, Wei J, Shin JW

We investigated the use of Polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) composites with applied mechanical stimulation as scaffold for bone tissue engineering. PCL-based three-dimensional (3D) structures were fabricated in a solvent-free process...
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Frequency and Type of Disputed rpoB Mutations in Mycobacterium tuberculosis Isolates from South Korea

Jo KW, Lee S, Kang MR, Sung H, Kim MN, Shim TS

BACKGROUND: A disputed rpoB mutation is a specific type of rpoB mutation that can cause low-level resistances to rifampin (RIF). Here, we aimed to assess the frequency and types of...
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Distinguishing Tendon and Ligament Fibroblasts Based on ¹H Nuclear Magnetic Resonance Spectroscopy

Ban HY, Shin JW, Chun SI, Kang YG, Wu Y, Kim JE, Lee EJ, Kim MJ, Mun CW, Shin JW

Tendon and ligament (T/L) have been known to be obviously different from each other in tissue level. However, due to the overlapping gene markers, distinction in cellular level has not...
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Arabidopsis thaliana as Bioindicator of Fungal VOCs in Indoor Air

Lee S, Hung R, Yin G, Klich MA, Grimm C, Bennett JW

In this paper, we demonstrate the ability of Arabidopsis thaliana to detect different mixtures of volatile organic compounds (VOCs) emitted by the common indoor fungus, Aspergillus versicolor, and demonstrate the...
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Antifilarial and Antibiotic Activities of Methanolic Extracts of Melaleuca cajuputi Flowers

Al-Abd NM, Nor ZM, Mansor M, Hasan MS, Kassim M

We evaluated the activity of methanolic extracts of Melaleuca cajuputi flowers against the filarial worm Brugia pahangi and its bacterial endosymbiont Wolbachia. Anti-Wolbachia activity was measured in worms and in...
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Mycoherbicidal Potential of Phaeoacremonium italicum, A New Pathogen of Eichhornia crassipes Infesting Harike Wetland, India

Singh B, Saxena S, Meshram V, Kumar M

Mycoherbicides are exclusive biotechnology products which offer a non-chemical solution to control noxious weeds on the land as well as aquatic in systems, viz a viz saving environment from hazardous...
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Clinical Implication of TSH Receptor Antibody Measurement

Shin DY

Autoantibodies directed against the thyrotropin receptor have been well known to be an important pathogenesis of Graves' disease. However, the diagnosis and management of Graves' disease are still mainly dependent...
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Classical natural ovine scrapie prions detected in practical volumes of blood by lamb and transgenic mouse bioassays

Dassanayake RP, Truscott T, Zhuang D, Schneider , Madsen-Bouterse SA, Young AJ, Stanton JB, Davis WC, O'Rourke K

Scrapie is diagnosed antemortem in sheep by detecting misfolded isoforms of prion protein (PrP(Sc)) in lymphoid follicles of the rectal mucosa and nictitating membranes. Assay sensitivity is limited if (a)...
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Neuroprotective and Antioxidant Effects of Novel Benzofuran-2-Carboxamide Derivatives

Cho J, Park C, Lee Y, Kim S, Bose S, Choi M, Kumar AS, Jung JK, Lee H

In the present study, we synthesized a series of novel 7-methoxy-N-(substituted phenyl)benzofuran-2-carboxamide derivatives in moderate to good yields and evaluated their neuroprotective and antioxidant activities using primary cultured rat cortical...
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Monomelic Amyotrophy (Hirayama Disease) With Upper Motor Neuron Signs: A Case Report

Yoo SD, Kim HS, Yun DH, Kim DH, Chon J, Lee SA, Lee SY, Han YJ

Monomelic amyotrophy (MMA), also known as Hirayama disease, is a sporadic juvenile muscular atrophy in the distal upper extremities. This disorder rarely involves proximal upper extremities and presents minimal sensory...
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Phenotypic and Functional Analysis of HL-60 Cells Used in Opsonophagocytic-Killing Assay for Streptococcus pneumoniae

Kim KH, Seoh JY, Cho SJ

Differentiated HL-60 is an effector cell widely used for the opsonophagocytic-killing assay (OPKA) to measure efficacy of pneumococcal vaccines. We investigated the correlation between phenotypic expression of immunoreceptors and phagocytic...
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Scolicidal Effects of Black Cumin Seed (Nigella sativa) Essential Oil on Hydatid Cysts

Mahmoudvand H, Dezaki ES, Kheirandish F, Ezatpour B, Jahanbakhsh S, Harandi MF

Surgery remains the preferred treatment for hydatid cyst (cystic echinococcosis, CE). Various scolicidal agents have been used for inactivation of protoscolices during surgery, but most of them are associated with...
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Biological Control of Aphid Using Fungal Culture and Culture Filtrates of Beauveria bassiana

Kim JJ, Jeong G, Han JH, Lee S

  • KMID: 2312706
  • Mycobiology.
  • 2013 Dec;41(4):221-224.
Aphids are one of the most destructive pests in crop production such as pepper, cucumber, and eggplants. The importance of entomopathogenic fungi as alternative pest control agents is increasing. Conidia...
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Nongoitrous autoimmune thyroiditis with facial palsy

Lee HJ, Kim JK

We report a case of severe hypothyroidism with nongoitrous, autoimmune thyroiditis and pituitary hyperplasia in a 13-year-old boy, who presented with sudden palsy on the left side of his face....
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