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A brief review of relationship between occupational benzene exposure and hematopoietic cancer

Yoon JH, Kwak WS, Ahn YS

We reviewed articles to clarify the current evidence status for 1) types of cancer which related to benzene exposure, and 2) certain benzene exposure level which might cause the hematopoietic...
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Indolent B-Cell Lymphoid Malignancy in the Spleen of a Man Who Handled Benzene: Splenic Marginal Zone Lymphoma

Lee J, Kang YJ, Ahn J, Song SH

We present the case of a 45-year-old man with a history of benzene exposure who developed splenic marginal zone lymphoma. For 6 years, he had worked in an enclosed space cleaning...
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Urinary Trans, Trans-Muconic Acid is Not a Reliable Biomarker for Low-level Environmental and Occupational Benzene Exposures

Jalai A, Ramezani Z, Ebrahim K

BACKGROUND: Benzene is a known occupational and environmental pollutant. Its urinary metabolite trans, trans-muconic acid (tt-MA) has been introduced by some environmental and occupational health regulatory associations as a biological...
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Modeling the effects of pollutant emissions from large industrial complexes on benzene, toluene, and xylene concentrations in urban areas

Bang JH, Oh I, Kim S, You S, Kim Y, Kwon HJ, Kim GB

This study utilized the Community Multiscale Air Quality model to simulate the spatial distribution of benzene, toluene, and xylene (BTX) concentrations from large national industrial complexes (IC) located in the...
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Estimating Benzene Exposure Level over Time and by Industry Type through a Review of Literature on Korea

Park D, Choi S, Ha K, Jung H, Yoon C, Koh DH, Ryu S, Kim S, Kang D, Yoo K

The major purpose of this study is to construct a retrospective exposure assessment for benzene through a review of literature on Korea. Airborne benzene measurements reported in 34 articles were...
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Early Liver and Kidney Dysfunction Associated with Occupational Exposure to Sub-Threshold Limit Value Levels of Benzene, Toluene, and Xylenes in Unleaded Petrol

Neghab M, Hosseinzadeh K, Hassanzadeh J

BACKGROUND: Unleaded petrol contains significant amounts of monocyclic aromatic hydrocarbons such as benzene, toluene, and xylenes (BTX). Toxic responses following occupational exposure to unleaded petrol have been evaluated only in...
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The Serine Protease Inhibitor, 4-(2-aminoethyl) Benzene Sulfonyl Fluoride Hydrochloride, Reduces Allergic Inflammation in a House Dust Mite Allergic Rhinitis Mouse Model

Kim BY, Park HR, Shin JH, Kim SW, Cho JH, Park YJ, Kim SW

PURPOSE: Serine protease inhibitors are involved in immune development, anti-inflammatory mechanisms, and tissue repair. In the present study, the serine protease inhibitor 4-(2-aminoethyl) benzene sulfonyl fluoride hydrochloride (AEBSF) was evaluated...
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Simultaneous Occurrence of Gallbladder Cancer in a Laundry Couple: Association between Gallbladder Cancer and Benzene

Shim KY, Cha SW, Um WH, Chun CG, Jeong SW, Jang JY, Cho YD

Gallbladder (GB) cancer occurs predominately as a biliary tract malignant tumor. It generally has a very poor prognosis, and early detection is often difficult. A variety of carcinogens have been...
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Urinary Hippuric Acid and trans,trans-Muconic Acid Levels According to Commuting Mode and Duration, Residential Environment, and Intake of Preservative-Added Foods and Beverages in University Students

Kim KM, Eom SY, Yim DH, Moon SI, Kim YD, Kim H

  • KMID: 2035675
  • Korean J Occup Environ Med.
  • 2012 Mar;24(1):61-71.
OBJECTIVES: Automobile exhaust gases contain benzene and toluene, which are excreted in human urine as trans,trans-muconic acid and hippuric acid, respectively. Sorbic acid and benzoic acid, used as food preservatives,...
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Hematological Evidence of Occupational Exposure to Chemicals and Other Factors among Auto-Repair Workers in Rawalpindi, Pakistan

Kamal A, Malik RN

Objectives Occupational exposure to aromatic solvents causes many serious health hazards to workers, especially if an ambient environment increases the exposure during routine working hours. This study was conducted on two...
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The Characteristics of the Appearance and Health Risks of Volatile Organic Compounds in Industrial (Pohang, Ulsan) and Non-Industrial (Gyeongju) Areas

Jung JH, Choi BW, Kim MH, Baek SO, Lee GW, Shon BH

  • KMID: 2380179
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012012.
OBJECTIVES: The aim of this study was to identify the health and environmental risk factors of air contaminants that influence environmental and respiratory diseases in Gyeongju, Pohang and Ulsan in...
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Polymorphisms in genes involved in innate immunity and susceptibility to benzene-induced hematotoxicity

Shen M, Zhang L, Lee KM, Vermeulen , Hosgood HD, Li G, Yin S, Rothman N, Chanock S, Smith MT, Lan Q

Benzene, a recognized hematotoxicant and carcinogen, can damage the human immune system. We studied the association between single nucleotide polymorphisms (SNPs) in genes involved in innate immunity and benzene hematotoxicity...
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Quantitative Exposure Assessment of Various Chemical Substances in a Wafer Fabrication Industry Facility

Park H, Jang JK, Shin JA

  • KMID: 2316999
  • Saf Health Work.
  • 2011 Mar;2(1):39-51.
OBJECTIVES: This study was designed to evaluate exposure levels of various chemicals used in wafer fabrication product lines in the semiconductor industry where work-related leukemia has occurred. METHODS: The research focused...
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Characteristics of Occupational Exposure to Benzene during Turnaround in the Petrochemical Industries

Chung EK, Shin JA, Lee BK, Kwon J, Lee N, Chung KJ, Lee JH, Lee IS, Kang SK, Jang JK

  • KMID: 2316976
  • Saf Health Work.
  • 2010 Sep;1(1):51-60.
OBJECTIVES: The level of benzene exposure in the petrochemical industry during regular operation has been well established, but not in turnaround (TA), where high exposure may occur. In this study,...
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The Association between Trans, Trans-Muconic Acid as a Biomarker for Benzene Exposure and the Platelet Count

Min YS, Woo KH, Kim JS, Yoo JY, Lee K, Lim HS, Kim H

  • KMID: 2075053
  • Korean J Occup Environ Med.
  • 2010 Jun;22(2):95-101.
OBJECTIVE: Recent researches suggest that trans,trans-muconic acid (t,t-MA) would be an adequate metabolic biomarker for low-level benzene exposure. Few study have investigated the association between the t,t-MA and platelet count,...
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Occupational Lymphohematopoietic Cancer in Korea

Kim EA, Lee WJ, Son M, Kang SK

The purpose of this study was to review the existing studies on lymphohematopoietic (LHP) cancer in Korea, estimate the prevalence of workers exposed to carcinogens, and determine the population attributable...
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Benzene and toluene concentrations in a hemodialysis room in a medium sized South Korean city

Kang MS, Hong JR, Gil HW, Yang JO, Lee EY, Hong SY, Jun YT, Son BS

BACKGROUND/AIMS: The current study was designed to determine whether the indoor air pollution in a hemodialysis room (HD) was different from that of other comparable areas in a hospital....
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Change of Urinary Trans, Trans-Muconic Acid before and after Turnaround Process in a Petrochemical Plant

Kim SH, Park JU, Moon JD

  • KMID: 2033850
  • Korean J Occup Environ Med.
  • 2008 Dec;20(4):335-342.
OBJECTIVES: This study was performed to estimate the exposure to benzene, one of the most serious health hazards, in four phases of a turnaround in a petrochemical company, and to...
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Occupational Malignant Lymphohematopoietic Diseases Compensated under the Industrial Accident Compensation Insurance from 1996 to 2005

Ahn YS

  • KMID: 2028368
  • Korean J Occup Environ Med.
  • 2007 Jun;19(2):81-92.
OBJECTIVES: To analyze the characteristics of malignant occupational lymphohematopoietic diseases compensated under the Industrial Accident Compensation Insurance that is operated by the Korea Labor Welfare Corporation (KLWC). METHODS: Using the KLWC...
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Influences of GST Subfamily & NQO1 Gene Polymorphism on the Metabolism of Benzene

Jeong HS, Kim KW, Lee JE, Lee WT, Park KA, Chang SK

  • KMID: 1610764
  • Korean J Anat.
  • 2003 Aug;36(4):291-299.
The higher concentration of traces of aromatic hydrocarbons prevailing in the refinery atmosphere causes severe occupational health hazard to refinery workers. In this study, the biochemical role of genetic polymorphism...
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