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Endoscopic submucosal dissection in the West

Podboy A, Friedland

Endoscopic resection has emerged as the first line therapy for pre-malignant conditions throughout the gastrointestinal (GI) tract. Resection techniques have evolved from forceps avulsion and snare polypectomy to endoscopic mucosal...
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Diagnosis and Management of Barrett's Esophagus, Dysplasia and Early Esophageal Adenocarcinoma: Focusing on American and European Guidelines

Yoo AY, Joo MK

Barrett's esophagus (BE) is one of the most prominent diseases in Western countries because of its potential to progress to dysplasia or adenocarcinoma. Recently, the American College of Gastroenterology (ACG),...
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The Role of Gut Microbiota and Use of Probiotics in the Treatment of Upper Gastrointestinal Diseases

Lee MY, Choi SC, Kim YS

Gut microbiota have been known to play an essential role in host immunity and metabolism. Dysbiosis is associated with various gastrointestinal (GI) and other diseases such as cancers, metabolic diseases,...
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Buried Barrett's Esophagus with High-Grade Dysplasia after Radiofrequency Ablation

Castela J, Serrano M, de Ferro S, Pereira DV, Chaves P, Pereira AD

Radiofrequency ablation therapy is an effective endoscopic option for the eradication of Barrett's esophagus that appears to reduce the risk of esophageal cancer. A concern associated with this technique is...
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Screening for Barrett's Esophagus: Balancing Clinical Value and Cost-effectiveness

Patel A, Gyawali CP

  • KMID: 2449090
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):181-188.
  • doi: 10.5056/jnm18156
In predisposed individuals with long standing gastroesophageal reflux disease (GERD), esophageal squamous mucosa can transform into columnar mucosa with intestinal metaplasia, commonly called Barrett's esophagus (BE). Barrett's mucosa can develop...
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Quality Indicators in Barrett's Esophagus: Time to Change the Status Quo

Han S, Wani S

The push for high quality care in all fields of medicine highlights the importance of establishing and adhering to quality indicators. In response, several gastrointestinal societies have established quality indicators...
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Current and Future Use of Esophageal Capsule Endoscopy

Park J, Cho YK, Kim JH

Capsule endoscopy can be a diagnostic option for patients with esophageal diseases who cannot tolerate esophagogastroduodenoscopy.Functional modifications of the capsule allow for thorough examination of the esophagus. Esophageal capsule endoscopy...
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Esophageal Motor Disorders Are a Strong and Independant Associated Factor of Barrett's Esophagus

Bazin C, Benezech A, Alessandrini M, Grimaud JC, Vitton V

  • KMID: 2413097
  • J Neurogastroenterol Motil.
  • 2018 Apr;24(2):216-225.
  • doi: 10.5056/jnm17090
BACKGROUND/AIMS: Esophageal motor disorder (EMD) has been shown to be associated with gastroesophageal reflux disease (GERD). However, the association of EMD with a Barrett's esophagus (BE) is controversial. Our objective...
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Impact of Obesity on a Chinese Population with Erosive Esophagitis and Barrett's Esophagus

Lee SW, Lien HC, Lee TY, Tung CF, Yeh HZ, Chang CS

BACKGROUND/AIMS: The aim of this study was to investigate the associations between obesity and erosive esophagitis (EE) or Barrett's esophagus (BE) in a Chinese population. METHODS: Data from subjects were retrospectively...
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Laser Imaging Facilitates Early Detection of Synchronous Adenocarcinomas in Patients with Barrett's Esophagus

Iwashita C, Miura Y, Osawa H, Takezawa T, Ino Y, Okada M, Lefor AK, Yamamoto H

Barrett's adenocarcinoma may occur in multiple sites, and recurrence and metachronous lesions are the major problems with endoscopic resection. Therefore, early detection of such lesions is ideal to achieve complete...
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Heterotopic bone formation in normal gastric cardiac mucosa

Eom SH, Park CH, Chung DW, Lee SH, Seo JY, Kim YS, Kwak DH, Kim JH

Heterotopic bone formation in the gastrointestinal tract is a rare phenomenon. Most reported cases were associated with benign and malignant neoplasms, except for a case in which heterotopic bone formation...
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Esophageal Acid Clearance During Random Swallowing Is Faster in Patients with Barrett's Esophagus Than in Healthy Controls

Lottrup C, Krarup AL, Gregersen , Ejstrud P, Drewes AM

  • KMID: 2433455
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):630-642.
  • doi: 10.5056/jnm16019
BACKGROUND/AIMS: Impaired esophageal acid clearance may be a contributing factor in the pathogenesis of Barrett’s esophagus. However, few studies have measured acid clearance as such in these patients. In this...
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Sex and Gender Differences in Gastroesophageal Reflux Disease

Kim YS, Kim N, Kim GH

  • KMID: 2433450
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):575-588.
  • doi: 10.5056/jnm16138
It is important to understand sex and gender-related differences in gastroesophageal reflux disease (GERD) because gender-related biologic factors might lead to better prevention and therapy. Non-erosive reflux disease (NERD) affects...
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A Case of Endoscopic Submucosal Dissection of Esophageal Adenocarcinoma Arising from Barrett's Esophagus

Kim JS, Kim BW

No abstract available.
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Does the Risk of Esophageal Adenocarcinoma Increase as the Length of Barrett's Esophagus Becomes Long?

Kim JG, Kim GH

No abstract available.
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Esophageal Stricture Prevention after Endoscopic Submucosal Dissection

Jain D, Singhal S

Advances in diagnostic modalities and improvement in surveillance programs for Barrett esophagus has resulted in an increase in the incidence of superficial esophageal cancers (SECs). SEC, due to their limited...
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Effect of 15 Minutes Brief Education for Medical Personnel in Diagnosing Barrett's Esophagus

Seo KI, Park MI, Park SJ, Moon W, Kim SE, Han YJ

BACKGROUND/AIMS: The higher prevalence of gastroesophageal reflux disease has preceded the increase of Barrett's esophagus and esophageal adenocarcinoma in Western countries. An increase of Barrett's esophagus and esophageal adenocarcinoma can...
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Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions

Lee SK

Confocal laser endomicroscopy (CLE) is a new technology enabling endoscopists to visualize tissue at the cellular level. CLE has the fundamental potential to provide a histologic diagnosis, and may theoretically...
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Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy?

Lee HJ, Kim B, Kim DW, Park JC, Shin SK, Lee YC, Lee SK

PURPOSE: During sedated esophagogastroduodenoscopy (EGD), patients may not be able to perform inspiration, which is necessary to examine the esophagogastric junction. Therefore sedation may affect diagnosis of gastroesophageal reflux-related findings....
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Unmet Needs in the Treatment of Gastroesophageal Reflux Disease

Dickman R, Maradey-Romero C, Gingold-Belfer R, Fass R

  • KMID: 2433470
  • J Neurogastroenterol Motil.
  • 2015 Jul;21(3):309-319.
  • doi: 10.5056/jnm15105
Gastroesophageal reflux disease (GERD) is a highly prevalent gastrointestinal disorder. Proton pump inhibitors have profoundly revolutionized the treatment of GERD. However, several areas of unmet need persist despite marked improvements...
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