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Interactions Between Atopic Dermatitis and Staphylococcus aureus Infection: Clinical Implications

Kim J, Kim BE, Ahn K, Leung DY

Staphylococcus aureus commonly colonizes the skin of atopic dermatitis (AD) patients and contributes to the development and exacerbation of AD. Multiple factors are associated with colonization of AD skin by...
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A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1 (KIM-1) and Detects KIM-1–Overexpressing Tumors In Vivo

Haque ME, Khan F, Chi L, Gurung S, Vadevoo SM, Park RW, Kim DK, Kim SK, Lee B

PURPOSE: This study was carried out to identify a peptide that selectively binds to kidney injury molecule-1 (KIM-1) by screening a phage-displayed peptide library and to use the peptide for...
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Development of a Pancreatic Cancer Specific Binding Peptide Using Phage Display

Lee DW, Park JM, Yang SM, Kwak MH, Roh YJ, Lee IS, Choi MG

BACKGROUND/AIMS: Pancreatic cancer has a very poor prognosis, and early diagnosis is a way to increase the survival rate of patients. The purpose of this study was to develop pancreatic...
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Specification of Bacteriophage Isolated Against Clinical Methicillin-Resistant Staphylococcus Aureus

Nasser A, Azizian R, Tabasi M, Khezerloo , Heravi FS, Kalani MT, Sadeghifard N, Amini R, Pakzad I, Radmanesh , Jalilian F

OBJECTIVES: The emergence of resistant bacteria is being increasingly reported around the world, potentially threatening millions of lives. Amongst resistant bacteria, methicillin-resistant Staphylococcus aureus (MRSA) is the most challenging to...
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Efficacy of Bacteriophages in Propionibacterium acnes-Induced Inflammation in Mice

Kim MJ, Eun DH, Kim SM, Kim J, Lee WJ

BACKGROUND: Bacteriophages have been introduced as living drugs for infectious diseases; thus, they may provide an alternative to conventional acne therapeutics in patients with non-responsive acne. OBJECTIVE: We investigated the effect...
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Role of Gut Microbiota in Type 2 Diabetes Mellitus and Its Complications: Novel Insights and Potential Intervention Strategies

Woldeamlak B, Yirdaw K, Biadgo B

Type 2 diabetes mellitus has become one of the fastest growing public health problems worldwide. The disease is believed to involve a complex process involving genetic susceptibility and environmental factors....
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A Salmonella Typhi ghost induced by the E gene of phage φX174 stimulates dendritic cells and efficiently activates the adaptive immune response

Won G, Eo SK, Park SY, Hur J, Lee JH

Previously, we genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost in stimulating the adaptive...
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Production and Storage of Virus Simulants

Shin IS, Kim D, Yang SJ, Lim BC, Cha Y, Kim S, Cho TJ

We have examined isolation and identification protocols for three virus simulant candidates to biological warfare agents. MS2 phage, a simulant for yellow fever virus and Hantaan virus, was propagated using...
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Biological control of Flavobacterium psychrophilum infection in ayu (Plecoglossus altivelis altivelis) using a bacteriophage PFpW-3

Kim JH, Park SC

The efficacy of using a bacteriophage (phage) to control Flavobacterium psychrophilum (F. psychrophilum) infection of ayu (Plecoglossus altivelis altivelis) was evaluated in this study. Intramuscular challenge failed to induce sufficient...
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In Silico Signature Prediction Modeling in Cytolethal Distending Toxin-Producing Escherichia coli Strains

Javadi M, Oloomi M, Bouzari S

In this study, cytolethal distending toxin (CDT) producer isolates genome were compared with genome of pathogenic and commensal Escherichia coli strains. Conserved genomic signatures among different types of CDT producer...
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Next-generation sequencing enables the discovery of more diverse positive clones from a phage-displayed antibody library

Yang W, Yoon A, Lee S, Kim S, Han J, Chung J

Phage display technology provides a powerful tool to screen a library for a binding molecule via an enrichment process. It has been adopted as a critical technology in the development...
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From rabbit antibody repertoires to rabbit monoclonal antibodies

Weber J, Peng H, Rader C

In this review, we explain why and how rabbit monoclonal antibodies have become outstanding reagents for laboratory research and increasingly for diagnostic and therapeutic applications. Starting with the unique ontogeny...
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Engineered M13 Nanofiber Accelerates Ischemic Neovascularization by Enhancing Endothelial Progenitor Cells

Lee JH, Kim SW, Ji ST, Kim YJ, Jang WB, Oh JW, Kim J, Yoo SY, Beak SH, Kwon SM

Dysfunction or loss of blood vessel causes several ischemic diseases. Although endothelial progenitor cells (EPCs) are a promising source for cell-based therapy, ischemia-induced pathophysiological condition limits the recovery rate by...
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Mimotopes for Api g 5, a Relevant Cross-reactive Allergen, in the Celery-Mugwort-Birch-Spice Syndrome

Lukschal A, Wallmann J, Bublin M, Hofstetter G, Mothes-Luksch N, Breiteneder H, Pali-Scholl I, Jensen-Jarolim E

PURPOSE: In the celery-mugwort-birch-spice syndrome, a significant proportion of IgE is directed against high molecular weight (HMW) glycoproteins, including the celery allergen Api g 5. BIP3, a monoclonal antibody originally...
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Nutritional Status and Body Composition in Korean Myopathy Patients

Jang SY, Kang SW, Choi WA, Lee JW, Suh MR, Lee SM, Park YK

In myopathy patients, fat mass increases as the disease progresses, while lean body mass decreases. The present study aimed to investigate the overall nutritional status of Korean myopathy patients through...
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Establishment of a live vaccine strain against fowl typhoid and paratyphoid

Cho SH, Ahn YJ, Kim TE, Kim SJ, Huh W, Moon YS, Lee BH, Kim JH, Kwon HJ

To develop a live vaccine strain against fowl typhoid and paratyphoid caused by Salmonella serovar Gallinarum biovar Gallinarum (Salmonella Gallinarum) and Salmonella serovar Enteritidis (Salmonella Enteritidis), respectively, several nalidixic acid...
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Specific B-cell Epitope of Per a 1: A Major Allergen of American Cockroach (Periplaneta americana) and Anatomical Localization

Sookrung N, Khetsuphan T, Chaisri U, Indrawattana N, Reamtong O, Chaicumpa , Tungtrongchitr A

PURPOSE: Cockroach (CR) is a common source of indoor allergens, and Per a 1 is a major American CR (Periplaneta americana) allergen; however, several attributes of this protein remain unknown....
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A Virulent Salmonella enterica Serovar Enteritidis Phage SE2 with a Strong Bacteriolytic Activity of Planktonic and Biofilmed Cells

Tiwari BR, Kim S, Kim J

Salmonella enterica serovar Enteritidis is one of the major food borne pathogens. Utilizing lytic bacteriophages against this pathogen can be a new and effective approach for the prevention of food-contamination...
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Comparative Viral Metagenomics of Environmental Samples from Korea

Kim MS, Whon TW, Bae JW

The introduction of metagenomics into the field of virology has facilitated the exploration of viral communities in various natural habitats. Understanding the viral ecology of a variety of sample types...
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Field evaluation of Enterotoxigenic Escherichia coli-specific bacteriophage (PhiCJ19) as a feed additive

Yoo A, Cha SB, Shin MK, Park HT, Seo HS, Kim JW, Yoo HS

  • KMID: 1991775
  • Korean J Vet Res.
  • 2013 Jun;53(2):83-88.
Field efficacy of enterotoxigenic Escherichia coli-specific phage (PhiCJ19) as a feed additive was evaluated in weaning piglets. Fifty-four piglets at 3~4 weeks old were allocated in three different groups and...
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