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The Natural Course of Total Kidney Volume in Patients with Autosomal Dominant Polycystic Kidney Disease undergoing Hemodialysis

Kim YN, Jung Y, Shin HS, Rim H, Park JG, Lee DY, Kim JK

Objectives: The natural course of native kidneys after hemodialysis initiation in patients with autosomal dominant polycystic kidney disease (ADPKD) remains poorly understood. Methods: We measured the total volumes of native kidneys...
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Clinical and genetic characteristics of Korean autosomal dominant polycystic kidney disease patients

Oh YK, Park HC, Ryu H, Kim YC, Oh KH

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. It is characterized by cyst growth in the kidneys, resulting in kidney enlargement and end-stage kidney disease....
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Comparison of chronic kidney disease trial designs and analysis strategies

Lawrence J

Background: Despite the large burden of chronic kidney disease (CKD), it is challenging to conduct adequately powered clinical trials in this setting. Sound and efficient trials are needed to advance...
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Long-term Tolvaptan Treatment of Autosomal Dominant Polycystic Kidney Disease in Korea

Kim HY, Lee SJ, Kim BK, Kim M, Bae EH, Ma SK, Kim SW

A 22-year-old male patient was diagnosed with autosomal dominant polycystic kidney disease (ADPKD). He received conservative treatment with an angiotensin-converting enzyme inhibitor. Two years later, oral therapy, consisting of 60...
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Esophageal Artery Pseudoaneurysm and Takayasu Arteritis in a Patient with Autosomal Dominant Polycystic Kidney Disease

Kim H, Yu Y, Shim KE, Kim JE, Koh J, Yoon JW, Ahn C, Oh YK

A 47-year-old female previously diagnosed with ADPKD visited the hospital due to sudden pain in her upper abdomen and back. Esophagogastroduodenoscopy, contrast-enhanced abdominal computed tomography (CT), and CT angiography identified...
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Autosomal Dominant Polycystic Kidney Desease Coexisting with Renal Dysplasia. First Case Described and Followed Since Prenatal Period

Truyols C

Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent hereditary renal disease and causes terminal chronic renal failure. ADPKD is characterized by bilateral multiple renal cysts, which are produced...
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Hypokalemic Hypertension Leading to a Diagnosis of Autosomal Dominant Polycystic Kidney Disease

Vutthikraivit W, Assanatham M, Sriphrapradang C

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease. Hypertension is common and occurs before decline in renal function. However, the coexistence of hypertension and hypokalemia...
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Two cases of TSC2/PKD1 contiguous gene deletion syndrome

You J, Kang E, Kim Y, Lee BH, Ko TS, Kim GH, Choi JH, Yoo HW

Tuberous sclerosis complex (TSC, MIM#191100) is an autosomal dominant neurocutaneous syndrome caused by mutation or deletion of TSC1 encoding hamartin or TSC2 encoding tuberin and characterized by seizure, mental retardation,...
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PKD2 mutation in an Iranian autosomal dominant polycystic kidney disease family with misleading linkage analysis data

Entezam M, Khatami MR, Saddadi F, Ayati M, Roozbeh J, Keramatipour M

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic renal disorder caused by mutation in 2 genes PKD1 and PKD2. Thus far, no mutation is identified in...
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A Case of Non ST Elevation Myocardial Infarction by Coronary Artery Focal Spasm in a Patient with Autosomal Dominant Polycystic Kidney Disease

Lee DW, Pyeon SI, Oh KJ, Park HJ, Chae CB, Choi JH, Kim JH

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease. The main causes of death in ADPKD are cardiovascular disease as well as infections and neurological reasons....
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Multiple Cardiovascular Manifestations in a Patient with Autosomal Dominant Polycystic Kidney Disease

Kang YR, Ahn JH, Kim KH, Choi YM, Choi J, Park JR

Autosomal dominant polycystic kidney disease (ADPKD) is a systemic disorder associated with various extrarenal complications. The major cardiovascular complications of ADPKD include valvulopathies and vascular ectasia. A 64-year-old man who...
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Autosomal Dominant Polycystic Kidney Disease Combined with Intracranial Aneurysm and Dilated Cardiomyopathy: A Case Report

Chung BM, Chong S, Lee WS, Hwang SN

Extrarenal manifestations of autosomal dominant polycystic kidney disease (ADPKD) include non-renal, various intracranial, and cardiac cysts. A 26-year-old man with presumed ADPKD was also diagnosed with hemoptysis and dyspnea. The...
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Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease

Lee SH, Somlo S

  • KMID: 2224270
  • Kidney Res Clin Pract.
  • 2014 Jun;33(2):73-78.
The primary cilium of renal epithelia acts as a transducer of extracellular stimuli. Polycystin (PC)1 is the protein encoded by the PKD1 gene that is responsible for the most common...
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Successfully Treated Escherichia coli-Induced Emphysematous Cyst Infection with Combination of Intravenous Antibiotics and Intracystic Antibiotics Irrigation in a Patient with Autosomal Dominant Polycystic Kidney Disease

Kim H, Cho Park H, Lee S, Lee J, Cho C, Kim DK, Hwang YH, Oh KH, Ahn C

A 62-yr-old woman with an autosomal dominant polycystic kidney disease (ADPKD) was admitted to our hospital for further evaluation of intermittent fever, nausea and left flank discomfort. The computed tomography...
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Transcatheter Arterial Embolization Using Ethanol in a Dialysis Patient for Contracting Enlarged Polycystic Kidneys

Rim H, Jung GS, Jung YS

The mass effect of nephromegaly in patients with autosomal dominant polycystic kidney disease may cause pain and symptoms by compressing the alimentary tract, lungs, and heart. Conventional therapies exist to...
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Cyst Ablation Using a Mixture of N-Butyl Cyanoacrylate and Iodized Oil in Patients with Autosomal Dominant Polycystic Kidney Disease: the Long-Term Results

Kim SH, Kim SH, Cho JY

OBJECTIVE: We wanted to assess the long-term results of cyst ablation with using N-butyl cyanoacrylate (NBCA) and iodized oil in patients with autosomal dominant polycystic kidney disease (ADPKD) and symptomatic...
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Sequential vs. Simultaneous Bilateral Native Nephrectomy and Renal Transplantation for Autosomal Dominant Polycystic Kidney Disease

Hong J, Kim SJ, Lee SK, Joh JW, Kwon CH, Choi GS, Park JB

  • KMID: 2324412
  • J Korean Soc Transplant.
  • 2008 Dec;22(2):248-253.
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited kidney diseases and a frequent cause of end-stage renal failure. Generally accepted indications of nephrectomy in...
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Caroli's Disease Combined with Colon Cancer and Polycystic Kidney Disease

Chae YJ, Choi CY, Kim JY, Shin HW, Kim YS, Choi MH, Jang HJ, Eun CS, Kae SH, Lee J

  • KMID: 2143680
  • Korean J Gastrointest Endosc.
  • 2006 Jan;32(1):71-74.
Caroli's disease is defined as a communication between congenital cystic dilatation of the bile duct and the biliary system. Caroli's disease accompanied with autosomal dominant polycystic kidney disease is a...
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Apoptosis in Autosomal Dominant Polycystic Kidney Disease

Lhee HY, Lee KB, Kim H, Chae SW, Park MH

  • KMID: 2254246
  • Korean J Nephrol.
  • 2005 May;24(3):366-374.
BACKGROUND: Apoptosis is one of the major histopathologic features of autosomal dominant polycystic kidney disease (ADPKD) and may be causally related to the cystogenesis and the progressive deterioration of the...
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A case of renal arterial embolization using 99% ethanol and lipiodol mixture for autosomal dominant polycystic kidney disease in a hemodialysis patient

Chang T, Ryu DR, Kim BS, Jung S, Shim CY, Kang EW, Shin SK

  • KMID: 1927309
  • Korean J Med.
  • 2004 Nov;67(Suppl 3):S776-S780.
Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder characterized by innumerable bilateral renal cysts. It has an prevalence rate of one in 200~1,000 individuals and is a...
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