- Combined Aerobic and Resistance Exercise Training Reduces Circulating Apolipoprotein J Levels and Improves Insulin Resistance in Postmenopausal Diabetic Women
-
Jeon YK, Kim SS, Kim JH, Kim HJ, Kim HJ, Park JJ, Cho YS, Joung SH, Kim JR, Kim BH, Song SH, Kim IJ, Kim YK, Kim YB
- KMID: 2470959
- Diabetes Metab J.
- 2020 Feb;44(1):103-112.
- doi: 10.4093/dmj.2018.0160
BACKGROUND: Circulating apolipoprotein J (ApoJ) is closely associated with insulin resistance; however, the effect of exercise on circulating ApoJ levels and the association of ApoJ with metabolic indices remain unknown.... -
- CITED
-
- Close
- SHARE
-
- Close
- Efficacy and Safety of High-Dose Atorvastatin in Moderate-to-High Cardiovascular Risk Postmenopausal Korean Women with Dyslipidemia
-
Moon J, Yoo S, Koh G, Min KW, Shin HH
- KMID: 2470808
- J Lipid Atheroscler.
- 2020 Jan;9(1):162-171.
- doi: 10.12997/jla.2020.9.1.162
OBJECTIVE: Postmenopausal women show a more atherogenic lipid profile and elevated cardiovascular risk compared to premenopausal women. The aim of this study was to investigate the efficacy and safety of... -
- CITED
-
- Close
- SHARE
-
- Close
- A Critical Role of PCSK9 in Mediating IL-17-Producing T Cell Responses in Hyperlipidemia
-
Kim YU, Kee P, Danila D, Teng BB
- KMID: 2466611
- Immune Netw.
- 2019 Dec;19(6):e41.
- doi: 10.4110/in.2019.19.e41
We previously demonstrated that atherogenic Ldlr(−/−)Apobec1(−/−) (LDb) double knockout mice lacking both low-density lipoprotein receptor (LDLR) and apolipoprotein B mRNA-editing catalytic polypeptide-1 (Apobec1) had increased serum IL-17 levels, with T... -
- CITED
-
- Close
- SHARE
-
- Close
- Efficacy and safety of alirocumab in Korean patients with hypercholesterolemia and high cardiovascular risk: subanalysis of the ODYSSEY-KT study
-
Nam CW, Kim DS, Li J, Baccara-Dinet MT, Li I, Kim JH, Kim CJ
- KMID: 2463483
- Korean J Intern Med.
- 2019 Nov;34(6):1252-1262.
- doi: 10.3904/kjim.2018.133
BACKGROUND/AIMS: Efficacy and safety data of alirocumab, a fully human monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9), is not yet well established in the Korean population. We assessed... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus
-
Hwang YC, Jun JE, Jeong IK, Ahn KJ, Chung HY
- KMID: 2460952
- Diabetes Metab J.
- 2019 Oct;43(5):582-589.
- doi: 10.4093/dmj.2018.0124
BACKGROUND: The apolipoprotein B/A1 (apoB/A1) ratio is a stronger predictor of future cardiovascular disease than is the level of conventional lipids. Statin and ezetimibe combination therapy have shown additional cardioprotective... -
- CITED
-
- Close
- SHARE
-
- Close
- The Association between the Apolipoprotein E Gene Polymorphism and All-cause Mortality in the Korean Population
-
Choi CK, Kweon SS, Lee YH, Nam HS, Park KS, Ryu SY, Choi SW, Kim HY, Shin MH
- KMID: 2460038
- J Korean Med Sci.
- 2019 Oct;34(40):e269.
- doi: 10.3346/jkms.2019.34.e269
BACKGROUND: Apolipoprotein E (APOE) gene polymorphism is associated with neurodegenerative and cardiovascular diseases. Although the effects of the gene differ by ethnic group, few studies have examined Asians. Therefore, the... -
- CITED
-
- Close
- SHARE
-
- Close
- The Potential Role of Biomarkers Associated with ASCVD Risk: Risk-Enhancing Biomarkers
-
Choi S
- KMID: 2458382
- J Lipid Atheroscler.
- 2019 Sep;8(2):173-182.
- doi: 10.12997/jla.2019.8.2.173
Serum cholesterol is major risk factor and contributor to atherosclerotic cardiovascular disease (ASCVD). Therapeutic cholesterol-lowering drugs, especially statin, revealed that reduction in low-density lipoprotein cholesterol (LDL-C) produces marked reduction of... -
- CITED
-
- Close
- SHARE
-
- Close
- Anhedonia and Dysphoria Are Differentially Associated with the Risk of Dementia in the Cognitively Normal Elderly Individuals: A Prospective Cohort Study
-
Lee JR, Suh SW, Han JW, Byun S, Kwon SJ, Lee KH, Kwak KP, Kim BJ, Kim SG, Kim JL, Kim TH, Ryu SH, Moon SW, Park JH, Lee DW, Youn JC, Lee DY, Lee SB, Lee JJ, Jhoo JH, Kim KW
- KMID: 2456166
- Psychiatry Investig.
- 2019 Aug;16(8):575-580.
- doi: 10.30773/pi.2019.06.07
OBJECTIVE: We investigated the impact of depressed mood (dysphoria) and loss of interest or pleasure (anhedonia)on the risk of dementia in cognitively-normal elderly individuals. METHODS: This study included 2,685 cognitively-normal elderly... -
- CITED
-
- Close
- SHARE
-
- Close
- Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes
-
He P, Tian N
- KMID: 2443606
- Korean J Physiol Pharmacol.
- 2019 May;23(3):181-189.
- doi: 10.4196/kjpp.2019.23.3.181
Curcumin, an active ingredient of Curcuma longa L., can reduce the concentration of low-density lipoproteins in plasma, in different ways. We had first reported that curcumin exhibits hypocholesterolemic properties by... -
- CITED
-
- Close
- SHARE
-
- Close
- Daily walnut intake improves metabolic syndrome status and increases circulating adiponectin levels: randomized controlled crossover trial
-
Hwang HJ, Liu Y, Kim HS, Lee H, Lim Y, Park H
- KMID: 2442367
- Nutr Res Pract.
- 2019 Apr;13(2):105-114.
- doi: 10.4162/nrp.2019.13.2.105
BACKGROUND/OBJECTIVES: Several previous studies have investigated whether regular walnut consumption positively changes heart-health-related parameters. The aim of this study was to investigate the effects of daily walnut intake on metabolic... -
- CITED
-
- Close
- SHARE
-
- Close
- Apolipoprotein E Genotype and Expression Correlated with Hepatitis C Virus Genotype and Infection
-
Park GN, Jo HJ, Kim HR, Kim MJ, Shin KA, Hong SB, Chang KS
- KMID: 2442585
- J Bacteriol Virol.
- 2019 Mar;49(1):27-38.
- doi: 10.4167/jbv.2019.49.1.27
The hepatitis C virus (HCV) is a globally prevalent human pathogen that causes persistent liver infections in most infected individuals. Several studies reported that HCV particles are enriched in apolipoprotein... -
- CITED
-
- Close
- SHARE
-
- Close
- Genetics of Alzheimer's Disease
-
Kim JH
- KMID: 2442783
- Dement Neurocogn Disord.
- 2018 Dec;17(4):131-136.
- doi: 10.12779/dnd.2018.17.4.131
Alzheimer's disease (AD) related genes have been elucidated by advanced genetic techniques. Familial autosomal dominant AD genes founded by linkage analyses are APP, PSEN1, PSEN2, ABCA7, and SORL1. Genome-wide association... -
- CITED
-
- Close
- SHARE
-
- Close
- Report on the External Quality Assessment Scheme for Molecular Diagnostics in Korea (2017)
-
Kim MJ, Yoon MH, Song JY, Cho SI, Park SS, Seong MW
- KMID: 2437188
- J Lab Med Qual Assur.
- 2018 Dec;40(4):199-210.
- doi: 10.15263/jlmqa.2018.40.4.199
Quality control for genetic analysis has become more important with a drastic increase in testing volume and clinical demands. The molecular diagnostics division of the Korean Association of Quality Assurance... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Maternal and Post-Weaning High-Fat Diet on Leptin Resistance and Hypothalamic Appetite Genes in Sprague Dawley Rat Offspring
-
Choi JS
- KMID: 2424303
- Clin Nutr Res.
- 2018 Oct;7(4):276-290.
- doi: 10.7762/cnr.2018.7.4.276
The defective satiation signaling may contribute to the etiology of obesity. We investigated how dietary modification during maternal (pregnancy and lactation) and post-weaning affects obesity, insulin resistance (IR) and hypothalamic... -
- CITED
-
- Close
- SHARE
-
- Close
- Postprandial Lipid Concentrations and Daytime Biological Variation of Lipids in a Healthy Chinese Population
-
Yang D, Cai Q, Qi X, Zhou Y
- KMID: 2434732
- Ann Lab Med.
- 2018 Sep;38(5):431-439.
- doi: 10.3343/alm.2018.38.5.431
BACKGROUND: Several latest guidelines and consensus statements from Europe and the United States specify that there is no need for fasting prior to routine lipid tests. However, the latest Chinese... -
- CITED
-
- Close
- SHARE
-
- Close
- Pathologically Confirmed Cerebral Amyloid Angiopathy with No Radiological Sign in a Patient with Early Onset Alzheimer's Disease
-
Kim SJ, Seo Y, Kim HJ, Na DL, Seo SW, Kim Y, Suh YL
- KMID: 2415541
- Yonsei Med J.
- 2018 Aug;59(6):801-805.
- doi: 10.3349/ymj.2018.59.6.801
Cerebral amyloid angiopathy (CAA) is associated with perivascular disruption, which is caused by progressive amyloid-beta (Aβ) deposition in vessels. Previous autopsy studies have shown that the prevalence of CAA in... -
- CITED
-
- Close
- SHARE
-
- Close
- Changes in the Hippocampal Volume and Shape in Early-Onset Mild Cognitive Impairment
-
Moon SW, Lee B, Choi YC
- KMID: 2462794
- Psychiatry Investig.
- 2018 May;15(5):531-537.
- doi: 10.30773/pi.2018.02.12
OBJECTIVE: The aim of this study was to examine the change in the hippocampal volume and shape in early-onset mild cognitive impairment (EO-MCI) associated with the APOE ε4 carrier state. METHODS:... -
- CITED
-
- Close
- SHARE
-
- Close
- Predictors of Institutionalization in Patients with Alzheimer's Disease in South Korea
-
Park DG, Lee S, Moon YM, Na DL, Jeong JH, Park KW, Lee YH, Lim TS, Choi SH, Moon SY
- KMID: 2407946
- J Clin Neurol.
- 2018 Apr;14(2):191-199.
- doi: 10.3988/jcn.2018.14.2.191
BACKGROUND AND PURPOSE: We investigated predictors of institutionalization in patients with Alzheimer's disease (AD) in South Korea. METHODS: In total, 2,470 patients with AD aged 74.5±7.8 years (mean±standard deviation, 68.1% females)... -
- CITED
-
- Close
- SHARE
-
- Close
- Rapid Changes in Serum Lipid Profiles during Combination Therapy with Daclatasvir and Asunaprevir in Patients Infected with Hepatitis C Virus Genotype 1b
-
Chida T, Kawata K, Ohta K, Matsunaga , Ito J, Shimoyama , Yamazaki S, Noritake H, Suzuki T, Suda T, Kobayashi
- KMID: 2429075
- Gut Liver.
- 2018 Mar;12(2):201-207.
- doi: 10.5009/gnl17179
BACKGROUND/AIMS: Changes in lipid profiles in patients infected with hepatitis C virus (HCV) during direct-acting antiviral therapy have been reported in recent years. However, the clinical aspects of disturbed lipid... -
- CITED
-
- Close
- SHARE
-
- Close
- Apolipoprotein A5 3'-UTR variants and cardiometabolic traits in Koreans: results from the Korean genome and epidemiology study and the Korea National Health and Nutrition Examination Survey
-
Kim OY, Moon J, Jo G, Kwak SY, Kim JY, Shin MJ
- KMID: 2429020
- Nutr Res Pract.
- 2018 Feb;12(1):61-68.
- doi: 10.4162/nrp.2018.12.1.61
BACKGROUND/OBJECTIVES: This study aimed to test the association between APOA5 3'-UTR variants (rs662799) and cardiometabolic traits in Koreans. SUBJECTS/METHODS: For this study, epidemiological data, Apolipoprotein A5 (APOA5) genotype information, and lymphoblastoid... -
- CITED
-
- Close
- SHARE
-
- Close
