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Antimicrobial Therapy and Antimicrobial Stewardship in Urosepsis

Oh TH

Since the latest knowledge on the treatment and countermeasures for sepsis is being updated at a rapid pace, becoming familiar with the Surviving Sepsis guidelines is helpful for patient prognosis....
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Adhesion of biofilm, surface characteristics, and mechanical properties of antimicrobial denture base resin

Teixeira ABV, Valente MLdC, Sessa JPN, Gubitoso B, Schiavon MA, dos Reis AC

PURPOSE This study incorporated the nanomaterial, nanostructured silver vanadate decorated with silver nanoparticles (AgVO3), into heat-cured resin (HT) at concentrations of 2.5%, 5%, and 10% and compared the adhesion of multispecies...
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Approach to Patients with Consecutive Helicobacter pylori Eradication Failure

Kim SE

Helicobacter pylori (H. pylori) is associated with various gastrointestinal disorders, such as gastritis, peptic ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Therefore, the International Agency for Research on Cancer,...
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Changing Epidemiology of Pathogenic Bacteria Over the Past 20 Years in Korea

Bae MH, Kim MS, Kim TS, Kim S, Yong D, Ha GY, Ryoo NH, Uh Y, Shin JH, Lee HS, Sohn YH, Shin S, Kim MN

Background: The epidemiology of pathogenic bacteria varies according to the socioeconomic status and antimicrobial resistance status. However, longitudinal epidemiological studies to evaluate the changes in species distribution and antimicrobial susceptibility...
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Use of Antibiotics Within the Last 14 Days of Life in Korean Patients: A Nationwide Study

Wi YM, Kwon KT, Hwang S, Bae S, Kim Y, Chang HH, Kim SW, Cheong HS, Lee S, Jung DS, Sohn KM, Moon C, Heo ST, Kim B, Lee MS, Hur J, Kim J, Yoon YK, aASRCoKSfAT

Background: Antimicrobial prescriptions for serious chronic or acute illness nearing its end stages raise concerns about the potential for futile use, adverse events, increased multidrugresistant organisms, and significant patient and...
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Core Elements for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals

Cheong HS, Park KH, Kim HB, Kim SW, Kim B, Moon C, Lee MS, Yoon YK, Jeong SJ, Kim YC, Eun BW, Lee H, Shin JY, Kim Hs, Hwang IS, Park CS, Kwon KT, Korean Society for Antimicrobial Therapy, The Korean Society of Infectious Diseases, Korean Society for Healthcare-associated Infection Control and Prevention, Korean Society of Pediatric Infectious Diseases, Korean Society of Health-System Pharmacists

Currently, antimicrobial resistance (AMR) is a major threat to global public health. To overcome this crisis, antimicrobial stewardship programs (ASPs) have been proposed. An ASP supports the optimal use of...
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Isolation and Antimicrobial Susceptibility of Nontuberculous Mycobacteria in a Tertiary Hospital in Korea, 2016 to 2020

Kim KJ, Oh SH, Jeon D, Chang CL

Background: There is a global increase in isolation of nontuberculous mycobacteria (NTM). The aim of the study was to analyze longitudinal trends of NTM identification and pattern of antimicrobial susceptibility...
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Antimicrobial activity of candidate probiotic Streptococcus salivarius against Gram-positive bacteria in oral cavity

Lee SH, Baek DH

Objectives: The aim of this study is to investigate antimicrobial activity in isolated Streptococcus salivarius against Gram-positive bacteria related oral diseases. Methods: S. salivarius was used in G2, G7, K12,...
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Antimicrobial effects of green tea extract-containing dentifrice

You EJ, Cho JW, Yoo HJ, Yea JS

Objectives: This study aimed to evaluate the antibacterial activity of green tea extract containing dentifrice on oral disease-causing bacteria. Methods: The antibacterial activity of green tea extract containing dentifrice was examined...
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Clinical Usefulness of the QMAC-dRAST System for AmpC β-lactamase-Producing Enterobacterales

Choi H, Kim D, Kwon M, Byun JH, Jin B, Hong KH, Lee H, Yong D

Background: Rapid antimicrobial susceptibility testing (RAST) is important for the appropriate treatment of bloodstream infections. The QMAC-dRAST system (QuantaMatrix Inc., Korea) can directly perform RAST using positive blood culture samples...
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Predicting Phenotypic Antimicrobial Resistance in Escherichia coli Isolates, Using Whole Genome Sequencing Data

Kim H, Kim YA, Seo YH, Lee H, Lee K

Background: The application of genotypic antimicrobial sensitivity tests (ASTs) is dependent on the reliability of the predictions of phenotypic resistance. In this study, routine AST results and the presence of...
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Assessment of the Synergistic Effect of Seven Antimicrobial Combinations on Extensively DrugResistant Acinetobacter baumannii Strains

Kim CM, Ko YJ, Choi JA, Kang SH, Park G, Jang SJ

Background: To solve the difficulty in determining the appropriate treatment regimen for patients infected with extensively drug-resistant Acinetobacter baumannii (XDRAB), it is necessary to develop various strategies to increase the...
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Antimicrobial Resistance Patterns of Acinetobacter baumannii and Pseudomonas aeruginosa Isolated From Vulnerable Patients in Korea, 2021

Kim YA, Jeong SH, Shin JH, Shin KS, Shin JH, Kim YR, Kim HS, Uh Y, Ryoo NH

Background: We compared the antimicrobial resistance rates (AMRs) of major glucose nonfermenting gram-negative bacilli, Acinetobacter baumannii and Pseudomonas aeruginosa, under different clinical conditions. The purpose of the study was to...
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Current Status and Prospects of the National Antimicrobial Resistance Surveillance System, Kor-GLASS

Kim D, Choi MH, Hong JS, Shin JH, Jeong SH

Antimicrobial-resistant bacteria have been increasingly reported worldwide, and surveillance plays an important role in preventing the further dissemination of these organisms. The World Health Organization suggested the Global Antimicrobial Resistance...
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Core Elements for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals

Cheong HS, Park KH, Kim HB, Kim SW, Kim B, Moon C, Lee MS, Yoon YK, Jeong SJ, Kim YC, Eun BW, Lee H, Shin JY, Kim Hs, Hwang IS, Park CS, Kwon KT, KSfATTKSoIDKSfHaICaPKSoPIDTKSo

Currently, antimicrobial resistance (AMR) is a major threat to global public health. The antimicrobial stewardship program (ASP) has been proposed as an important approach to overcome this crisis. ASP supports...
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Implementation of Procalcitonin in Antibiotic Stewardship: Derivation of a Consensus Algorithm for Procalcitonin Use in Clinical Practice

Park DW, Choi JY, Kim CJ, Kim JH, Kim HB, Lee DG

Reducing antibiotics overuse is essential to minimize antibiotics related side effects and to prevent the emergence of multidrug-resistant bacteria. Procalcitonin (PCT) guided antibiotics therapy has been reported to be safe...
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Current Status and Prospect of Qualitative Assessment of Antibiotics Prescriptions

Park SY, Kim YC, Lee R, Kim B, Moon SM, Kim HB, KSGfAS

Identifying inappropriately prescribed antibiotics for infectious diseases by monitoring the quality of antibiotics use is essential for effective implementation of antibiotic stewardship. Qualitative assessment of the use of antibiotics has...
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Clinical Utility of Procalcitonin on Antibiotic Stewardship: A Narrative Review

Kim JH

Procalcitonin (PCT) was discovered as a useful marker for bacterial infection. Following its discovery, there have been a substantial number of clinical studies conducted to evaluate the presence of bacterial...
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Expression of Antimicrobial Peptides in Psoriasiform Mouse Models

Kim SE, Lee SE, Kim SC, Kim JH

  • KMID: 2536318
  • Korean J Dermatol.
  • 2022 Nov;60(9):585-592.
Background: Psoriasis is a chronic inflammatory skin disease. Despite the current focus on T cells in the pathogenesis of psoriasis, keratinocytes within the psoriatic epidermis are also abnormal in many...
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Beta-Lactam Plus Macrolide for Patients Hospitalized With CommunityAcquired Pneumonia: Difference Between Autumn and Spring

Kim Y, Jeon Y, Kwon KT, Bae S, Hwang S, Chang HH, Kim SW, Lee WK, Yang KH, Shin JH, Shim EK

Background: The 2017 Korean guideline on community-acquired pneumonia (CAP) recommended beta-lactam plus macrolide combination therapy for patients hospitalized with severe pneumonia, and beta-lactam monotherapy for mild-to-moderate pneumonia. However, antibiotic treatment regimen...
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