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The Protective Effect of Green Tea Extract on Alpha-amanitin Induced Hepatotoxicity

An SH, Sun KH, Hong R, Lee BR, Park Y

PURPOSE: Alpha-amanitin induces potent oxidative stress and apoptosis, and may play a significant role in the pathogenesis of hepatotoxicity. This study examined the mechanisms of α-amanitin-induced apoptosis in vitro, and...
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Antidotes Stocking and Delivery for Acute Poisoning Patients at 20 Emergency Departments in Korea 2015–2017

Lee S, Youn HD, Chang H, Won S, Kim KH, Oh BJ

PURPOSE: The National Emergency Medical Center has been running a project for the storage and delivery of antidotes for acute poisoning patients of the Department of Health and Welfare, Korea....
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The Effect of Glehnia Littoralis on Alpha-amanitin Induced Hepatotoxicity in a Murine Model

Ryu CY, Sun KH, Hong R, Park Y

PURPOSE: Glehnia littoralis has been reported to have several pharmacological properties but no in vivo reports describing the protective effects of this plant on α-amanitin-induced hepatotoxicity have been published. α-Amanitin...
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Extracorporeal Life Support in Acute Poisoning

Lee SJ, Han GS, Lee EJ, Kim DH, Park KY, Lee JY, Kim SJ, Lee SW

PURPOSE: Cardiovascular or respiratory complications of acute intoxication are the most common causes of mortality. Advanced cardiac life support (ACLS) or specific antidotes help manage these cardiac or respiratory complications...
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Consensus Guides on Stroke Thrombolysis for Anticoagulated Patients from Japan: Application to Other Populations

Toyoda K, Yamagami H, Koga M

Development of direct oral anticoagulants and their antidotes has led to the need to reconsider the eligibility of acute stroke patients who have been taking oral anticoagulants for intravenous thrombolysis....
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Non-Vitamin K Oral Anticoagulants Associated Bleeding and Its Antidotes

Steiner T, Köhrmann , Schellinger PD, Tsivgoulis G

Oral anticoagulant-associated intracerebral hemorrhage (OAC-ICH) accounts for nearly 20% of all ICH. The number of patients with an indication for oral anticoagulant therapy (OAT) increases with increasing age. OAT became...
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Hemorrhagic pericarditis associated with rivaroxaban in an atrial fibrillation patient with pacemaker

Rhew SH, Kim SS

Rivaroxaban is a new oral anticoagulant used for the prevention of stroke in patients with atrial fibrillation. Hemorrhagic pericarditis is known to occur with rivaroxaban; however, only a few case...
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Pneumatosis Cystoides Intestinales and Portomesenteric Venous Gas following Anticholinesterase Pesticide Poisoning

Lee SH, Lee KW, Jung JH

Pneumatosis cystoides intestinalis and portomesenteric venous gas are uncommon radiological findings, but are found commonly in cases of bowel ischemia, or as a result of various non-ischemic conditions. A 72-year-old...
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Venous Thromboembolism Following Dantrolene Treatment for Neuroleptic Malignant Syndrome

Chen PH, Lane HY, Lin CH

Neuroleptic malignant syndrome (NMS) is one of the most severe iatrogenic emergencies in clinical service. The symptoms including sudden consciousness change, critical temperature elevation and electrolytes imbalance followed by mutli-organ...
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Acute Kidney Injury after Intravenous Injection of an Organophosphate Compound

Lee JY, Sung WY, Lee IY, Seo SW, Lee WS

Poisoning may result from self-injection. Previous reports have described acute cholinergic crisis, intermediate syndrome, and delayed toxicity resulting from parenteral organophosphate administration. These complications have been managed with antidotal and...
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A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy

Shin HJ, Lim H

  • KMID: 2328241
  • J Korean Soc Clin Toxicol.
  • 2016 Jun;14(1):60-65.
Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine....
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A Clinical Analysis of Patients Who Visited Emergency Department due to Chemical Incident Occurred at Industrial Place: A Retrospective Study

Shin HJ, Oh SK, Yoo BD, Jun DH, Lee DH, Woo KH, Yoon SY, Choi SY

  • KMID: 2133232
  • J Korean Soc Clin Toxicol.
  • 2015 Dec;13(2):78-86.
PURPOSE: The purpose of this study is to understand what kinds of chemical substances have been used annually and to investigate incidents that occurred due to chemical hazard release and...
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Kind and Estimated Stocking Amount of Antidotes for Initial Treatment for Acute Poisoning at Emergency Medical Centers in Korea

Sohn CH, Ryoo SM, Lim KS, Kim W, Lim H, Oh BJ

Antidotes for toxicological emergencies can be life-saving. However, there is no nationwide estimation of the antidotes stocking amount in Korea. This study tried to estimate the quantities of stocking antidotes...
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Lipid Emulsion in the Successful Resuscitation of Local Anesthetic Toxicity after Ankle Block

Park SH, Kwak SH, Yoo KY, Lee HJ, Yook KB, Kim SJ

Unexpected occurrence of local anesthetic toxicity is not rare and can cause fatal complications that do not respond to any known drug of intervention. Recently, the successful use of lipid...
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Antidote for acquired methemoglobinemia: methylene blue

Lee KW, Lee JB

Methylene blue (MB) is an effective antidote for methemoglobinemia. MB is a basic dye, yielding a blue solution. In the human body, hemoglobin is the oxygen-carrying protein including a ferrous...
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Antidotes of cyanide intoxication

Lee SW, Kim JS

Cyanide poisoning can occur from industrial disasters, smoke inhalation from fire, food, and multiple other sources. Cyanide inhibits mitochondrial oxidative phosphorylation by blocking mitochondrial cytochrome oxidase, which in turn results...
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Antidote for acetaminophen poisoning: N-acetylcysteine

Chun BJ, Moon JM, Kim SH

N-acetylcysteine (NAC) is widely recognized as the antidote of choice for acetaminophen overdose. Acetaminophen is a commonly used analgesic and antipyretic agent, and its use is one of the most...
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Need for stocking of emergency antidotes

Roh HK

No abstract available.
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The Experiences of the Emergency Antidote Stock and Delivery Service by the Korean Poison Information Center

Park SY, Oh BJ, Sohn CH, Jeong RB, Lim KS, Kim W, Ryoo SM, The research society for emergency antidotes stock and delivery system in Korea

  • KMID: 1482712
  • J Korean Soc Clin Toxicol.
  • 2013 Jun;11(1):9-18.
PURPOSE: Antidotes for toxicological emergencies can be life-saving. However, there is no nationwide stocking and delivery system for emergency antidotes in Korea. We report on a two-year experience of a...
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Successful treatment by exchange transfusion of a young infant with sodium nitroprusside poisoning

Baek JG, Jeong HL, Park JS, Seo JH, Park ES, Lim JY, Park CH, Woo HO, Youn HS, Yeom JS

Although sodium nitroprusside (SNP) is often used in pediatric intensive care units, cyanide toxicity can occur after SNP treatment. To treat SNP-induced cyanide poisoning, antidotes such as amyl nitrite, sodium...
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