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Metagonimus yokogawai: a 100-kDa Somatic Antigen Commonly Reacting with Other Trematodes

Han ET, Yang HJ, Park YJ, Park JH, Chai JY

  • KMID: 1792170
  • Korean J Parasitol.
  • 2014 Apr;52(2):201-204.
This study was undertaken to characterize the properties of a 100 kDa somatic antigen from Metagonimus yokogawai. Monoclonal antibodies (mAbs) were produced against this 100 kDa antigen, and their immunoreactivity...
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Detection of Gnathostoma spinigerum Antibodies in Sera of Non-Traumatic Subarachnoid Hemorrhage Patients in Thailand

Kitkhuandee A, Munkong W, Sawanyawisuth K, Janwan P, Maleewong , Intapan PM

Gnathostoma spinigerum can cause subarachnoid hemorrhage (SAH). The detection of specific antibodies in serum against G. spinigerum antigen is helpful for diagnosis of neurognathostomiasis. There is limited data on the...
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Dot-Blot Immunoassay of Fasciola gigantica Infection using 27 kDa and Adult Worm Regurge Antigens in Egyptian Patients

Kamel HH, Saad GA, Sarhan RM

The purpose of the present study was to evaluate the potential role of the 27-Kilodalton (KDa) antigen versus Fasciola gigantica adult worm regurge antigens in a DOT-Blot assay and to...
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Monoclonal Antibody-Based Dipstick Assay: A Reliable Field Applicable Technique for Diagnosis of Schistosoma mansoni Infection Using Human Serum and Urine Samples

Demerdash , Mohamed S, Hendawy M, Rabia I, Attia M, Shaker Z, Diab TM

A field applicable diagnostic technique, the dipstick assay, was evaluated for its sensitivity and specificity in diagnosing human Schistosoma mansoni infection. A monoclonal antibody (mAb) against S. mansoni adult worm...
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Evaluation of IgG4 Subclass Antibody Detection by Peptide-Based ELISA for the Diagnosis of Human Paragonimiasis Heterotrema

Intapan PM, Sanpool O, Janwan P, Laummaunwai P, Morakote N, Kong Y, Maleewong

A synthetic peptide was prepared based on the antigenic region of Paragonimus westermani pre-procathepsin L, and its applicability for immunodiagnosis for human paragonimiasis (due to Paragonimus heterotremus) was tested using...
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A Clonorchis sinensis-specific antigen that detects active human clonorchiasis

Kim SI

A Clonorchis sinensis-specific antigen in excretory-secretory product of C. sinensis (CsE) was assessed in human clonorchiasis by immunoblot. Thirty and 7 kDa antigens of CsE2, one of four different batches...
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Immunoblot patterns of clonorchiasis

Hong ST, Kho WG, Lee M, Lee JS, Lee SH

Clonorchis sinensis is a liver fluke which is the most prevalent helminth of humans in Korea. The better diagnostic measure of clonorchiasis is required for its nationwide control program. The...
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Seroprevalence of Trichinella sp. in Wild Boars (Sus scrofa) from Yanggu-gun, Gangwon-do, Korea

Lee HJ, Chung OS, Kim JL, Lee SH, Yoo YB, Seo M

A total 7 outbreaks of trichinellosis have occurred in Korea, mostly as a result of consumption of raw wild boar (Sus scrofa) meat. Since only 1 serological survey on wild...
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Cutaneous Gnathostomiasis with Recurrent Migratory Nodule and Persistent Eosinophilia: a Case Report from China

Cui J, Wang Y, Wang ZQ

The present study reports a human case of cutaneous gnathostomiasis with recurrent migratory nodule and persistent eosinophilia in China. A 52-year-old woman from Henan Province, central China, presented with recurrent...
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Cross-reactivity of Toxocariasis with Crude Antigen of Toxascaris leonina Larvae by ELISA

Jin Y, Shen C, Huh S, Choi MH, Hong ST

Roundworms of Toxocara canis and Toxascaris leonina are common gastrointestinal helminths of canids over the world. Humans are infected with T. canis larvae through ingestion of infective eggs in contaminated...
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Antigenic profile and localization of Clonorchis sinensis proteins in the course of infection

Hong SJ, Kim TY, Song KY, Sohn WM, Kang SY

In the course of Clonorchis sinensis infection, antigens presented to the hosts may be in a close relation to growth of the fluke. The antigenic proteins stimulating IgG antibody production...
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Activities of different cysteine proteases of Paragonimus westermani in cleaving human IgG

Chung YB, Yang HJ, Kang SY, Kong Y, Cho SY

Cleaving host immunoglobulins is a well known mechanism of evading host immune reactions exploited by helminth parasites. Secreted cysteine proteases of helminth are a part of enzymes cleaving host IgG....
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Variation of antigenic proteins of eggs and developmental stages of Paragonimus westermani

Kong Y, Chung JY, Yun DH, Kim LS, Kang SY, Ito A, Ma L, Cho SY

Diagnosis of early paragonimiasis is difficult because parasitological evidence is not easily obtained. Antibody tests have been proposed as a good substitute for classical diagnostic techniques. Using the...
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Intestinal Paragonimiasis with Colonic Ulcer and Hematochezia in An Elderly Taiwanese Woman

Liu CT, Chen YC, Chen TH, Barghouth , Fan CK

  • KMID: 1792129
  • Korean J Parasitol.
  • 2012 Dec;50(4):349-352.
A 94-year-old female with end-stage renal disease presents with fever, fatigue, and hematochezia. She had previously resided in Hunan Province, China, and Myanmar, and she immigrated to Taiwan 30 years...
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Modulation of Antibody Responses against Gnathostoma spinigerum in Mice Immunized with Crude Antigen Formulated in CpG Oligonucleotide and Montanide ISA720

Intapan PM, Hirunpetcharat C, Kularbkaew C, Yutanawiboonchai W, Janwan P, Maleewong

This study aimed to investigate the antibody responses in mice immunized with Gnathostoma spinigerum crude antigen (GsAg) incorporated with the combined adjuvant, a synthetic oligonucleotide containing unmethylated CpG motif (CpG...
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Effects of anti-IgE mAb on serum IgE, Fc epsilon RII/CD23 expression on splenic B cells and worm burden in mice infected with Paragonimus westermani

Shin MH, Min HK

It is generally accepted that parasite-specific IgE plays a crucial role in host defense against helminthic parasites. However, the role of high levels of nonspecific IgE in helminthic infections is...
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Seroepidemiological observation of Taenia solium cysticercosis in epileptic patients in Korea

Kong Y, Cho SY, Cho MS, Kwon OS, Kang WS

Prevalence survey of neurocysticercosis was made in a mixed epilepsy patients of Changmi Club in Korea. From February 1987 to July 1990, a total of 2,667 randomly selected patients at...
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Tissue parasitic helminthiases are prevalent at Cheongjin, North Korea

Shen C, Li S, Zheng S, Choi MH, Bae YM, Hong ST

We investigated a small-scale serological survey to screen tissue-parasitic helminthiases of North Koreans as one of research programs for re-unification of Korea. Soil-transmitted helminthiases were found highly prevalent among North...
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Recurred Sparganosis 1 Year after Surgical Removal of a Sparganum in a Korean Woman

Lee YI, Seo M, Park HW

Sparganosis, an infection due to the plerocercoid of Spirometra erinacei, are found worldwide but the majority of cases occur in East Asia including Korea. This report is on a recurred...
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An Outbreak of Trichinellosis by Consumption of Raw Soft-Shelled Turtle Meat in Korea

Jeong JT, Seo M, Hong ST, Kim YK

Trichinellosis transmission to humans via the consumption of reptile meat is rare worldwide. In Korea, however, 2 such outbreaks, possibly via consumption of soft-shelled turtle meat, have occurred in 2...
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