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Bone mineral density change during adjuvant chemotherapy in pediatric osteosarcoma

Ahn JH, Cho WH, Lee JA, Kim DH, Seo JH, Lim JS

PURPOSE: Osteoporosis is currently receiving particular attention as a sequela in survivors of childhood osteosarcoma. The aim of this study was to evaluate bone mineral density (BMD) changes during methotrexate-based...
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Screening newborns for metabolic disorders based on targeted metabolomics using tandem mass spectrometry

Yoon HR

The main purpose of newborn screening is to diagnose genetic, metabolic, and other inherited disorders, at their earliest to start treatment before the clinical manifestations become evident. Understanding and tracing...
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Body mass index and body composition scaling to height in children and adolescent

Chung S

Childhood obesity prevalence has been increased and known to be related to various diseases and mortality in adult and body mass index (BMI) has been widely used as a screening...
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XYY syndrome: a 13-year-old boy with tall stature

Jo WH, Jung MK, Kim KE, Chae HW, Kim DH, Kwon AR, Kim HS

When evaluating the underlying causes of tall stature, it is important to differentiate pathologic tall stature from familial tall stature. Various pathologic conditions leading to adult tall stature include excess...
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Hypotonic hyponatremia by primary polydipsia caused brain death in a 10-year-old boy

Ko AR, Kim SJ, Jung MK, Kim KE, Chae HW, Kim DH, Kim HS, Kwon AR

Hypotonic hyponatremia by primary polydipsia can cause severe neurologic complications due to cerebral edema. A 10-year-and-4-month-old boy with a psychiatric history of intellectual disability and behavioral disorders who presented with...
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Qualitative assessment of precocious puberty-related user-created contents on YouTube

Nam HK, Bang SM, Rhie YJ, Park SH, Lee KH

PURPOSE: User-created content (UCC) has provided a considerable amount of medical information and become an important source. We aimed to evaluate the quality and scientific accuracy of precocious puberty-related UCC...
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Metabolic effects of polycystic ovary syndrome in adolescents

Han Y, Kim HS, Lee HJ, Oh JY, Sung YA

PURPOSE: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenic anovulation in women of reproductive age. We investigated the metabolic effects of lean and overweight adolescents with PCOS. METHODS: Anthropometric measurements and...
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A Leri-Weill dyschondrosteosis patient confirmed by mutation analysis of SHOX gene

Choi WB, Seo SH, Yoo WH, Kim SY, Kwak MJ

Leri-Weill dyschondrosteosis is characterized by SHOX deficiency, Madelung deformity, and mesomelic short stature. In addition, SHOX deficiency is associated with idiopathic short stature, Turner syndrome, and Langer mesomelic dysplasia. We...
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Clinical manifestations of testicular adrenal rest tumor in males with congenital adrenal hyperplasia

Yu MK, Jung MK, Kim KE, Kwon AR, Chae HW, Kim DH, Kim HS

PURPOSE: In male patients with congenital adrenal hyperplasia (CAH), the presence of testicular adrenal rest tumors (TARTs) have been reported, however their prevalence and clinical manifestations are not well known....
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The effect of early menarche on the sexual behaviors of Korean female adolescents

Cheong JI, Lee CH, Park JH, Ye BJ, Kwon KA, Lee YS, Yoo JH

PURPOSE: This study examined the relationships between early menarche and sexual behaviors among Korean female adolescents. METHODS: We analyzed data from the eighth Korea Youth Risk Behavior Web-based survey that was...
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